病变

Methods The TEOAE results of 46 ears with middle ear disorders(hearing loss less than 30 dB)which confirmed by otoscope、pure tone audiometry、acoustic immittance measures,and 28 normal ears as control were analyzed.The 46 ears classify into three groups on the basis of hearing threshold level,and classified into four groups on the basis of different disorders.

选择经耳镜检查、纯音听阈及声导抗测试确诊为中耳病变，纯音气导听阈不超过30 dB HL的46只病变耳及对照组正常28耳进行TEOAE测试，病变46耳分别按不同听阈水平及不同病变分组，并对其结果进行分析比较。

Results (1)The permillage of myocyte apoptosis in infarct area in elder patients with sudden death caused by AMI was significantly higher than that in control group(663.00‰±117.12‰ vs 34.30‰±20.68‰,P＜0 .01).However the permillage of myocyte apoptosis in 1-vessel,2-vessel,and 3 - vessel disease were 514.28±165.12‰,564.38‰±102.33‰ and 668.25‰±127. 19‰,respectiverly,significantly higher as compared to control group(All P＜ 0.01).But no significance was found among the three groups.(2)The size of DNA f ragment about 180～200 bp was found only in those patients with two and three ve ssels involoved.(3)The electron microscope showed the characteristics of myocyte apoptosis episodes,the others showed the characteristics of necrosis.

结果 TUNEL法发现，猝死者梗死区的心肌细胞凋亡千分数老年组(663.00‰±117.12‰)明显高于正常对照(34.30‰±20.68‰)(P＜0.001)；心肌细胞凋亡千分数在冠脉1支病变者(514.28‰±165.12‰)＜2支病变者(564.38‰±102.12‰)＜3支病变者(668.25‰±127.19‰)，虽然均明显高于正常对照(均P＜0.01)，但三组之间比较则无统计学上的差别(均P＞0.05)；冠脉2～3支病变者梗死区的心肌细胞DNA电泳可见相差约180～220 bp的阶梯片段；电镜发现猝死者梗死区内的心肌细胞核膜完整、染色质浓集、电子密度增加的凋亡特征，有的则出现核膜破裂、染色质溶解成碎屑的坏死现象。

Abstract］ objective to assess a new imaging technique,optical coherence tomography,for the diagnosis of central serous choroidoretinopathy.methods forty-five cases (45 eyes) of csc were examined by ophthalmoscopy,binocular indirect ophthalmoscopy and oct.some patients were monitored by oct.results in images of oct in 45 eyes of csc,42 eyes showed serous neurosensory detachement,2 eyes appeared retinal pigment epithelial detachement and 1 eyes combined neurosensory detachement with pigment epithelial detachement.monitoring images of oct in 9 eyes revealed absorption of serous fluid and decrease of neurosensory detachment.conclusion oct is potentially useful as a new and noninvasive diagnostic technique for quantitative examination of patients with csc and objectively monitoring the clinical course of the serous retinal detachement in this disease.

摘要］ 目的评价光学相干断层成像(optical coherence tomography，oct )对中心性浆液性脉络膜视网膜病变的临床诊断价值。方法对45例(45眼)中心性浆液性脉络膜视网膜病变患者散瞳后分别进行直接检眼镜、双目间接检眼镜、oct 检查。9例复查时再次进行oct检查。结果 45眼中心性浆液性脉络膜视网膜病变的oct 图像，42眼表现为单纯神经上皮层脱离，2眼为单纯色素上皮层脱离，1眼同时存在神经上皮层脱离和色素上皮层脱离。9眼复查的oct通过测量脱离高度的降低可观察到液体的不同程度吸收。结论 oct 是一种新的、无损伤性的、非接触性的、并能定量的检查方法，能明确中心性浆液性脉络膜视网膜病变的脱离部位，并能进行定量的追踪观察。

The 46 ears classify into three groups on the basis of hearing threshold level,and classified into four groups on the basis of different disorders.Results The amplitude and reproducilbiity decreased as the hearing loss increased.

选择经耳镜检查、纯音听阈及声导抗测试确诊为中耳病变，纯音气导听阈不超过30 dB HL的46只病变耳及对照组正常28耳进行TEOAE测试，病变46耳分别按不同听阈水平及不同病变分组，并对其结果进行分析比较。

The diabetes foot is the foot department pathological changes, that is nerve pathological changes , blood vessel pathological changes and infection;Once the foot department external injury or pathological changes , the foot department will become ulcerate easily even get bad putrefaction to cut a limb , then influence the work , family and social level etc.

前言糖尿病足是指足部产生神经病变、血管病变及感染的足部病变，一旦足部外伤或病变易形成溃疡甚至坏疽而截肢，进而影响到工作、家庭、社会层面等（Giurini ＆Lyons， 2005；Stein， Yaacobi，＆ Steinberg， 2003林、陈，2006）。

CT perfusion images can visually show different traits of Hemodynamics of hepatic Benign and Malign pathology; No matter what background, various parameters of hepatic tissue around malign lesions had significant difference with far-end liver tissue, while various parameters of hepatic tissue around benign lesions had no significant difference with far-end liver tissue; Allopatric efficiency of hepatic Malign pathology distinctly went up with hepatocirrhosis background;Various parameters of hepatic Benign and Malign pathology had no significant difference and differential significance were no significant.

