疫苗的

The findings are very important for overcoming nonresponsiveness and maximizing the impact of vaccine in prevention and control of hepatitis B not only in theory but in practice, and helpful for optimization of hepatitis B vaccination, especially in areas with high endemicity of HBV infection just as China.

研究结果对解决乙肝疫苗无应答问题、充分发挥现有疫苗的预防效果具有十分重要的理论指导和实际应用价值；对进一步优化与完善我国乙肝疫苗接种计划有重要意义。

The executive director, Mitchell Warren, said:"There is little doubt that this finding will energise and redirect the Aids vaccine field."

美国艾滋病疫苗倡导联盟的执行理事米切尔·沃伦说："毫无疑问，这一试验结果将在艾滋病疫苗领域中发挥激励的作用，并重新定位艾滋病疫苗的研发方向。"

Today, the appearance of the "third-generation vaccine"—nucleic acid vaccinepresents a good perspective for controlling leishmaniasis.

近年来，被称为第三代疫苗的核酸疫苗的出现，为内脏利什曼病疫苗的研究提供了一个新的发展方向。

Experimental animals exhibited specific antibodies that were detectable 15 days after the first injection and increased steadily, the IgG2a-specific antibody titers of DNA groups were higher than IgG1-specific antibody titers, and the recombinant protein groups were contrary. The DNA vaccines elicited a T-cell-proliferative responses as well as IFN-γ production upon restimulation with the specific antigens using ELISPOT assay; the ratio of CD4+/CD8+ were lower than that of the control mice.

本研究成功构建了布鲁氏菌基因工程疫苗，在国内尚属首次，利用流式细胞仪的分型技术和ELISPOT法评价布鲁氏菌疫苗的细胞免疫指标将促进我国兽用疫苗及相关产品的实验室质控标准方法的建立和发展，为他们的临床应用奠定基础。

Meanwhile, positive human sera of HCV challenged vaccina ted monkeys after 6 weeks immunized, ALT value rose transiently in monkeys vacci nated by PCX. It was positive in monitoring RNA of HCV using RT-PCR in monkey s era. The result demonstrated that Rhesus monkey immunized by multi-epitope PCX could elicit high-level immune responses.

近年来，由于多表位抗原概念的兴起，在针对EB，HIV等病毒感染的疫苗研究中引入了多表位抗原疫苗［门，这种思路使对HCV疫苗的研究有了新的切入点，F.r.i［'］等用 HCV.H77株 E蛋白的多个表位所制备的兔血清与HCV

System of management of 1.2 convenient and vaccinal children records the data of every vaccinal children well and truly, and the special information data such as disease of allergy history, will vaccinal vaccinal contraindication can make marked clew, for outpatient service vaccinate vaccinal filtration provides a basis.

系统应用后，只要一扫条形码，儿童当日实种疫苗、批号、接种时间就可自动录入，同时可生成预约通知单，一个儿童全程登记不到一分钟时间，节省了大量的门诊登记时间，避免了以往因手工之误而导致的错种、漏种、重种现象发生，提高了工作质量和工作效率。1.2方便接种儿童管理系统能全面、准确地记录每个接种儿童的资料，并将过敏史、疫苗接种禁忌症等非凡信息资料能做出醒目的提示，为门诊预防接种疫苗的筛选提供依据。

A prominence advantage of DNA vaccine as a new generation of vaccine is that it can induce abroad cell immuno-reaction and form long perdured immunity memory, especially the immune regulative DNA vaccine which was constructed by special antigen together with some cytokine genes has more effect and prospect in the anti- coccocidiosis practice.

作为第三代疫苗的DNA疫苗的一个显著优势是刺激机体产生广泛的细胞免疫反应和持久的免疫记忆，尤其应用特定的球虫保护性抗原联合一些细胞因子，构建调节型DNA疫苗，在球虫病防治中具有诱人的应用前景。

"Vaccine production in the U.S. has decreased, which may further erode immunity in the population," the authors write."Once this supply problem is corrected, the ACIP recommendations should be reinstituted."

作者写道：「美国疫苗的生产产量已经降低了，这更加导致了人群免疫力的降低，一旦疫苗供应的问题得到解决，ACIP推荐的『每十年一次的疫苗强化』计划应当重新开始执行。

This is wrong, the state provided the vaccine only a few, such as the influenza vaccine is not in his provisions, but the benefits of influenza vaccine we all know, so as long as it is to the regular injection of epidemic prevention station or hospital, and doctors say they can fight , I would like to have no problem.

这话不对，国家规定的疫苗只有那么几种，比如流感疫苗就不在他规定内，但是流感疫苗的好处大家都知道，所以只要是去正规的防疫站或医院注射，并且是医生说可以打的，我想都没有什么问题。

In particular, the technology of the use of transgenic plants to produce human or animal therapeutic vaccines receives increasing atten-tion. Expressing vaccine candidates in vegetables and fruits open up a new avenue for producing oral/edible vaccines. Transgenic plant vaccine disquisitions exhibit a tempting latent exploiting foreground.

尤其是利用转基因植物技术生产植物疫苗的研究受到了广泛的关注，在转基因植物的可食用部位表达抗原生产人或动物治疗用重组蛋白和疫苗的技术为可食性疫苗的研制开辟了新途径，展现了诱人的开发前景。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。