痉挛毒素

Objective:To investigate the cause and therapeutic methods for blepharospasm.

为探讨单侧眼轮匝肌痉挛的病因及治疗方法，对182例患者观察了临床症状、体征，进行了A型肉毒杆菌毒素治疗；36例作了肌电图检查，15例作了脑干磁共振血管成像检查。

Currently Botox has approval to treat medical disorders such as blepharospasm, cervical dystonia and cerebral palsy.

肉毒素目前已经批准治疗医疗紊乱，如眼睑痉挛、颈肌张力障碍、斜视和大脑中风和偏头痛。

Botulinum toxins were first researched in the late 1960s to treat neurological disorders and for that otox were first approved by the FDA in 1989 to treat eye muscle disorders like blepharospasm, uncontrollable blinking, and strabismus, crossed eyes.

肉毒毒素的研究，首次在六十年代后期治疗神经系统疾病，并为此otox首次核准由美国食品暨药物管理局在1989年治疗眼部肌肉疾病如眼睑痉挛，无法眨眼，斜视，眼划线。

Botulinum toxins were first researched in the late 1960s to treat neurological disorders and for that otox were first approved by the FDA in 1989 to treat eye muscle disorders like blepharospasm, uncontrollable blinking, and strabismus, crossed eyes and even for wrinkles.

肉毒毒素的研究，首次在六十年代后期治疗神经系统疾病，并为此otox首次核准由美国食品暨药物管理局在1989年治疗眼部肌肉疾病如眼睑痉挛，无法眨眼，斜视，越过眼睛，甚至皱纹。

Objective To explore the cause of hemifacial spasm and evaluate the therapeutic efficacy of botulin A.

目的 探讨面肌痉挛的病因，评估A型肉毒毒素治疗面肌痉挛的疗效。

Objective To observe clinical feature of patients with hemifacial spasm and therapeutic effect of Chinese botulinum toxin type A.

目的观察半侧面肌痉挛患者的临床表现和肉毒毒素对半侧面肌痉挛的治疗效果。

AIM: To explore the effects of botulinum toxin A in improving the abduction activity of carpometacarpal joint of thumb and spasm in spastic cerebral palsy patients with adduction deformity thumb.

目的：探讨A型肉毒毒素对痉挛型脑性瘫痪拇指内收畸形患者拇指腕掌外展活动度及痉挛的改善作用。

Methods 32 cases of patients with myospasm after head injury were inpatiens of neurosurgery and convalescent ward from february 2004 to january 2007, each of them was intramuscular injected botulinum toxin type adeeply and symmetrically.

选取32例2004年1月至2007年2月在我院神经外科及康复科治疗的脑外伤后肢体肌肉痉挛病人，每例行国产a型肉毒毒素痉挛肌等距离多点均匀深部注射治疗，每次注射总量不超过100u，每次注射1－2块肌肉。

intramuscular injection of Botulinum Toxin Type A deeply and symmetrically to treat myospasm after head injury is safe, simple, valid, has less complication, and worthy recommendation.

等距离深部肌注A型肉毒毒素治疗脑外伤后四肢肌痉挛安全有效，操作简单，并发症少，为康复治疗赢得时间，值得在临床推广。 A型肉毒毒素；肌痉挛；脑外伤；肌张力障碍；改良Ashworth量表；偏瘫

Abstract］ objective to observe the clinical value of botulinus toxin a on the treatment of spastic cerebral palsy for children.methods thirty children were injected with bta for spasticity treatment,the dosage was 2～5 u/kg; the therapeutic efficacy was evaluated by physician rating scale and dystonia was evaluated by improved ashworth and the result was done with statistical analysis.results 29 cases was obviously improved in symptoms after injection.no obvious side effects were found during and after injection.conclusion btx-a proves to be a simple,safe and effective method in the treatment of the spastic cerebral palsy.in short,it is a useful therapeutic option.

目的 探讨a型肉毒毒素对痉挛性小儿脑瘫的临床疗效。方法根据纳入标准，选择30例患儿作为观察对象，采用bta肌肉注射，剂量为2～5 u/kg。疗效评定：肌张力采用改良的ashworth法评价、prs评分，并进行统计学处理。结果 29例治疗后较治疗前症状明显改善，其prs指标治疗前后比较差异显著（p.01）；按ashworth分级，30例中，治疗前最高5级，最低2级，平均4级。注射后除一例无效外，肌张力降为最高4级，最低1级，平均2级。治疗中及治疗后无明显副作用发生。结论 bta治疗痉挛性小儿脑瘫，副作用小，方法简单，刺激性小，维持有效时间长。bta是改善小儿脑瘫肌痉挛和肢体功能的一种实用性的治疗选择。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新