病理学

Objective The nature of myoid/myofibroblastic differentiation in dermatofibrosarcoma protuberans and its clinical and pathological significance were studied.

目的 探讨隆突性皮纤维肉瘤中肌样／肌纤维母细胞性分化的本质及其临床病理学意义。

A disorder due to a similar molecular basis, myotonic dystrophy 1 (DM1), is known to have white matter hyperintensities on cranial MRI.

另一种有类似分子病理学基础的疾病：萎缩性肌强直(DM1)患者的核磁共振成像也有白质高信号。

Neoplasma/pathology ; Ki67; cell cycle ; Proliferation PCNA antigen ; flow cytometry

肿瘤/病理学； Ki67；细胞周期；增殖细胞核抗原；流式细胞术

The mouse was carried out half nephric duct ligation to induce the renal interstitial fibrosis animal model,afterwards,to set up three groups,control group,sham operation group(intragastric administration with normal sodium according to 10ml/kg weight),treatment group...

采用小鼠单侧输尿管结扎法诱导肾间质纤维化的动物模型，用盐酸青藤碱治疗，并设对照组、假手术组(小鼠每日按10m l/kg体重用生理盐水灌胃，直至治疗结束)、治疗组(选用正清风痛宁缓释片按每日30mg/kg体重给小鼠灌胃，连续3周，)，检测血尿素氮、血肌酐、血清层粘连蛋白、纤维连接蛋白的含量，免疫组化法测肾脏组织转化因子β1(TNF-β1)的表达并进行肾脏病理学的观察。

Results The model showed serious edema, proteinuria, hypoproteinemia, and hyperlipidemia. Podocytes were swollen and mesangial cells developed mild hyperplasia at the end of the fourth week. The nephric tubule atrophied at the end of the eighth week accompanied with adhesion between glomeruli and Bowman's capsule. Glomeruli sclerosis of mild or medium degree was observed at the end of the twelfth week with obvious lymphocyte infiltration in the renal interstitium as well as the formation of collagen fibers.

结果 该模型表现为严重水肿、大量蛋白尿、低蛋白血症和高脂血症；病理学检查显示，4周末肾小球足细胞肿胀，系膜细胞轻度增生；8周末有球囊粘连，肾小管上皮细胞萎缩；12周末部分肾小球节段性轻、中度硬化，间质内有明显灶性淋巴细胞浸润，并有轻度纤维化。

After the experiment the nephridial tissues were made into histological sections, the pathological changes were observed through microscope.

实验结束后，取各组兔肾脏制成切片，HE染色后镜下观察肾组织病理学变化。

NB can make liver, brain, spleen and nephridial tissue pathology damage, to refrain theactivity of liver mixed function oxidase, induce oxidative stress, effect tissue enzymatic activity,destroy organism antioxygen defence system and function of clean up free radical, to cause proteinoxidation damage, to educe toxic action.

综上所述，NB可以造成肝、脑、脾、肾组织的病理学损伤，抑制肝内混合功能氧化酶的活性，诱导氧化应激，影响组织酶活性，破坏机体抗氧化防御系统及清除自由基功能，引起机体蛋白质氧化损伤，进而发挥其毒性作用。

Objective To investigate the effects of Tripterium Regelii on pathology of nephritic mice.

目的 研究东北雷公藤对肾炎大鼠肾脏组织病理学的影响。

The pathogical changes and the clinical results of the involved kidneys in this studY lead the authors to believe that primary nephrectomy would be much preferable than preliminary nephrostomy in those pateints.

根据脓肾造瘘后患肾的转归和病理学改变，作者认为对于单侧上尿路结石并脓肾患者的治疗，一期切除病肾应作为首选。

Chapterl Establishment of the chronic and pressure-induced SD rat models for acoustic neurinomas Object To establish the chronic and pressure-induced SD rat models of acoustic neurinomas for the purpose of further experimental research on acoustic neurinoma related electrophysiology, function and pathomorphology of facial nerves and cochlear nerves.

第一章 SD大鼠听神经瘤慢性压力模型的建立目的建立SD大鼠听神经瘤慢性压力模型，为听神经瘤所致面、听神经电生理、功能及病理学改变的研究奠定基础。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。