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To analyze 12 cases (male 10 and female 2) of double infected with typhoid fever and malaria over the past ten years in our hospital. Results: Of them, 8 cases suffered fioom typhoid fever with tertian malaria, 3 cases of typhoid fever with falciparum nalaria, anid the other one was diagnosed by anti-malaria treatment.

收集我院近十年来的伤寒、疟疾重叠感染患者12例(其中男10例,女2例)结果:12例伤寒重叠感染间日疟8例、恶性疟3例,疟原虫阴性的1例是在确诊伤寒后,按伤寒治疗,高热持续不退,贫血加重,经诊断性抗疟治疗,体温降至正常才诊断为重叠感染的。

To identify the location of Pfdyn, Triton X-100 and Biotin were used to extract different cell components'proteins.

在培养三周后出现了可以抗WR99210的含稳定pHD22y-Pfdyn微粒体的恶性疟原虫的克隆。

During asexual stages in the blood, it occur in the mature erythrocyte, and it's ring-body localizes at the subpole of the host red cell, and the trophozoite at one pole.

疟原虫红内期寄生于成熟红细胞内,环状体一般位于寄主细胞的亚极,而滋养体则多数分布于寄主细胞的一极。

Malignant plasmodium was founded in their blood samples.The epidemiological study showed,they had never gone to the higher malaria-epidemic areas in our country,such as Yunnan,Hainan,Guangxi,etc.During living overseas,they were all bitten by mosquito.Three cases were first infected,and others were recrudescence sufferers.When they came to hospital,the temperature was higher than 38.5℃.Except for the clinic symptom such as chill,fever,sweat etc.,five cases emerged tumid spleen and anaemia symptom.

结果〕温州口岸2005年1~7月共发现8例疟疾患者,均为国内人员国外感染,其中男性7例,女性1例,血液涂片均查到恶性疟原虫;流行病学个案调查结果显示,8例患者在国外期间均有蚊虫叮咬史;3例为初发病例,5例为复发病例;8例患者就诊时体温均超过38℃,并出现畏寒、发热、大汗等典型的疟疾临床症状,5例患者出现脾肿大和贫血症状,患者均无并发症状出现。

Ongoing projects involve targeted gene disruption, high-throughput approaches for functional exploitation of Plasmodium and Anopheline genomes and identification of molecular components of the recombination machinery in malaria parasites.

正在进行的项目包括有针对性的基因破坏,高通量的方法开发功能疟原虫和按蚊基因组和分子识别元件的重组机制的疟疾寄生虫。

The prophylactic trials made in 2 chlor...

实验室研究表明本药对疟原虫的组织期、红内期、孢子增殖期均有作用,据此提出了复方硝喹的合理使用建议。

Objective To test the in vitro effect of daphnetin on cytochrome C oxidase and ribonucleotide reductase activity of Plasmodium falciparum . Methods P.

摘要目的体外测定瑞香素对恶性疟原虫细胞色素C氧化酶及核糖核酸还原酶活性的影响。

Daphnetin significantly reduces the COX and RNR activities of Plasmodium falciparum in vitro .

在体外瑞香素可显著降低恶性疟原虫的细胞色素C氧化酶及核糖核酸还原酶活性。

The inhibition level of the COX activity by daphnetin after being treated for 2, 4, 8 and 12 h were 0.6%, 73% and 80% respectively and the inhibition level by daphnetin at different concentrations (0.1, 1, 100 and lmmol/L) for 6h was 3%, 31%, 53% and 84%, respectively.

在体外瑞香素可显著降低恶性疟原虫的细胞色素C氧化酶及核糖核酸还原酶活性。

The effect of daphnetin and daphnetin-Fe complex on COX and RNR activity of P.falciparum was tested by ultraviolet spectrophotometer and electron spin resonance respectively.

结果 体外同步培养的恶性疟原虫经瑞香素(100μmol/L)作用2、4、8和12h后,COX活性分别被抑制了0、6%、73%和80%;在瑞香素浓度为0.1、1、100和1000μmol/L,作用6h后,COX活性分别被抑制3%、31%、53%和84%;而瑞香素-Fe复合物对COX的影响几乎消失。

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