灌注参数图像能直观显示肝脏良、恶性占位性病变血流动力学的不同特点；无论在何种背景下，恶性病变灶周组织与远端肝组织各同种参数间有显著差异，而良性病变灶周组织与远端肝组织各同种参数间无显著差异，以上特点可以鉴别肝脏占位性病变的良、恶性；肝硬化背景下，恶性病变的发生率明显增高；正常肝组织背景下，良、恶性占位病变组织灌注参数间无显著差异，鉴别诊断意义不大。

Bronchoscopic results showed exudative lesions in 38% of the cases,granulomatous lesions in 9%,cicatricial lesions in 26%, ulcerative lesions in 17%, and normal-like demonstrations in 11%. Positive results were found in 8 out of 50 by sputum acid-fast staining, 73 out of 86 by bronchoscopic brushing smears, and 17 out of 56 by bronchial biopsies.

纤支镜检查示38％的病例有炎症浸润型病变，9％有增殖型病变，26％有狭窄闭塞型病变，17％有溃疡型病变，11％大致正常。56例痰涂片行抗酸染色者中8例阳性，86例行纤支镜刷片检查者中73例阳性，56例行活组织检查者中17例证实为结核。

Bronchoscopic results showed exudative lesions in 38% of the cases,granulomatous lesions in 9%,cicatricial lesions in 26%, ulcerative lesions in 17%, and normal-like demonstrations in 11%. Positive results were found in 8 out of 50 by sputum acid-fast staining, 73 out of 86 by bronchoscopic brushing smears, and 17 out of 56 by bronchial biopsies.

纤支镜性功能检查示38％的病例有炎症情人浸润型病变，9％有增殖型病变，26％有狭窄闭塞型病变，17％有溃疡型病变，11％大致正常。56例痰涂片行抗酸染色者中8例阳性，86例行纤支镜刷片性功能检查者中73例阳性，56例行活组织性功能检查者中17例证实为结核。

Theurinary IL-6 level positively correlated with density of glomerular matrix membrane, global sclerosis, fiber or fibrocellular crescents and interstitial fibrosis (p. 05). According to the degree of density of glomerular matrix membrane and interstitial fibrosis, urinary Col-IV level had better correlation than urinary TGF-betal and IL-6 levels.In IgAN, Col-IV showed increased expression in diseased renal tissue whereas the site of expression of TGF-betal was mainly localized within the cytoplasm of tubular epithelial cells. Interstial expressionwas also present but glomerular TGF-betal expression was found only in patients with heavy mesangial proliferation. There was a significant correlation between glomerular positivity for Col-IV and severity of histological damage. There was also a significant correlation between positivity for TGF-betal and Col-IV in the tubular epithelial and interstitial lesions. In contrast, there was no ralationship between glomerular positivity for TGF-betal and severity of histological damage.The urinary TGF-betal level paralleled tubular TGF-betal expression.

结果 ①IgAN患者尿TGF-β1、IL-6、Col-Ⅳ水平较健康人明显增高(P＜0.01)，该变化与血中的浓度无关(P＞0.05)；②尿TGF-β1水平与小管间质TGF-β1阳性表达呈正相关(P=0.000)，而与小球TGF-β1阳性表达无关(P＞0.05)，尿Col-Ⅳ水平与小球和小管间质Col-Ⅳ阳性表达均呈良好的相关性(P＜0.01)，还与小管间质TGF-β1阳性表达呈正相关(P＜0.05)：③小球Col-Ⅳ阳性表达与肾组织慢性病变密切相关(P＜0.05)，小管间质Col-Ⅳ和TGF-β1阳性表达均与肾小管间质病变呈良好的相关性(P＜0.01)，而小球TGF-β1阳性表达与肾组织损伤无关(P＞0.05)；④尿TGF-β1、Col-Ⅳ水平与肾小球基质基底膜面密度、小管间质病变呈正相关(P＜0.01)，与小球内细胞数呈负相关(P＜0.05)，该结果与其在组织中的表达一致；尿IL-6水平浙江大学硕士学位论文尿TGF一B一、IL一6和Col一IV在IgA肾病中的应用价值与基质基底膜面密度、球性硬化、纤维或细胞纤维新月体所占肾小球百分数及小管间质病变均有显著的相关性(F.05)；在轻度肾病理损伤时，尿'l'G卜pl、I卜6、Col一IV水平即升高，而尿Col一W在反映细胞外基质积聚和间质纤维化程度上比尿TGF一pl和IL一6有更好的相关性。

RESULTS :① The left anterior descending branchwas most likely to be damaged;②The specificity between the wall-motion abnormality in A,AS,Apex an d single LAD disease was great (P.05);LAD and left circumflex artery infarcts could lead to AL and I regional wall-motion abnormalities respective l y;contractile function hypokinetic of the single I segment was mostly connected with LCX and right coronary artery injuries;patients with whole left ventricul ar contraction function hypokinetic always suffered from the three-vessel disea se .

结果：①冠状动脉梗塞后左前降支受累最为多见(45%)；②LAD单支病变与前壁、前间隔及心尖部室壁运动异常有关(P.05)。LAD与左回旋支病变，主要为前间隔和下壁运动异常；而单纯的下壁室壁运动异常多为左旋支与右冠状动脉病变引起。3支病变造成心肌运动普遍减低，且以侧壁及前侧壁的室壁运动异常则更为显著(P.05)。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。