疫苗的

Therefore, the progress of HIV infection, purulent infection increase, and the influenza A virus vaccine and the hepatitis B vaccine to reduce the antibody response.

因此，在HIV感染进展时，化脓性感染增加，而对流感A病毒疫苗和乙肝疫苗的抗体反应降低。

Revaccination of patients who were vaccinated with the affected lots is not necessary.

已接种上述批次疫苗的患者没有必要再次接种疫苗。

The Sabin oral antipolio vaccine and the BCG vaccine against tuberculosis are examples of this type of vaccine.

萨宾口服脊髓灰质炎减毒疫苗以及抗结核卡介苗便是这类疫苗的例子。

Carol Pandak says testes tests found the new vaccine to be 30% more effective than the trivalent vaccine.

卡罗尔·潘达克表示测试结果显示新疫苗比三价疫苗的效果要好30%。

Subsequently, the company's September 5 announcement that the company owned subsidiary of Westland Bio Co., Ltd. received a four million vaccines influenza A H1N1 influenza virus vaccine production plan cracker.

随后，公司在9月5日发布公告称，公司控股子公司华兰生物疫苗有限公司接到400万剂甲型H1N1流感病毒裂解疫苗的生产计划。

Westland biological (002,007 shares of it, market, information, the main trading) on the 5th announcement that the company owned subsidiary of Westland Bio Co., Ltd. received the vaccine 4 million Influenza H1N1 influenza virus vaccine production plan cracker.

华兰生物（002007 股吧，行情，资讯，主力买卖）5日公告称，公司控股子公司华兰生物疫苗有限公司接到了400万剂甲型H1N1流感病毒裂解疫苗的生产计划。

DCs acquired by our reformed methods express both CD83 and CD 14 molecules highly, and have a higher density than other domestic reports. The higher TNF in DCs culture medium of HC patient suggests DCs in patient still have antigen presenting ability and by optimization the culture medium would improve its presenting ability and have a potential value in design and application individual vaccine. Although antigens pulsed DCs have a decrescent antigen presenting ability but BCG HSP70 could induce its mature and improve its presenting ability. Suggests BCG HSP70 would be a useful mature inducer. Lymphocytes primed by DCs based HC vaccine have the specific cytotoxicity against HCC lines. The CTL after freezing and anabiotic could prophylaxis and therapy HC xenograft on nude mouse. The results also suggests that CD4〓 lymphocytes play a important role in HC with a good differentiation and would be useful in treatment this kind of HC. After being activated by Peptide LLNQHACAV of hAFP and apoptotic HCCs pulsed DCs respectively, the culture medium of activated lymphocytes both contains a high level Th1 cytokines IL-12 and TNF. Primed lymphocytes appeared a characteristic of NK cells. DCs not only inhibited the growth of human HCC and other cancer cells in vitro but also prevented the growth of HC xenograft on nude mouse in vivo. There are at least three kinds of mechanism playing important role in DC based vaccine ,there are inhibition of DCs, HC specific CTL and cytokines pathway.

诱导出的DC共同表达CD83和CD14分子，CD83分子表达明显高于国内报道；肝癌患者DC培养上清中TNF水平高于健康人，提示肝癌患者DC仍具一定的抗原呈递能力，适当调控可使其行使APC功能，以期在肝癌个体化疫苗中发挥作用；DC负载肝癌可溶性抗原后，抗原呈递能力降低，BCG HSP70可促进DC成熟，增加其抗原呈递能力，预示BCG HSP70有可能成为促进DC活化和成熟的另一重要分子；肝癌DC疫苗在体外诱导肝癌特异性淋巴细胞，活化的淋巴细胞在体外对肝癌细胞的杀伤以特异性CTL为主，同时分泌较高水平Th1型细胞因子IL-12和TNF，并抑制4种肝癌细胞生长；冷冻复苏后的肝癌特异性淋巴细胞可以预防和抑制人肝癌裸鼠皮下移植瘤，提示DC负载肝癌可溶性抗原后诱发的MHC-Ⅱ类限制性CD4〓T细胞有可能在分化程度高的肝癌治疗中发挥作用；用DC和HLA-A2〓DC分别负载凋亡肝癌细胞和hAFP218-226位LLNQHACAV HLA-A2限制性九肽，在体外诱导肝癌特异性淋巴细胞，活化后的CTL细胞分泌较高水平的Th1型细胞因子IL-12和TNF，并具较强杀伤活性，此CTL同时具备NK细胞特征；DC对肿瘤细胞的抑制作用可能是通过吞噬实现的，Fas-L在DC抑制中也起一定作用；DC对人肝癌裸鼠皮下移植瘤的抑制率为97％；在肝癌DC疫苗的作用中，至少联合3种以上机制，即通过DC的直接作用、肝癌特异性CTL和细胞因子途径直接或间接地杀伤和抑制肝癌细胞。

Pavia, from the University of Utah, Salt Lake City, notes that of all the strategies to improve vaccination rates, the policy of mandatory vaccination has generated the most controversy.

Pavia医师在编辑评论中表示，所有策略都是为了改善疫苗接种率，强制施打疫苗的政策素有争议。

The chitosan-based microsphere delivery system enhanced the humoral immune response induced by polytope DNA vaccine.

壳聚糖微球疫苗投递系统可提高多表位DNA疫苗的免疫应答效果。

The findings showed that mothers' knowledge about the primary course of DPT was low (33% correct). The primary source of knowledge was from healthcare providers. Mothers' educational level was statistically associated with know ledge of the DPT vaccine.

研究结果显示：生育第一胎母亲之第一剂三合一疫苗的知识偏低（答对率33.1%）；主要知识来源为医院的医护人员；母亲的教育程度与疫苗之知识的了解呈显著相关，即较高的教育程度有较高的疫苗知识。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。