痘病毒

Because these viruses abortively infect human and most mamralian cells yet still effecfivelypresent encoded forgein genes to the host inmune system Compared with the replication-compentent vaccinin virus,the MVA modified vaccinia Ankara ,all a highly attenuated vaccinia virus,lost hte ability to replicate in human and most mamralian cells except BHK-21 and CEF cells.

痘苗病毒做为一种载体在外源抗原蛋白的递呈方面有着很大的潜力。因为这类病毒不能感染人和大多数哺乳动物细胞，却可以有效地将外源基因编码的蛋白递呈给宿主免疫系统。

These two types construct the basis of codon usage on the function and expression stage, respectively.

痘苗病毒以基因的功能构筑密码子使用类型的基础，而腺病毒则以表达的时相构筑密码子使用类型的基础。

Challenge was made after one month of immunization by vein. Re sults:The parasitemia of recombinant virus immunized monkey was 0.0 1%in first tw o days of post-challenge. No parasites were determined from third to 12th day. W hereas the parasitemia of control virus immunized-monkey and blank control monk ey rose progressively,went to 2.5%～6.0% at 6th～8th days of post-challenge, an d the t ime of parasitemia was 12～13 days.

结果： 在免疫后1个月攻虫，重组痘苗病毒免疫猴从第3天一直到第12 d的采血检查中均未发现疟原虫；非重组痘苗病毒免疫猴第3天后原虫感染率上升，第6天原虫感染率最高达到6.0%，而后原虫感染率逐渐下降，原虫持续时间为13天；空白对照猴第3天后原虫感染率也上升，第8天原虫感染率最高达到2.5%，而后原虫感染率逐渐下降，原虫持续出现时间为12 d。

They discovered that vaccinia produces two proteins right after it infects a cell.

他们发现，痘苗感染一个细胞之后立即产生两种蛋白质，两种蛋白质结合在一起在细胞表面形成一种复合物，这种复合物能够阻止其他的痘苗病毒微粒进入细胞（病毒再次侵入细胞的过程叫做"重叠感染"）。

We adopted the codon usage of vaccinia virus to modified the codon usage of nef and expression them in two prokaryotic expression vector.

我们采用痘苗病毒总体密码子使用频率改造HIV的nef基因后，提高基因的AT含量，其对痘苗总体的CAI指数提高到0.9以上。

Despite all of this study, researchers have missed a curious feature of the virus's biology, says virologist Geoffrey Smith of Imperial College London.

伦敦帝国理工学院的病毒学家杰弗里·史密斯说，尽管对痘苗病毒进行了很多研究，研究人员却忽视了这种病毒生态中一个奇怪的特征。

When large quantities of viruses are required for vaccine production or chemical studies, the allantoic sac is utilized.

如绒毛尿囊膜是常用的接种部位，用于1、病毒滴定2、病毒形态学研究3、病毒鉴定，几种病毒能在绒毛尿囊膜上产生水泡样损伤，称为痘痕。

Efficiency: Bactericidal, Virucidal (incl. HBV,HCV,HIV,SARS,H5N1,Vaccinia,virua), and fungicidal100g 中含 Isopropanol 62.80g;Aqua bidest37.20g, Perfume and colorant free

生效范围：细菌，病毒（包括乙肝病毒，丙型肝炎病毒，爱滋病毒，SARS病毒，禽流感病毒，痘苗病毒）和真菌

After selecting a highly potent strain of poxvirus that was able to traffic to tumors when administered intravenously to mice the authors engineered the virus such that it would target only specific cancer cells -- those with increased expression of a protein known as E2F and/or activation of signaling downstream of a protein known as EGFR.

以毒攻毒：设计病毒，攻击肿瘤一种新的治疗癌症的方法正在开发中：用病毒感染肿瘤杀死癌细胞留下正常细胞不被伤害。这些病毒以病毒疗法而著称。在一项新的研究当中，David Kirn 和他在旧金山Jennerex生物疗法同事已经描述出利用新病毒疗法后老鼠和兔子抗肿瘤效应的发展。在选择高度特异性痘状病毒后才能有效的到达肿瘤生长地方，然后通过静脉途径给老鼠。

The fluorescent antibody was prepared with IgG purified from rabbit anti-goatpox virus serum and used to detect the antigen of GPV in pock samples and BHK-21 cells infected respectively with GPV strains B,Y,LD and QL.

用兔抗山羊痘病毒IgG制备荧光抗体，检测了临床发病山羊皮肤痘疹切片和山羊痘病毒B、Y、LD和QL株感染的BHK-21细胞中的病毒抗原。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。