疱疹

This is a relatively new drug for neuropathic and post-herpetic pain.

这是一类与神经痛和后发性疱疹性疼痛。

Results obtained by 〓-fluorescent probe and morphological observation consistently showed that neurotoxic effects of MSG could be corporated with neurotropic herpesvirus hominis .

亲神经性人疱疹病毒协同MSG对幼鼠和成鼠的神经毒性作用。

Herpes simplex virus HSV -based vectors have primarily been developed for neuronal gene delivery , taking advantage of the virus 39 natural neurotropism .

单纯疱疹病毒为基础的载体主要是发达国家的神经元基因传递，利用病毒的自然神经性。

A: Common causes of post-transplant infections of the central nervous system within the first 6 months include Listeria monocytogenes, many nocardia species, herpesviruses, and Toxoplasma gondii.

最常见的移植后6个月内中枢神经系统感染的原因包括单核细胞增多性李斯特菌、诺卡氏菌、疱疹病毒、鼠弓形体。

Polymerase chain reactiondetection of herps simplex virus type Ⅱ in prostatic fluid of 74 cases of chronic nonbacterial prostatitis was carried out and in 41 normal subjects as controls.

为探讨病毒性前列腺炎的病原学，采用多聚酶链反应技术对74例慢性非细菌性前列腺炎的前列腺液进行单纯疱疹病毒Ⅱ型检测。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速，应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等，其中自杀基因被认为是最有前景的基因治疗方法，它又称病毒介导的酶／药物前体疗法，是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中，该基因表达的产物可将无毒的药物前体转化为毒性药物，从而选择性杀伤该肿瘤细胞，常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因，前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物，然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷，作为DNA合成链的终止剂和DNA合成酶的抑制剂，干扰细胞DNA的合成；后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶（5-FC）脱氨成为5-氟尿嘧啶（5-FU），然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸（5-FUTP）和5-氟-2′脱氧尿嘧啶-5′磷酸（5-FdUTP），5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成，5-FdUTP则作用于胸苷合成酶，导致TMP衰竭而阻止DNA的合成，最终诱导肿瘤细胞凋亡。

Objective Comparison of the efficacy of acyclovir combined with recombinant human interleukin-2(IL-2)and single acyclovir in treating palindromic genital perpes.

目的 比较阿昔洛韦联合重组人白介素-2（IL-2）与单用阿昔洛韦治疗复发性生殖器疱疹的疗效。

Objective Comparison of the efficacy of acyclovir combined with recombinant human interleukin-2(IL-2)and single acyclovir in treating palindromic genital perpes.

目的 比较阿昔洛韦联合重组人白介素-2（IL-2）与单用阿昔洛韦治疗复发性生殖器疱疹的疗效方法随机将84例患者分 2组，观察各组3 月、6个月、12个月后的复发率。

Deparment of Dermatology,The People's Hospital of Dongying,Dongying 257091,China Objective Comparison of the efficacy of acyclovir combined with recombinant human interleukin-2(IL-2)and single acyclovir in treating palindromic genital perpes.

目的 比较阿昔洛韦联合重组人白介素-2（IL-2）与单用阿昔洛韦治疗复发性生殖器疱疹的疗效。

Acyclovir wascontinued for five days, by which time palmar, plantar, and oral lesions were virtually gone.

用药持续5天后手掌、足底和口腔疱疹最终消退。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。