疱疹的

Halford joined SIU's faculty in 2007, but has been researching the herpes simplex virus since 1992, first focusing on HSV-1, which causes cold sores and sometimes leads to genital herpes.

哈尔福德于2007年加入萧的教师，但自1992年以来一直在研究单纯疱疹病毒，首先侧重于单纯疱疹病毒1，这会导致唇疱疹，有时会导致生殖器疱疹。

Q2. I visited a sex worker at a massage parlor. She performed unprotected oral sex on me. What are my chances of contracting herpes?

问题2：我去找了一家按摩房的性服务提供者，她为我提供了无保护措施的口交服务，我感染生殖器疱疹的机会是多大？

For most viruses,there is aneed for antimicrobials that target unique viral molecular properties.Acycloviris one such drug.It is activated into ahuman herpesvirusDNA polymerase inhibitor exclusively by HHV kinases and,thus,does not suppress other viruses.Here,we show that ACV suppresses HIV-1in HHV-coinfected human tissues,but not in HHV-free tissue or cell cultures.However,addition of HHV-6-infected cells renders these cultures sensitive to anti-HIV ACV activity.We hypothesized that such HIV suppression requires ACV phosphorylation by HHV kinases.Indeed,an ACV monophosphorylated prodrug bypasses the HHV requirement for HIV suppression.Furthermore,phosphorylated ACV directly inhibits HIV-1reverse transcriptase,terminating DNA chain elongation,and can trap RT at the termination site.These data suggest that ACV anti-HIV-1activity may contribute to the response of HIV/HHV-coinfected patients to ACV treatment and could guide strategies for the development of new HIV-1RT inhibitors.

对大多数病毒而言，都需要有针对其分子特性的靶向杀毒剂阿昔洛韦就是这样一种靶向药物在人疱疹病毒酶的特定作用下，阿昔洛韦被激活成为人疱疹病毒DNA聚合酶抑制剂，因此不能再抑制其它的病毒我们的研究发现阿昔洛韦在共感染人疱疹病毒的组织中可以抑制HIV-1，但在无人疱疹病毒感染的组织或细胞中无此作用然而，加入人疱疹病毒-6感染的细胞却使得其对抗HIV的阿昔洛韦变得敏感我们推测这种抑制作用依赖于人疱疹病毒酶导致的阿昔洛韦磷酸化实际上，单磷酸化的阿昔洛韦前体药物无需人疱疹病毒的参与即可抑制HIV此外，磷酸化的阿昔洛韦能直接抑制HIV-1逆转录酶，将其阻止在终止位点，从而终止DNA链的延长这些结果提示阿昔洛韦的抗HIV-1活性决定了艾滋病病毒/人疱疹病毒共感染的患者对阿昔洛韦的治疗反应，也有助于开发新的HIV-1逆转录酶抑制剂

Grouped vesicles on an erythematous base occurring unilaterally are indicative of herpes zoster. It is a common early or initial manifestation of HIV infection.

单侧发生的红斑基底上的群集水疱是带状疱疹的指征，也常是 HIV 感染的早期表现。

Like other alpha herpesvirus such as herpes simplex virus type I, varicella-zoster virus and bovine herpesvirus type I, PRV also has some typical characteristics of alpha herpesvirus, including latency and neurotropism.

与同属α—疱疹病毒亚科的人单纯疱疹病毒、水痘-带状疱疹病毒和牛疱疹病毒Ⅰ型等一样，PRV具有潜伏感染和神经嗜性等α—疱疹病毒的典型特征。

Although only 4% of patients reported a history of genital herpes, overall weighted HSV-2 seroprevalence was 25.5%(95% confidence interval, 20.2%- 30.8%). Of the 1,387 seropositive subjects, only 12% knew they were infected.

尽管患者中，只有4%有生殖器疱疹的历史，总加权的HSV-2的血清普遍性为25.5%（95%信赖区间，20.2%-30.8%），1，387个血清阳性的受试者中，只有12%知道他们受到感染。

You are not able to use the issue, I remember the first three months of pregnant women have herpes to the baby can not be easily teratogenic.

你现在不是能不能用药的问题，我记得前三个月得疱疹的孕妇的宝宝是不能要的，容易致畸。

Results No significant differences in prodromes, herpes area and neuralgia were seen between KDHZ and NKDHZ, but the differences in places where the herpes occurred except chest, back, waist and abdomen were significant between KDHZ and NKDHZ.

采用病例对照研究，重点比较KDHZ与NKDHZ两组患者临床特点与治疗反应的不同，从而了解肾脏病及其用药对带状疱疹的发生、发展、临床表现和治疗等方面的影响。

In the past few years, he has lost much of his hair, and a recent attack of shingles had left some scabs on his forehead, but his face was as serene as I'd ever seen it.

这几年来，他掉了许多头发，最近一次带状疱疹的发作在他前额上留下几块疤，但他的神色却比以往越发安详宁静。

Safe-Pak? solid bleached sulfate paperboard from International Paper (www.internationalpaper.com) and a clear blister of recycled PET.

安全白田？固体漂白硫酸盐纸板从国际纸业（ www.internationalpaper.com ）和一个明确的疱疹的回收PET 。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。