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痛觉过敏

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METHODS: Hyperalgesia was evaluated with the thermal paw withdrawallatency test before, and 3 and 7 days after CCI.

分别在 CCI 之前以及之后的3天和7天用热刺激缩爪潜伏期试验来评价痛觉过敏

Hyperalgesia after thermal stimulation is also mediated by non-NMDA, but not NMDA, receptors.

热刺激后痛觉过敏也由非 NMDA 受体而不是 NMDA 受体介导。

The IM injection of capsaicin resulted in a reliable report of pain, hyperalgesia, and referred pain.

肌注辣椒素可产生可靠的疼痛主诉、痛觉过敏和牵涉痛。

The occurrence of mechanical hypersensitivity of pain may be related with the method and degree of nerves damage.

出现机械性痛觉过敏,这可能与损伤神经的方式和多少有关。

The latter group showed marked pain, in particular, severe mechanical hyperalgesia, and predominantly small myelinated and unmyelinated fiber loss.

后一组突出表现为疼痛,特别是严重的机械性痛觉过敏,主要是小的有髓纤维和无髓纤维缺失。

Autogenous nucleus pulposus was removed from the coccygeal vertebral and placed into the back of left L(5~6) nerve root,The modle of the no...

结论杜仲腰痛丸有减轻非机械压迫性髓核对神经根损伤后所导致的机械痛觉过敏,提高痛阈的作用。

Objectives A rat model sciatic nerve crush injury was reproduced in rat, and behavioral changes, pain threshold, thermal withdrawal latency and the changes in c-fos expression in cornu dorsale medullae spinalis were examined, and the relationship between peripheral nerve regeneration and hyperpathia was explored.

目的 建立大鼠坐骨神经挤压模型,观察其神经恢复过程中行为学、机械痛阈值、热缩足反射潜伏期以及脊髓背角c-fos表达(对c-fos表达产物:Fos蛋白阳性的神经元进行计数)的改变,探讨外周神经损伤再生与痛觉过敏的关系。

The time course of expression of TNFα mRNA in the spinal cord is not completely consistent with the hyperalgesic behaviors, TNFα maybe more involved in the early phase of neuropathic pain.

脊髓TNFαmRNA的表达变化与大鼠痛觉过敏行为并不完全吻合,TNFα更多地参与神经病理性疼痛起始环节。

Subhypnotic concentrations of propofol did not lead to any hyperalgesic effects.

同时输注瑞辬太尼有协同止痛效果(0.025mg/kg/min和0.05mg/kg/min的瑞辬太尼分别比實otilde;照组减轻疼痛62%+/- 26%和58%+/- 25%),但是撤药后,疼痛和痛觉过敏要比實otilde;照组增徠。

"Sleep disruptions were similar in the NR and RD conditions, but did not involve REM sleep; the effects on pain threshold observed in the RD condition were therefore due specifically to the loss of REM sleep, not to the disruption of sleep per se," noted Dr. Roehrs."We found that REM loss itself was hyperalgesic."

Roehrs博士强调,在无快速眼动睡眠的因素下,NR及RD的睡眠干扰情况皆类似;在RD状态时,疼痛感受值会受到影响,这主要是因为丧失快速眼动睡眠的关系,而不是睡眠本身受到影响;我们发现,快速眼动睡眠的丧失,本质上就是痛觉过敏

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