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In this thesis, some of these questions have been studied in detail by expressing the antigenes of RSV、hepatitis A virus and hepatitis B virus in the vaccinia vector.

本论文通过对RSV、HAV和HBV等多种抗原在痘苗病毒载体中表达,对基因工程活疫苗面临的一些基本问题进行了详细研究。

In order to reinforce the immune effect, the ME6 gene and ME7-1 gene were co-expressed in the same vaccinia virus.

为加强免疫效果本文还将ME6和ME7-1基因在同一个痘苗病毒中进行了共表达。

Keywords variola virus;vaccinia virus;drug screening;model of cell;model of animal

天花病毒;痘苗病毒;药物筛选;细胞模型;动物模型

It was the first time to evaluate the measles recombinant vaccinia vaccine strain in clinical trials.

RVJML11HA75FKIL2作为麻疹重组痘苗病毒活疫苗,首次在5-6岁的儿童中进行免疫加强效果以及在7-10月龄的婴幼儿中进行初次免疫效果的观察。

Cell biologist Michael Way of the London Research Institute agrees that other viruses may also use the vaccinia infection strategy.

伦敦研究所的细胞生物学家迈克尔·韦同样认为,其他的病毒也可能运用了痘苗的感染策略。

Objective: Safety and possibility of Recombination Human CEA Vaccinia Virus were detected in rabbits to proveide experimental data for gene therapy in cancer.

目的:检测重组人CEA痘苗病毒(HumanCEARecombinationVacciniaVirus,rV-CEA)在动物体内应用的安全性与可行性,为肿瘤的基因治疗提供实验依据。

The virulence and immunogenicity of vaccinia virus vector are the two aspects about which the researchers care in the study of genetically engineered live vaccine.

痘苗病毒载体的毒力和免疫原性是研究人员在基因工程活疫苗研究中所关心的两个方面。

For the next 3 weeks, the child was treated with a combination of immunotherapy and antivirals targeting vaccinia virus, but on March 10, the illness had progressed to hypothermia and hemodynamic instability requiring vasopressor support.

接下来的三周患儿接受免疫疗法和靶向痘苗病毒的抗病毒的联合治疗,但3月10日病情进一步加重,出现体温过低和血液动力学不稳定需要使用血管加压药。

Despite all of this study, researchers have missed a curious feature of the virus's biology, says virologist Geoffrey Smith of Imperial College London.

伦敦帝国理工学院的病毒学家杰弗里·史密斯说,尽管对痘苗病毒进行了很多研究,研究人员却忽视了这种病毒生态中一个奇怪的特征。

Objective: To evaluate the protective ability of vaccinia virus vectored multi-epito pe live vaccine candidate for plasmodium falciparumin experimental anim als, and to lay foundation for next testing on Aotus sp.

摘 要 目的:探讨恶性疟原虫保护性抗原复合基因-痘苗病毒重组活疫苗候选株在实验动物的抗疟原虫攻击能力,为下一步进入夜猴及人体试验奠定基础。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。