症状学的

Newborn Balb/c mice were infected intracranially with CVB3 (10〓). Indirect immunofluorescent staining approved the infection. We monitored daily for overt signs of infection and pathological changes (nervous cell necrosis, edema, etc). The most severe signs and pathologic changes happened at the third day postinfection.

本实验又选用日龄为2-3天的新生Balb/c小鼠，以10〓CVB3标准株颅内接种，逐日观察CVB3引致小鼠脑组织感染的病理改变及症状一周，并以间接免疫荧光法证实小鼠脑内感染确立，结果显示：10〓CVB3导致小鼠颅内感染成立；小鼠出现明显的症状体征；组织学呈现明显的神经细胞变性、坏死及细胞内、外严重水肿，且以第三天为最重。

Abstract］ objective to study the knowledge of the imaging manifestation of x-ray and ct in peripheral small lung cancer.methods to collect twenty cases with no symptom in early time diagnosed by clinic and to retrospectively analyze their imaging features.results x-ray appeared patch,small node.ct appeared patch,small node,light lobulation,peripheral vessel convergence,pleural indentation sign.most of the diameter was 1.5 to 2 cm,with no mediastinum and pulmonary hilar lymph nodes diversion.furthermore the clinical symptom was not obviously.conclusion to be familiar and handling the sign mentioned above is the key to boost the diagnosis of small peripheral lung cancer.

目的 探讨周围型小肺癌的x线、ct影像学表现。方法收集临床和病理证实的早期无症状肺癌20例，对其影像学进行回顾分析。结果本组早期肺癌x线为斑片状、小结节状。ct表现为斑片状、小结节状、轻度分叶状肿块，小毛刺、血管集束征、胸膜凹陷征，大多直径在1.5～2 cm。无纵隔淋巴及肺门转移，且临床症状不明显。结论熟悉并掌握上述征象是提高小肺癌早期诊断率的关键。

So people attach great importance to the damage by its toxicity. The main target organ of manganese is nervous system. At the early stage, its major symptoms are neurasthenic syndrome and autonomic nerve functional disorder, and then the apparent damage to extracorticospinal tract nerves, similar to that of a Parkinson's disease.

锰的主要毒作用器官是神经系统，早期以神经衰弱综合征和植物神经功能紊乱为主，继而可出现明显的锥体外系神经受损症状，与帕金森病(Parkinson's disease，PD)症状类似，流行病学研究认为锰是PD发病的环境危险因素之一。

Result: 1、Ethology result:50 rats were injecting convulsive dose kainic acid, showing prodrome such as gaze, wet dog shake in the 0-30 minutes; 1-5 degree epileptic attack in the 30-60minutes; 4-5 degree repteately spontaneous epileptic attack in 60-90 minutes; then status epilepticus,SE-epileptic attack endurance became longer and interval became shorter with bulk salivas and various kinds psychomotor symptoms.

结果：1、行为学结果：SD大鼠(n=50)在注射惊厥剂量(10mg/kg)KA后，0-30min内动物出现凝视，湿狗样抖动(wet dog shake，WDS)等前驱症状；30-60min内动物出现1-5级癫痫发作；60-90min内动物反复自发出现4-5级癫痫发作；其后动物癫痫发作持续时间延长，间隔变短伴有大量唾液分泌，出现各种精神运动症状，呈现SE，SE后10天，用阈下剂量(5mg/kg)KA检测动物对癫痫刺激的敏感性。

The study, published in the January 2005 issue of the American Journal of Roentgenology, assessed 31 patients who had greater than 60% carotid artery stenosis--18 had symptoms of carotid artery disease, including transient or permanent episodes of neurologic dysfunction, whereas 13 had no history of stroke-related symptoms.

这项研究结果发表在2005年1月《美国X线学期刊》，研究了31例颈动脉狭窄超过60％的患者：18例有颈动脉疾病的症状，包括暂时性或者永久性神经功能障碍；13例没有脑卒中相关症状的疾病史。

Firstly, 112 symptoms of asthenia syndrome which frequency greater than or equal to 10% were clustered and recognized. Secondly, every group cases of asthenia syndrome after first stage clustering were clustered and recognized again to get corresponding sthenia syndrome. Thirdly, we searched for the distribution laws between the clustering result and the data of demography to get the distribution laws of every group characteristic symptoms corresponding asthenia syndrome, of sthenia syndrome corresponding every group asthenia syndrome.

首先根据频率大于10%的112个虚证症状进行聚类识别，再对聚类结果中每组虚证病例进行兼夹实证聚类识别，并对聚类识别结果与性别、年龄等人口学特征之间分布规律进行探索，从而得出每类虚证对应的特征症状分布规律及程度，虚证证候对应的兼夹实证分布规律，以及各类主次证候间辨证关系及发展趋势，及其与性别、年龄等人口学特征的分布规律。

Malignant plasmodium was founded in their blood samples.The epidemiological study showed,they had never gone to the higher malaria-epidemic areas in our country,such as Yunnan,Hainan,Guangxi,etc.During living overseas,they were all bitten by mosquito.Three cases were first infected,and others were recrudescence sufferers.When they came to hospital,the temperature was higher than 38.5℃.Except for the clinic symptom such as chill,fever,sweat etc.,five cases emerged tumid spleen and anaemia symptom.

结果〕温州口岸2005年1～7月共发现8例疟疾患者，均为国内人员国外感染，其中男性7例，女性1例，血液涂片均查到恶性疟原虫；流行病学个案调查结果显示，8例患者在国外期间均有蚊虫叮咬史；3例为初发病例，5例为复发病例；8例患者就诊时体温均超过38℃，并出现畏寒、发热、大汗等典型的疟疾临床症状，5例患者出现脾肿大和贫血症状，患者均无并发症状出现。

Of the research group commited a crime under the direct control of psychiatric symptoms, the commonest psychiatric symptoms were in order delusion of persecution, auditory hallucination, delusion of reference and paralogia.conclusion criminological characteristics of schizophrenic murder cases are obviously different from those of health adults', their responsibility evaluations are related to psychopathological features and severity.

研究组89%在精神症状直接支配下作案，最常见的精神症状依次为被害妄想、幻听、关系妄想、逻辑障碍。结论精神分裂症患者凶杀案件的犯罪学特征明显不同与正常人，其责任能力的评定与其精神病理学特征及严重程度有关。

①Headache at different levels was the commonest symptom for benign and malignant lesions. The visual loss was another common symptom. It is important to realize the relationship between visual symptom and space-occupied lessions in sphenoidal sinus and sellar area;②Imaging study is very important for the diagnosis of the lesions in sphenoidal sinus and sellar area;③It is helpful to do needle-aspirating biopsy under endoscopy to confirm the pathologic diagnosis.

①良恶性病变均以头痛为第一常见症状，眼部症状为第二常见症状，掌握眼部症状与蝶鞍占位的关系对及早诊断意义重大；②影像学检查对此区域病变的发现和诊断起着重要作用；③内窥镜的应用及镜下穿刺活检亦对诊断十分有帮助。

After cessation of CsA, the clinical symptoms of SGVHD (such as weight loss, diarrhea, hunching, ranting) were observed. The histological changes of murine liver, colon, skin, thymus and ear were examined by routine pathological methods.

停药后每日观察小鼠临床症状，在小鼠出现GYHD样症状时，取肝脏、结肠、耳朵、皮肤和胸腺进行组织学检查，并检测肝脏、结肠组织细胞因子和协同刺激分子的表达。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

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