疫苗

"A particularly interesting finding of this study is that the vaccine achieved fairly good control of blood pressure in the early morning hours," said Juerg Nussberger, M.D., Division of Angiology and Hypertension, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland, who presented the study in a Tuesday media briefing.

Juerg Nussberger博士认为与降压药物相比，高血压疫苗具有以下优势：（1）降压药物半衰期短，无法稳定控制清晨血压，而这正是高血压疫苗所擅长的；（2）高血压疫苗只需每四周注射一次，依从性明显好于降压药物；（3）高血压疫苗可有效控制血压，而降压药物只能使四分之一的患者血压得到成功控制。

Biological Qualcomm reported that since the world recognized the success of the most promising AIDS vaccine trial has been declared a failure, the date of successful AIDS vaccine seems to have become the foreseeable future, the Nobel Medicine Prize, the world's leading AIDS expert David Baldi Professor Moreton speech, claiming that the complexity of HIV based on the variability in the 25 years of human AIDS vaccine can not be found,"and most likely never find such a vaccine."

生物通报道，自从被世界公认最有希望获得成功的艾滋病疫苗试验宣布失败以来，艾滋病疫苗成功之日似乎变得遥遥无期，诺贝尔医学奖得主、世界著名艾滋病研究专家大卫·巴尔迪摩教授发表演说，声称基于艾滋病病毒复杂的变异性，人类在25 年内不可能找到艾滋病疫苗，"并且很有可能永远也找不到这种疫苗。"

"There are 32 million potential recipients in the United States alone. Merck stands to make $11.5 billion from this one immunization," Dr. Lex said. However, there are some political hurdles to overcome."It is opposed by religious leaders" on the grounds that vaccinating their young daughters would give them the green light to engage in sexual activity, he said — an argument he disagrees with.

Lex医师表示，单在美国就有3，200万潜在的疫苗接受者，制造该疫苗的默克药厂预估可以获利115亿美金，不过，还有一些政治上的困难有待克服，此疫苗受到宗教领袖反对，他们认为对年轻女孩注射该疫苗会让她们认为可以安全进行性行为，但Lex医师对此不表同意。

CSFspread severely in our country and about 39.65% of pigs died of disease died of CSF. The economic lossesreach a hundred million RMB. The Hog cholera lapinized vires vaccine was developed in 1956 in ourcountry and was accepted the most safe CSF vaccine using all over the world. Many countries haveeliminated the CSF by this vaccine.

我国是猪瘟流行较严重的国家，每年因猪瘟死亡的猪约占病死猪的39.65％，经济损失达100亿元左右。1956年我国成功的研制出猪瘟兔化弱毒株疫苗，此疫苗被认为是最安全的疫苗而被全世界广泛的采用，许多国家应用此疫苗消灭了猪瘟。

The two valence vaccine consisting of catalase, adhesion conservation and adjuvant has better immunotherapeutic effects than the single valence vaccine. More H. pylori vaccine research should be directed to the multivalence vaccine.权威期刊K-Rf l4tw

由过氧化氢酶和黏附素保守区加免疫佐剂组成的二价口服疫苗较单价口服疫苗有更好的免疫治疗效果，多价疫苗是未来H.pylori疫苗的研制方向。

There was significant difference in fever rate between experiment group with Shanghai MMR vaccine and control groups with mump vaccine and rubella vaccine.

与对照疫苗比较，仅沪MMR疫苗发热率高于腮腺炎疫苗及风疹疫苗，差异有统计学意义，其他各反应差异均无统计学意义。

Healthy rabbits were inoculated each with vaccines of the recombinant Pilin and the recombinant fused Pilinn-IL2 protein at 250ug per dose to potentiate the immunogenicity. The D. nodosus Pilin vaccine and the killed D. nodosus whole cell vaccine were also inoculated into rabbits as controls in order to compare with the above two recombinant vaccines.

用纤毛蛋白基因工程疫苗、Pilin-IL-2融合基因工程疫苗分别免疫健康家兔，初步进行了纤毛蛋白疫苗和Pilin-IL-2融合基因工程疫苗的免疫原性试验，并同时用节瘤拟杆菌菌体灭活疫苗及菌体纤毛蛋白疫苗免疫家兔，进行了免疫原性比较试验。

This review covered the following aspects in the development and application of CSF DNA vaccines: construction and evaluation, application of adjuvants, combination with other vaccines and the existing problems and solutions.

以下从猪瘟DNA疫苗的构建和评价、佐剂在猪瘟DNA疫苗中的应用、猪瘟DNA疫苗与其他疫苗的联合应用以及目前猪瘟DNA疫苗存在的问题和解决途径等方面做了比较全面的阐述。

Given the duration of immunity is 10 years, introducing a HPV vaccination program in 12-year-old girls in Taiwan compared to current screening practice remained fairly cost-effectiveness (ICER of NT$1,152,727/QALY).

在假设疫苗仅具备十年保护期的情况下，台湾地区引进12岁健康女性人类乳突病毒疫苗接种计画，相较於不接种疫苗，仍符合成本效果(ICER值为NT$1，152，727/QALY低於世界卫生所建议ICER之标准阈值=3倍的GDP NT$1，510，875/QALY)；且若疫苗具备终身保护期，则人类乳突病毒疫苗接种方案将非常符合成本效果(ICER值为NT$201，346/QALY低於NT$503，625/QALY)。

Given the duration of immunity is 10 years, introducing a HPV vaccination program in 12-year-old girls in Taiwan compared to current screening practice remained fairly cost-effectiveness (ICER of NT$1,152,727/QALY).And if vaccine could provide lifetime immunity, vaccination program would be very cost-effectiveness (ICER of NT$201,346/QALY).

在假设疫苗仅具备十年保护期的情况下，台湾地区引进12岁健康女性人类乳突病毒疫苗接种计画，相较於不接种疫苗，仍符合成本效果(ICER值为NT$1，152，727/QALY低於世界卫生所建议ICER之标准阈值=3倍的GDP NT$1，510，875/QALY)；且若疫苗具备终身保护期，则人类乳突病毒疫苗接种方案将非常符合成本效果(ICER值为NT$201，346/QALY低於NT$503，625/QALY)。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。