疟原虫

Conclusions】 It is suggested intramuscular injection is an effective immune route. Mice inoculated with coding different stage gene recombinants alone or mixedly could all induce increased humoral and cellular immune response, and NK cell activity.

提示肌肉注射为一有效的DNA疫苗免疫途径，采用编码恶性疟原虫有性期阶段或无性红细胞阶段的重组质粒单独或两者混合免疫小鼠，均能诱导明显的体液免疫反应、细胞免疫反应和NK细胞杀伤活性。

After injecting recombinant pcDNA3-EBA175/HRPⅡ or pcDNA3-Pfs25 alone or mixedly into mice by intramuscular route, all of them showed that sera IgG value increased, splenic T lymphocyte proliferation stimulated by specific antigen of Plasmodium falciparum increased, the ratio of CD4+/CD8+ decreased and NK cell activity increased.

pcDNA3-EBA175/HRPⅡ与pcDNA3-Pfs25分别单独肌肉注射或两者混合肌肉注射免疫小鼠后，均可见血清IgG抗体滴度增高，针对恶性疟原虫抗原的特异性T淋巴细胞增殖反应增强，CD4+/CD8+ T细胞比率下降以及NK细胞杀伤活性增强。

The recombinant pcDNA3-EBA175/HRPⅡ and pcDNA3-Pfs25 were injected alone or mixedly into mice by intramuscular way respectively. The kinetic changes of IgG antibody value, the splenic lymphocyte proliferation, the ratio of CD4+/CD8+ subgroups and NK cell killing activity in each group were observed.

将恶性疟原虫FCC-1/HN株重组质粒pc DNA3-Pfs25及pcDNA3-EBA175/HRPⅡ经骨骼肌途径分别单独注射或两者混合注射免疫BALB/c小鼠，观察免疫后不同时间点血清中IgG抗体滴度、脾淋巴细胞增殖反应、CD4+/CD8+ T细胞亚群比值和NK细胞杀伤活性的变化。

Furthermore, the anti-chloroquine plasmodia strain have cross - anti character in clinical. Artemisinin from Artemisia annua L.

目前，在临床上疟原虫对治疗疟疾的药物有较强的耐药性，并表现出明显的交叉耐药性。

Targeting these sticky proteins with drugs is difficult, however, as plasmodia contain many different varieties, which they use to evade the human immune system.

但是，以这些粘性蛋白质作为药物靶标非常困难，这是由于疟原虫用于侵入人类免疫系统的蛋白质种类很多。

After plasmodia infect a blood cell, they send out clusters of sticky proteins to the cell surface, enabling them to attach to blood vessels and escape destruction by the host's spleen while they replicate.

疟原虫感染血细胞后，它们会向细胞表面释放出一系列粘性蛋白质，使其能够附着在血管上，以便逃避它们复制时宿主脾脏对它们的破坏。

At present, it is only sensitive to Pycnonotus jocosus.

在实验调查中该疟原虫仅寄生于红耳鹎。

Plasmodium guangdongensis parasites at Pycnonotus jocosu, classify into subgenus Novyella, natural infected rate is 10%.

广东疟原虫：属诺维亚属，寄生于红耳鹎，自然感染率是10％。

Objective To understand the effects of different doses of Artesunate on sporogonic stages of Plasmodium cynomolgi in Anopheles dirus.

目的了解不同剂量青蒿琥酯对食蟹猴疟原虫孢子增殖的影响。

Plasmodium heteronucleare parasites in Bambusicola thoracica, is placed in subgenus Novyella, natural infected rate is 30%.

异核疟原虫：属诺维亚属，寄生于灰胸竹鸡，自然感染率为30％。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。