病理解剖的

Dr. Guo is certified in Anatomic Pathology and Cytopathology by the American Board of Pathology.

获得了由美国病理学会颁发的解剖病理学和细胞病理学资质认证。

Methods: Rat models of chronic renal failure were made by cut 5/6 kindney or fed with feedingstuff which contains adenine(0.75%) for 4 weeks. Experimental treatment was applied by giving Yi Shen Granule and the curative effect of Yi Shen Granule on ongoing pathological changes of CRF was studied. According to the data of CRF rats in weight, water wastage, hemanalysis(RBC、HGB、HCT、MCV、MCH), urinalysis(volume, specific gravity, pH, proteinuria), blood serum analysis(BUN、Cre、ALB、TP), kidney weight coefficient and kidney morphology ( the grade of expansile renal tubule and the diameter of glomerulus ),the pharmacological effect of Yi Shen Granule could be ascertained.

实验选用0.75%腺嘌呤饲喂法致大鼠慢性肾衰模型和5/6肾切除法致大鼠肾衰模型，考察益肾颗粒对慢性肾功能衰竭进行性病变的影响，以造模动物一般状况观察、血液学指标包括红细胞计数、血红蛋白、红细胞压积、平均红细胞体积、平均红细胞血红蛋白(RBC、HGB、HCT、MCV、MCH)，尿液指标(尿量、比重SG、pH值、尿蛋白)、血清生化学指标包括尿素氮、肌酐、白蛋白、总蛋白(BUN、Cre、ALB、TP)、脏器解剖和病理观察指标(肾小管扩张分级评分和肾小球径长)做为判定依据。

If on grounds of our real, divinely ordained, superiority a Christian pathologist thinks it right to vivisect, and does so with scrupulous care to avoid the least dram or scruple of unnecessary pain, in a trembling awe at the responsibility which he assumes, and with a vivid sense of the high mode in which human life must be lived if it is to justify the sacrifices made for it, then (whether we agree with him or not) we can respect his point of view.

如果一个信仰基督教的病理学家，基于我们现实存在的、上帝赐与的优越性而认为活体解剖是对的，并在进行活体解剖时小心谨慎避免造成最微小的不必要的痛苦，对肩上的责任抱着战战兢兢的敬畏态度，而且清楚地意识到为了证明为人的生命做出牺牲是值得的，人必须以高尚的方式生活，那么(不论我们是否同意他的观点)我们便能够尊重他的观点。

After radiation, dog brain existed micro-changes injury. DWI is a most sensitive functional imaging technique in detecting hydrone diffusion capability changes. It can discover and quantitatively analyze the micro-changes preceding anatomy imageology by measuring the irradiated tissue ADC value.

核辐射损伤犬脑在解剖影像学尚未出现异常改变之前已存在微观的病理变化；DWI是一种极其敏感的探测水分子弥散能力变化的功能性成像技术，能够先于解剖影像学发现核辐射损伤犬脑的微观病理改变并通过测量辐射损伤组织的ADC值加以定量分析，有重要的临床应用价值。

Through simulation of the real process of thomcolumbar burst fracture and use of modem dynamics techniques, the present study was (1) to investigate the kinetic relationship between structural damage and impact energy absorption and dynamics mechanism of thoracolumbar burst fracture by quantitative analysis of various injured segments;(2) to explore the instability mechanism of L1 vertebral burst fracture and its injury threshold by three-dimensional analysis of the injured segment with stereophotogrammetry in combination of transient physical parameters, anatomy and image;(3) to explore the corresponding relationships between impact energy, geometry parameters and biomechanics by geometry and biomechanical analysis of thoracolumbar burst fracture, which may provide an objective standard for evaluation of spinal injury severity and experimental evidence for adoption of biomechanical treatment in clinic;(4) to evaluate the fixation effect of different instruments and the effect of intervertebral bone graft on segment fixation by analysis of the threedimensional stability of different internal fixation instruments and their decompression of the spinal canal, which may provide experimental evidence for therapeutical selection for thoracolumbar burst fracture in future; and finally to investigate the effect of various instrument fixation on dynamical characteristics by comparison and quantitative analysis of frequency and amplitude responses, which may provide certain theories and experimental evidence for application of vibration test to judge the stability of the spine.

