疫苗

MVA85A is the first new vaccine to be evaluated in Mycobacterium tuberculosis latently infected subjects.

目前亟需一个新的TB疫苗，MVA85A是第一个在结核分枝杆菌潜伏感染受试者身上评估的新疫苗。

These results show that the artificial synthetic antigen SW-BSA vaccine has a protective effect to rabbits and goats. It can delay the locoweed poisoning time of animals 30 d 40 d and provide a basis for the SW-BSA vaccine clinical trial.

以上结果表明，SW-BSA人工合成抗原疫苗对家兔和山羊具有一定的保护作用，能够延缓疯草中毒时间30 d～40 d，为SW-BSA疫苗的临床应用提供了试验依据。

It is different from current developed anti-cancer vaccine through Merck, which would not be used in cancer patients.

这与Merck公司新近研发的抗肿瘤疫苗是不同的，因为那种抗肿瘤疫苗不能用于肿瘤患者。

Merck's vaccine is one of many in or heading into clinical trials, and different types of vaccines are known to stimulate different kinds of immunity.

Merck的疫苗是进行临床实验的一种，而不同类型的疫苗可以引起不同的免疫反应。

Antigenic protein vaccines contain many CD8~+ T cells epitope and CD4~+T cells epitope, they can be presented by not only MHO I molecule but also MHC-II molecule and active immune response.

蛋白疫苗的特点是含有己知和未知的CD8~+T细胞表位和CD4~+T细胞表位，不被特定的HLA表型所限制，既可通过MHC-Ⅰ类分子途径，又可通过MHC-Ⅱ类分子途径激活抗肿瘤免疫应答，因此采用蛋白疫苗可能具有更大的临床应用意义。

Combined hepatitisA-measles-varicella vaccine is better than monovalent vaccine in improving the cellular immune function .

甲肝-麻疹-水痘联合疫苗增强机体细胞免疫功能的作用强于单价疫苗。

The team, led by Eric Kremer of the University of Montpellier in France, examined why people participating in the STEP vaccine trial who had previously been exposed to a cold virus, adenovirus 5, seemed more likely to become infected with HIV-1 than those who hadn't been exposed to the virus (see ' HIV vaccine may raise risk ').

法国的蒙特利尔大学里的EK和他的带领的团队做了这样的一个"分步疫苗试验"的研究，试验为什么那些曾经暴露于被冷冻腺病毒5的受试者比那些从未没有接触过这些病毒的人更加容易感染艾滋病病毒。（见文章《人类免疫缺陷病毒疫苗有可能引发灾难》）。

After the initial inoculation of measles vaccine and the effects of multiple cropping well, but with age, measles IgG antibody level decreased gradually, to deal with high-grade primary school (grades 4 to 6), junior high, high school students to carry out measles vaccination and immunization do good response, so the prevention and control of epidemics and outbreaks of measles.

经过麻疹疫苗初次接种与复种后效果良好，但随着年龄的增长，麻疹IgG抗体水平逐渐下降，应对小学高年级（4~6年级）、初中生、高中生进行麻疹疫苗强化免疫以及做好应急工作，从而预防和控制麻疹的流行和暴发。

Methods The HBsAg content and RP of key samples at purification step of production of recombinant HB vaccine were determined by Kehu a Plate EIA, Abbott MUREX Plate EIA and ECI, and the results were compared with that by Abbott Bead EIA, based on which the precisions of the three methods were analyzed.

分别用科华板式EIA法、雅培MUREX板式EIA法、罗式电化学发光法与雅培珠式EIA法对比检测重组乙型肝炎疫苗生产过程中纯化工序关键样品的HBsAg含量和疫苗的RP值，并分析3种方法的精密性。

Part Ⅱ Objective: To study the immunoprotective and the immunotherapic effects of the new nucleic acid vaccine of the hepatitis B: pVAX1-C3d-S2S; respectively in normal and HBV transgenic mice after being inoculated intra- muscularly with this Eukaryotic Expression Plasmid, such as the in situ production of the expressed protein in muscle tissue section and specific humoral immune response in normal mice、the variation of specific antigen、antibody and HBV DNA, especialy the changes of specific antigen in liver.

第二部分新型乙肝核酸疫苗pVAX1 C3d-S〓S免疫预防效应和治疗作用的研究目的：研究含有新型分子佐剂补体C3d的HBV adw血清型的乙肝核酸疫苗重组真核表达质粒pVAX1-C3d-S〓S接种正常BALB／c小鼠和HBV转基因小鼠后，其免疫预防作用（接种局部肌肉中特异性抗原蛋白的表达和所诱生的体液免疫应答规律）以及免疫治疗作用（血清中特异性抗原的表达、特异性抗体的产生、HBV DNA的消长和肝组织中抗原表达的变化）。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。