痉挛毒

Results Women were more often affected than men(1.83:1) and 53 patients were older than 40 years. The involved parts were as follows: eyelid 58 cases (89.2%), mouth and mandibula 46 cases(70.8%),neck 17 cases(26.2%). The symptom at onset were blepharospasm 42 cases(64.6%) or oromandibular dystonia 17 cases(26.2%).In part of the patients, cranial MRI examination could find focus in brainstem or basal ganglia. Among 37 patients treated with oral drugs, 4 cases were almost cured, 16 cases improved and 17 cases showed no effect. While in 15 patients treated through chiostridium botulinum toxin injection, 5 were almost cured, 9 improved and 1 had no effect.

结果 男女患病比率为1：1.83，40岁以上发病53例，受累部位依次为眼睑58例（89.2%）、口-下颌46例（70.8%）、颈部17例（26.2%）；首发症状以眼部不适、眼睑痉挛最多（42例，占64.6%），口-下颌肌张力障碍次之（17例，占26.2%）；14例行头MRI检查者8例发现脑干或基底节区病灶；口服药物治疗37例，显效4例，有效16例，无效17例；15例行肉毒毒素局部注射者显效5例，有效9例，无效1例。

The involved parts were as follows: eyelid 58 cases (89.2%), mouth and mandibula 46 cases(70.8%),neck 17 cases(26.2%). The symptom at onset were blepharospasm 42 cases(64.6%) or oromandibular dystonia 17 cases(26.2%).In part of the patients, cranial MRI examination could find focus in brainstem or basal ganglia. Among 37 patients treated with oral drugs, 4 cases were almost cured, 16 cases improved and 17 cases showed no effect. While in 15 patients treated through chiostridium botulinum toxin injection, 5 were almost cured, 9 improved and 1 had no effect.

结果 男女患病比率为1：1.83，40岁以上发病53例，受累部位依次为眼睑58例（89.2%）、口-下颌46例（70.8%）、颈部17例（26.2%）；首发症状以眼部不适、眼睑痉挛最多（42例，占64.6%），口-下颌肌张力障碍次之（17例，占26.2%）；14例行头MRI检查者8例发现脑干或基底节区病灶；口服药物治疗37例，显效4例，有效16例，无效17例；15例行肉毒毒素局部注射者显效5例，有效9例，无效1例。

objective to research the means and effect of intramuscular injection of botulinum toxin type a to treat myospasm after head injury.

目的 探讨a型肉毒毒素治疗脑外伤后四肢肌痉挛的注射方法及疗效。

intramuscular injection of botulinum toxin type a deeply and symmetrically to treat myospasm after head injury is safe, simple, valid, has less complication, and worthy recommendation.

等距离深部肌注a型肉毒毒素治疗脑外伤后四肢肌痉挛安全有效，操作简单，并发症少，为康复治疗赢得时间，值得在临床推广。

Methods Botulinum toxin type A was injected into neck muscles of 29 patients with idiopathic torticollis spasmodicus.

选取29例原发性痉挛性斜颈患者，应用A型肉毒毒素进行颈部肌肉注射治疗，检测和比较注射前、注射后1周和12～16周尺神经及胫神经F波的潜伏期及出现率。

Doctor: Tetanus is a toxemia .The toxin diffuses throughout the tissues and involves the neuromuscular end-organs, And so to cause spasm.

医生：破伤风是一种毒血症，毒素于组织间弥散，累及神经肌肉终末器官并引起肌肉痉挛。

DATA SYNTHESIS: From the synthesis materials we found that there was little progress on the drug treatment of muscular spasm of cerebral palsy in recent years. The main drugs for treatment still were valium, baclofen, tizanidine, anhydrous alcohol, phenol, A-type borulinus toxin etc. common used drugs.

资料综合：综合资料发现近几年脑性瘫痪肌痉挛的药物治疗进展不多，治疗的主要药物仍然是苯甲二氮草、巴氯芬、替扎尼定、无水乙醇、苯酚、A型肉毒毒素等常用药物，给药的途径主要有口服、鞘内注射或肌肉注射。

In recent years, very carefully-timed and measured doses of botulinum toxin have been usefully applied to a number of conditions, such as spasms, tennis elbow, recovery after stroke, teeth-grinding, etc.

在近年来，非常仔细地定时和计量剂量的肉毒杆菌毒素已是有益的适用于若干条件，如痉挛，网球肘，恢复中风后，牙齿磨等。

Abstract］ Objective To observe the clinical value of botulinus toxin A on the treatment of spastic cerebral palsy for children.

目的 探讨A型肉毒毒素对痉挛性小儿脑瘫的临床疗效。方法根据纳入标准，选择30例患儿作为观察对象，采用BTA肌肉注射，剂量为2～5 u/kg。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新