疫苗原

Materials and 64 dust acarid allergic rhinitis outpatients were randomly divided into 2 groups, 31 patients in the control group were treated with general immunotherapy, 33 patients in the trial group were treated with NHD, the serum level of IL-4, IL-5 was detected by ELISA.

常年性变应性鼻炎患者64例，随机分为常规免疫治疗组31例，标准化尘满变应原疫苗治疗组33例，比较两组患者在接受免疫治疗后的疗效及血清IL-4、IL-5水平。

NHD specific immunotherapy could attenuate the production of cytokine IL-4, IL-5 and is effective for treatment in dust acarid allergic rhinitis.

尘螨标准化变应原疫苗免疫治疗是一种有效、安全的治疗常年性变应性鼻炎的方法，可能通过减少机体IL-4、IL-5的生成，从而减轻IL-4、IL-5对常年性变应性鼻炎患者的免疫毒害作用，发挥其调节免疫的作用，进而达到有效治疗常年性变应性鼻炎的作用。

The key of immunological contraception is to discover a sperm antigen, which is tissue-specific and has the intense antigenicity.

应用疫苗进行避孕的一个最关键的问题是能发现一个精子特异的，且具有强免疫原性的抗原。

Objective To evaluate the immunity of ag85b-recombinant BCG vaccine.

目的研究ag85b-卡介苗重组疫苗的免疫原性。

These results indicate that the trial vaccine has excellent safety and immunogenicity and may be suited for wide use.

试验疫苗的免疫效果达到欧盟标准，其安全性和免疫原性良好，适于推广使用。

And therecombinant protein also reacted with rabbit antiserum against FKC of V.parahaemolyticus and large yellow croaker convalescent sera.

研究结果显示了OmpW具有良好的免疫原性，可能应用于种的快速鉴定和疫苗开发。

Objective To investigate protection of immunization with recombinant BCG-Em Ⅱ/3 vaccine of Echinococcus multilocularis and against challenge with Em protoscolexes.

目的探讨多房棘球绦虫重组卡介苗（BCG-EmⅡ／3）疫苗免疫对Em原头节攻击感染的保护性作用。

The homology of the nucleotide sequences and genetic variation analysis of NDV strains suggested that mere were obvious divergence in gene lever among NDV vaccine strains and epizootic strains isolated from different areas and different ages.The divergence may have effect on amino acid and structure and function of protein in some extent and lead to difference of immunogenicity ,which was one of reason being difficult in preventing from ND.

通过对NDV F基因核苷酸序列同源性比较及遗传变异分析发现：我国不同年代、不同地区分离的NDV毒株与疫苗毒株之间在基因水平上存在较大差异，这种差异对氨基酸及蛋白质的结构和功能可能会有一定影响，而NDVF蛋白的差异同时也造成免疫原性的差异，这很可能是新城疫的免疫防治十分困难的原因之一。

In this study, a recombinant plasmid generating short hairpin RNA was constructed — To construct the recombinant plasmid carrying shRNA to HPV6bL1 and analyze the nucleicacid sequence for further searching new gene therapy method of cauliflower excrescence.

目前对于尖锐湿疣仍无有效的病毒特异性防治措施来保护人类免受其危害，而基因疫苗则为预防HPV感染提供了可能性；L1是HPV6型主要的衣壳蛋白，具有较强的免疫原性，可刺激机体产生保护性的中和抗体。

Objective To observe the immunogenicity of combined hepatitis A and B vaccine.

目的 观察甲乙型肝炎联合疫苗的免疫原性。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。