病变

The vascular adventitia is involved in the pathological process of intimal hyperplasia, and oxidative stress caused by increased NADPH oxidase activity may be one of the mechanisms.

血管外膜参与了内膜病变形成的病理过程；NADPH氧化酶活性升高导致的氧化应激可能是外膜损伤致内膜病变的机制之一。

The items of microalbuminuria which could be inspect in clinic presently: Microalbuminuria, alpha-1–microglobulin (a_1-MG), transferin, beta2-microglobulin(β_2-MG), Urine IgG, alexin C3, retinol binding protein and so on.

根据有无尿微量白蛋白及尿蛋白水平将糖尿病患者分为3组，并将所有患者按国际公认诊断标准分为冠心病组、高血压组、脑血管病变组，下肢动脉硬化病变组。

Results Positive CAG:58cases（75%）;Negative CAG:19cases（25%）;Single-branch Pathology18cases;Double-branch Pathologies:40cases;Many-branch Pathologies:19cases;STc extension:25cases;S-wave deepeness:21cases;U-wave inverˉsion:2cases.

结果 冠状动脉造影阳性58例（75%），阴性19例（25%），单支病变18例，双支病变40例，多支病变19例，STc延长25例，S波加深21例，U波倒置2例。

Results Positive CAG:58cases（75%）;Negative CAG:19cases（25%）;Single-branch Pathology18cases;Double-branch Pathologies:40cases;Many-branch Pathologies:19cases;STc extension:25cases;S-wave deepeness:21cases;U-wave inverˉsion:2cases.

结果 冠状动脉造影阳性58例（75%），阴性19例（25%），单支病变18例，双支病变40例，支病变19例，STc延长25例，S波加深21例，U波倒置2例。

The cutoff value of E2/E6, used to distinguish the pure episomal form from a mixed form of episomal and integrated HPV16 DNA, was 0.81 in the multiplex real-time PCR test. c） HPV16 existed as episomes in most of the CIN Ⅰ lesions, and 42.9% of them had mixed episomal/integrated HPV16. The integrated form of HPV16 constituted the majority in most of the CIN Ⅱand CIN Ⅲ cases. In squamous cervical carcinomas, the HPV16 was mostly integrated into the host chromosome. d） The rate of HPV16 integration was associated with the degree of cervical lesions and the rate increased with the progression of cervical disease, e） The rate of pure integrated HPV16 in stage Ⅱ and Ⅲ（88%） was higher than that in stage Ⅰ（33.3%）. Conclusions: a） Multiplex real-time PCR is a rapid and sensitive method for detection of the integration state of HPV16 DNA. b） The integration of HPV16 DNA is a very early event in the development of cervical cancer and may act as an activation mechanism for progression from preinvasive to invasive cervical cancer, c） The pure integrated HPV16 in cervical cancer may be a useful prognostic indicator.

HPV—16E2、E6标准曲线相关系数均为1.00，扩增效率均在95％以上：2）确定0，81作为多重实时PCR区分游离型和混合型HPV-16的界值、3）CINⅠ中HPV—16大多以游离方式存在，但仍有整合的发生（42，9％）；CINⅡ和CINⅢ中HPV—16以混合型为主：浸润癌中以整合型HPV—16为主。4）HPV-16整合发生率与不同程度的宫颈病变有关，并且随着宫颈病变级别的升高HPV-16整合发生率呈上升趋势-5）Ⅱ＋Ⅲ期宫颈癌中整合型HPV—16所占比例显著高于Ⅰ期宫颈癌结论：1）多重实时定量PCR是一种敏感性高、简便快速的HPV—16病毒存在状态的检测方法2）HPV-16整合是宫颈癌变的早期事件，与宫颈癌前病变的进展有关。3）宫颈癌中整合型HPV—16的发生可能具有预后价值

Results: Lesion can occur in any grade of the branches of the parotid duct, the incidence of abnormal changes was highest in the terminal ductules. The lesion has a tendency to develop from the terminal ductules to the main ducts.

结果：各级腮腺导管均可发生病变，以末梢导管病变发生率最高，病变有从末梢导管向主导管发展的倾向。

PICAS was extremely difficult in coronary complex disease,sever or closed lesions and longer lesion but success rate was high when technical operation was very skilled.

冠脉复杂病变，重度或闭塞病变，以及长段病变的PICAS的难度大，但技术操作熟练，成功率也高。

Effective different prevent measures should be adopted in different aged patients with different clinical and damaged coronary arterial characteristics.The place of damaged artery is unlike in different ages patients.LCX and RCA diseases in the elderly patients occur more frequently than in young and middleage patients.

不同年龄段冠心病患者有不同的临床和冠状动脉病变特点，不同年龄人群应采取有针对性的冠心病防治措施；不同年龄人群冠脉病变血管部位不同，普通老年人和高龄老年人LCX和RCA病变所占比例较大。

Finally the pathological change implicates the lung section bronchial tube pulmonary alveolus fills in the cleaning solution cd3 t cell obviously to be lower than does not have the lung section group which the pathological change implicates, cd4 t cell, cd4/cd8, the nk cell obviously to be lower than the opposite side lung section group which the pathological change has not implicated.

结果 病变累及的肺段支气管肺泡灌洗液中cd3t细胞明显低于没有病变累及的肺段组，cd4t细胞、cd4/cd8、nk细胞明显低于病变没有累及的对侧肺段组。

Men with histologically confirmed BE and HGD (33), IMC (16), underwent CBE-EMR from August 2003 to August 2008. The mean BE segment length was 3.2 cm (median 2, s.d. 2.2); 26 patients had short-segment BE, and 30 had visible lesions.

这些患者BE病变的平均长度为3.2厘米（中位数2，标准差2.2）； 26名患者BE病变长度较短，30名患者存在可见BE病变。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。