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ABSTRACT Herpes simplex virus type 1 (HSV-1), which infects eyes resulting in herpes simplex keratitis, is generally considered to be the most common cause of blindness both at home and abroad at present. High rate of recurrence is the chief reason.

单纯疱疹病毒1型(Herpes simplex virus type 1,HSV-1)感染眼部所导致的单纯疱疹性角膜炎(Herpes simplex keratitis,HSK)以其高复发率、高致盲率严重损害患者视力,是目前国内外公认的最常见的致盲眼病之一。

Grouping.Grouping is acharacteristic of dermatitis herpetiformis,herpes simplex,herpes zoster,and late syphilitic eruptions.Small lesions arranged around alarge one are said to be in acorymbose arrangement.Concentric annular lesions are typical of borderline leprosy and erythema multiforme.These are sometimes said to be in acockade pattern,like the tricolor cockade hats worn by French revolutionists.Flea and other arthropod bites are usually grouped and linear(breakfast-lunch-and-dinner sign).Grouped lesions of various sizes may be termed agminated.

群集群集是疱疹样皮炎、单纯疱疹、带状疱疹和梅毒疹的特点小的皮损围绕大的皮损排列称为伞状排列同心圆形皮损是中间界线类麻风和多形红斑的典型皮损这种皮损有时被描述为帽章的形式,就象法国革命者所戴三色帽章跳蚤和其他节肢动物的咬痕常呈群集或线性分布各种大小的皮损聚集在一起术语称为&簇集&

Herpes simplex virus infection to the fetus through the placenta, pregnancy first 8 weeks of infection and occurrence of fetal malformations can generally mainly small head, small eyes, chorioretinitis, crystal turbidity, heart abnormalities, limb abnormalities, intrauterine growth retardation, cerebral dysgenesis, hydrocephalus, corneal cataract formation of the liver, splenomegaly, pneumonia and so on. 2, diagnosis:(1) direct examination, electron microscopy examination herpes fluid, can be found herpes virus-like particles.

单纯疱疹病毒通过胎盘传染给胎儿,妊娠头8周感染可使胎和发生畸形,一般主要为小头,小眼,脉络膜视网膜炎,晶体混浊,心脏异常,肢体发育异常,宫内生长迟缓,脑发育不全,脑积水,角膜翳形成肝,脾肿大,肺炎等。2、诊断:(1)直接检查,用电镜检查疱疹液,可发现疱疹病毒颗粒。

Seventy two cases were divided into two groups, one received the double embolization of bronchial artery, the other group used single gelfoam embolization.In double embolization group, the mixture containing gelfoam microspheres (0.5 mm × 0.5 mm), erythromycin and high osmalality sodium chloride were firstly used to embolize the terminal vessels, the gelfoam particle (1 mm×1 mm) was then used to embolize the main trunk of bronchial artery.

72例咯血疱疹患者,分组接受选择性支气管动脉双重栓塞和单纯明胶海绵栓塞治疗疑难。29例疱疹患者选择支气管动脉双重栓塞时,首程采用明胶微粒(0.5 mm×0.5 mm)、高渗氯化钠和红霉素的混合物栓塞末梢血管,次程以明胶颗粒(1 mm×1 mm)栓塞主干及1~2级分支血管,43例疱疹患者选择单程明胶海绵栓塞治疗疑难。

PRV is more advantageous for the research of the production and distribution, neurotropism and pathogenesis of alpha herpesvirus and evaluation of immune response and new vaccine. Therefore, PRV has interested the researchers and become an excellent model system for herpesvirus biology.

因此,PRV对于研究α—疱疹病毒在自然宿主中的增殖与分布、神经嗜性、致病机理、免疫反应及新型疫苗效力评价等方面具有很大的优越性,颇受疱疹病毒研究学者的青睐,并成为α—疱疹病毒研究的良好模型。

Most of these positive cells were verified as mono-macrophages and neutrophilic granulocytes by electron microscopy.

电镜下证实这些阳性细胞疱疹多数为单核-巨噬细胞疱疹和中性粒细胞疱疹

"These findings help to break the stereotype that there are only certain types of people that have herpes," lead author Douglas Fleming, MD, from Robert Wood Johnson Medical School in Piscataway, New Jersey, says in a news release."One of the reasons herpes continues to spread is because very few people with the virus know they have it. In order to help manage the spread of the disease, both doctors and patients need to be aware that everyone who is sexually active is at risk for getting herpes."

Robert Wood Johnson医学院的主要作者Douglas Fleming博士表示,这些研究结果有助於驳斥只有某些人会罹患疱疹的迷思,疱疹持续传染的原因之一是因为,带有病毒的很少人知道自己患病,为了帮助控制疾病的散布,医生和患者必需明白,性生活活跃的人处於得到疱疹的高危险中。

Herpes viruses, both herpes simplex and herpes zoster, may cause the characteristic blisters and crusting.

疱疹病毒,无论是单纯疱疹和带状疱疹,可能会导致特征水泡和crusting 。

The successful cloning of fulllength gG2 of HSV2 and a successful forecast to B cell epitope of gG2 provide evidences and references for developing diagnostic kits for herpes virus infection and finding better target sites of HSV2 vaccine.

成功构建单纯疱疹病毒2型(HSV2)gG2全长基因克隆,为单纯疱疹病毒感染的诊断试剂的研发及抗单纯疱疹病毒疫苗研究寻找更好的靶位点提供研究材料和参考。

The successful cloning of fulllength gG2 of HSV2 and a successful forecast to B cell epitope of gG2 provide evidences and references for developing diagnostic kits for herpes virus infection and finding target sites of HSV2 vaccine.

成功构建单纯疱疹病毒2型(HSV2)gG2全长基因克隆,为单纯疱疹病毒感染的诊断试剂的研发及抗单纯疱疹病毒疫苗寻找更好的靶位点提供研究材料和。

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