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Methods: The asthmatic guinea pig model was established with the ovalbumin challenge methods. Forty-eight guinea pigs were randomly divided into six groups: normal control group,asthma model group,DXM treated group,three dose groups of Jianerqiangshen electuary. The effects of relieving asthmatic attacks were observed,and pulmonary morphology and ultramicrostructures were observed too.

采用卵蛋白致敏法制备豚鼠哮喘模型,将豚鼠随机分为6组,即空白对照组、模型组、阳性对照组、中药3个剂量组,分别观察各组引喘潜伏期、支气管和肺组织的病理及超微结构变化。

We discuss the clinical presentation, imaging and neuropathological results and relate our findings to embryological data and the existing literature.

本文讨论了临床表现、影像学表现及神经病理检查结果,并涉及胚胎学资料及现有的文献资料。

Furthermore, pulmonary arterial encasement implies microscopic vascular invasion which is related to a poor prognosis.

除此之外,影像上看到一个病灶内有肺动脉被包埋压迫时可以预知病理切片下可看到血管内侵犯,这是个不良预后的象徵。

Objective To explore pathological changes of optic nerve in experimental autoimmune encephalomyelitis.

目的 研究实验性自身免疫性脑脊髓炎的视神经病理改变。

Acute disseminated encephalomyelitis:A followup study of 40 adult patients[J].

实验性变态反应性脑脊髓炎的病理研究[J]。

Objective To investigate the histopathalogical features of acute and chronic experimental allergic encephalomyelitis with monkeys.

目的 探讨急、慢性猴实验性变应性脑脊髓炎的病理特点。

Results: The tHey and blood fat level in blood plasma and expression of MCP-1mRNAof aorta on model group is obviously higher than that of control group (P<0.05);the result of immunohistochemistry shows that the expression of VCAM-1 and MMP-2enhanced, Bcl-2 is lower; aorta slice shows endarterium discontinuation, strippingpartly, smooth muscle cell arrange puffly and chaotic, infiltration of lipoid ofdifferent degree are observed in aorta wall, pathological changes suffusion, morexanthoma cell, plaque protrude lumens. The they and blood fat level in blood plasmaand expression of MCP-lmRNA, VCAM-1, MMP-2 of aorta on intervention group aremuch lower than that of model group (P<0.05); Bcl-2 of intervention group isstrengthened, and the pathomorphology and immunohistochemistry of aorta showpathological changes are slighter than model group.

结果:模型组,血浆中同型半胱氨酸浓度、血脂水平、主动脉MCP-1mRNA表达显著高于正常对照组(P<0.05),免疫组化示主动脉内皮细胞VCAM-1、MMP-2表达增强,Bcl-2表达降低;主动脉切片发现动脉内膜不连续,部分剥脱,平滑肌细胞排列疏松、紊乱,主动脉壁均见到程度不同的脂质浸润,其病变弥漫,泡沫细胞较多,可见斑块突出管腔;干预组,血浆中同型半胱氨酸含量、血脂水平显著低于对照组和模型组(P<0.05),主动脉MCP-1mRNA、VCAM-1、MMP-2表达显著弱于对照组和模型组(P<0.05),Bcl-2表达增强(P<0.05),主动脉病理形态学和免疫组织化学检测示病变轻于模型组。

Of cause, it is clear that the abnormal increase of the endolymph formation and/or its decreased absorption is the main pathophysiological changes of the disease.

这里强调了两点:一是病因和发病机理仍未阐明;二是肯定地说,其主要的病理生理变化是内淋巴液产生过多和/或吸收过少。

β-endorphin participates in HIE pathophysiologic process and naloxone has certain therapeutic effects in the treatment of HIE.

β-内啡肽参与 HIE的病理生理过程,纳洛酮对 HIE仍有一定治疗作用。

Measured myocardial enzymology, the area of myocardial infarct, apoptosis and the difference of HE stain.

测定清醒大鼠心肌酶学、心肌梗死面积、细胞凋亡和组织病理HE染色的变化。

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