本研究从胸腰段脊柱爆裂骨折发生的实际过程出发，以现代动力学检测及计算机多通道高性能数据采集分析系统等高新技术为基础，实时量化分析损伤节段的工程参数，揭示了结构破坏与能量吸收的变化规律，探讨了胸腰段脊柱爆裂骨折的瞬态损伤机制；利用三维立体摄像技术，对不同损伤程度的节段进行三维运动分析，结合瞬态物理参数、影像学和病理解剖，明确了〓椎体爆裂骨折的失稳机制及损伤阈值；通过对胸腰椎爆裂骨折的几何学变化及生物力学分析，明确了撞击能量与几何参数、几何参数与生物力学的相应关系，为评判脊柱损伤程度提供了客观标准，为治疗中采取适宜的生物力学方法提供了实验依据；通过对比分析不同内固定器械的三维稳定性和对椎管的减压作用，评价不同器械的复位固定作用，同时比较椎体间植骨对节段固定作用的影响，为今后临床胸腰段脊柱爆裂骨折的治疗选择提供依据；利用振动测试与分析技术，比较及量化分析了不同致伤状况的频幅响应特征，比较分析了各种器械固定对动力学特性的影响，为今后临床建立基于振动测试与分析技术判断脊柱稳定性的诊断方法，提供了一定的理论和实验依据。

Methods Sixteen cases of pericardial tamponade death were diagnosed by autopsy. Their clinical and pathological records were reviewed.

收集经尸体解剖确诊为因心包填塞死亡的16例病例，回顾分析其尸检病理资料及临床资料。

ABSTRACT Objective To discuss the clinical pathologic features and differential diagnosis of mixed germ cell sex cord stromal tumorwith malignant variant of germ cell tumor Methods The clinical pathologic datum and immunophenotype were studied in the case of ovary MGCSCST with malignant variance of germ cell tumor Results The patient's genital anatomy and female phenotype were normal,karotypes was 46xx with uterogestation The tumor tissue consisted of mixed germ cells and sex cord stromal cells with evident malignancy of mixed germ cells There was no atypical structure of gonadoblastoma in tumor tissue Conclusion MGCSCSST has complex morphosis,thus,to prevent misdiagnosis,more samples should be collected and more slices be cut The patient may have prognosis malo when there are high malignant variants of mixed germ cells in tumor tissue

目的 探讨混合性生殖细胞性索间质肿瘤(mixed germ cell sex cord stromal tumor，MGCSCST)伴恶性生殖细胞肿瘤变异型的临床病理特点及鉴别诊断。方法卵巢MGCSCST伴恶性生殖细胞肿瘤变异型的病例进行临床病理特征和免疫表型分析。结果患者生殖器的解剖结构和女性表型正常，染色体组型是46xx，足月妊娠。肿瘤组织由混合性生殖细胞和性索间质肿瘤构成，混合性生殖细胞有显著的恶性特征。瘤组织中没有典型的性腺母细胞瘤结构。结论 MGCSCST有复杂的形态结构，因此更多的取材和切片可以防止误诊，当肿瘤组织中的混合性生殖细胞有高度恶性变异时，患者预后不良。卵巢肿瘤；生殖细胞性索间质肿瘤；免疫组织化学

Methods: Integrated and disrepaired skins in the rats were smeared with Salicylic AcidPhenol Liniment by the maximum tolerated dose only. The toxic reaction of the animals were observed and recorded continuously from the beginning of using the drug to 7 days, and evaluated by using the general standard of the reaction of skin stimulation in pharmacology. Animals were executed by taking off acanthi and blood was collected to check up the periphery blood routine and serum biochemistry at the end of the observation of the rats. And after the dissection, the pathological change of main visceras, such as heart, brain, liver and kidney were observed with naked eye and pathological slices. The data of this experiment was used to calculate the value of LD50 by using Bliss rule.

观察大鼠完整皮肤及破损皮肤一次性涂抹最大耐受量的小儿水杨酸苯酚搽剂所产生的毒性反应情况，从给药0时起至7 d连续观察记录动物的急性毒性和45 d连续的长期毒性反应，以皮肤刺激反应标准进行评分作毒理等级评价；对存活动物在观察结束时进行高位脱椎处死采血检测外周血常规和血清生化，解剖后裸眼和病理切片观察心、脑、肝、肾等主要脏器的病理变化。

The rabbits were immobilized according to the standard of X_knife before CT scanning. The interrelation of the silica gel tube and bony structures was analyzed, a nerve segment was selected, which could be localized according to the related bony structures as irradiation target. A radiosurgery treatment planning was performed on the selected nerve segment, its changes of pathology and ultrastructure were observed. Results: Base on the dissection, the rabbits' sciatic nerve was composed of the seventh lumbar nerve and first and second sacral nerves.

通过解剖分析兔坐骨神经主干的解剖位置和行径，选择照射靶点，放置硅胶管进行标记，按X_刀标准行CT扫描，从CT图像上分析硅胶管与荐骨和髂骨的位置关系，确定可以用骨性结构定位的神经段作为照射靶点，利用立体定向技术单次大剂量照射坐骨神经，观察其病理及超微结构变化。

The mechanics of pathogenesis and the method of prevention and treatment of the syndrome of third lumbar transverse process have been studied in anatomy, pathology and clinics.

本文从解剖、病理和临床等方面对第三腰椎横突综合征的发病机理和防治方法进行了研究。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。