疗效

In this paper, we illustrated some statistical issues of confirming efficacy in clinical trials, including its conditions, the determination of clinical margin, the forms of the null and alternative hypothesis and confidence intervals, the choice of endpoints and some miscellaneous considerations.

本文从统计学角度阐明了以安慰剂作为对照和以阳性药物作为对照的3种临床试验确认疗效的条件、确认疗效的界值制定、确认疗效的假设检验方法、确认疗效的可信区间方法、以及确认疗效的指标选择等方面需要注意的问题。

The therapeutic efficacy in posterior extension sitting position occupying 11-20° was better in upper hind neck; the therapeutic efficacy in anteversion sitting position occupying 11-20° was better in inferior neck; the therapeutic efficacy in anteversion sitting position occupying 1-10° was better in neutral position sitting position.

即上颈段椎动脉型颈椎病患者坐位后伸11°~20°牵引疗效较好，下颈段椎动脉型颈椎病患者坐位前屈11°~20°牵引疗效较好，混合型椎动脉型颈椎病患者坐位前屈1°~10°疗效较好。

Used the GA to Jingo three point, we have treated 60 cases CS patient, healed 22 cases, obvious effects 21 cases, effects 13 cases, no effects 4 cases, whole effects rate is 93. 33%, GA group's therapeutic effects is significance better than that of controlled group, we measure CS patient's pain by the Shortform McGill Questionnaire, found that GA has a better effects of analgesia than that of contraction, GA can stop pain in three course. After analysis the relationship between age and clinical therapeutic effects, we found that both of the two therapeutic method have a good effects for the young, but a bad effects for the old.

应用电针颈三针为主，配以辨证取穴，经治60例CS患者，痊愈22例，显效21例，有效13例，无效4例，总有效率93.33％，疗效显著优于牵引对照组；应用简化McGill疼痛询问量表，对CS患者疼痛进行客观量化，发现经三个疗程的治疗，电针组对疼痛的改善明显优于对照组，电针组三个疗程对疼痛均有显著改善，第一疗程对疼痛的改善显著优于对照组；经过对两组病例不同年龄段与疗效的关系分析，发现两种疗法均是对年轻者疗效显著，对年老者疗效较差。

(1)This three schemes mentioned above are effective for weight reduction, among them, the effect is best by using sibutramine and metformin together, which is second-best by using sibutramine simply and tertius by metformin.

①三种治疗方案对减肥均有疗效，其中西布曲明和二甲双胍联合治疗疗效最佳，单用西布曲明疗效次之，而单用二甲双胍疗效最差。

To investigate feasibility and effect of schizophrenia treatment by stereotactic lesioning, CRW stereotactic apparatus and PICKER spiral CT were used to define nucleus location and RADONICS radiofrequency instruments were used to lesion different subnucleuses of amygdala and the front part of callosal gyrus.

采用CRW立体定向仪和PICKER螺旋CT定位，用RADONICS毁损仪毁损杏仁核不同亚核团和扣带回前部治疗精神分裂症 3 5例，并进行了一年的随访。以临床疗效总评量表评定疗效标准为指标，评定病人疗效，旨在探讨立体定向毁损杏仁核不同亚核团和扣带回治疗难治性精神分裂症的可行性和疗效。

Outcomes were considered excellent if the patient had complete symptomatic resolution of epiphora and dacryocystitis and normal tear drainage on examination, good if the patient had only minimal residual symptoms or a minimally delayed dye disappearance test, fair if the patient had moderate residual symptoms or delayed tear drainage, and poor if there was no improvement.

若患者的症状如溢泪和泪囊炎完全改善以及检查发现泪液排泄正常，被认为疗效极佳；若患者仅有轻微的遗留症状或染料排泄轻微延迟被认为疗效好；若患者有中度的遗留症状或染料排泄延迟，被认为疗效尚可；若没有任何改善，被认为疗效差。

RESULTS: It was found that the curative effects on squamous cell carcinoma in the near future were better than those on other pathologic types, on hypovascular lung cancer were superior to those on hypervascular cancer, on carcinomas in larger airways were better than those on carcinomas in smaller airway, and the effects of multiple treatment were better than those of one treatment.

结果： 鳞癌的近期疗效明显优于其他病理类型；乏血管型的近期疗效明显优于富血管型者；大气道肿瘤的近期疗效优于小气道者；多次治疗的近期疗效优于单次治疗者；临床分期的近期疗效与治疗效果无关。

Results: it was found that the curative effects on squamous cell carcinoma in the near future were better than those on other pathologic types, on hypovascular lung cancer were superior to those on hypervascular cancer, on carcinomas in larger airways were better than those on carcinomas in smaller airway, and the effects of multiple treatment were better than those of one treatment. the curative effects in the near future were not associated with the clinical stages.

结果： 鳞癌的近期疗效明显优于其他病理类型；乏血管型的近期疗效明显优于富血管型者；大气道肿瘤的近期疗效优于小气道者；多次治疗的近期疗效优于单次治疗者；临床分期的近期疗效与治疗效果无关。

The model of AR combining Qi deficiency syndromes on rats is successful reconstructed. That Mastocyte released inflammation factors by IgE mediated and a series of phlegmasia occurred subsequently is the major pathologic basis of AR.

体质调整保健药物&敏康片&可以改善变应性鼻炎患者的症状和体征，近期疗效和远期疗效均优于对照药物金施尔康（P.05-P.01），且远期疗效优于近期疗效，对气虚证型患者的疗效优于对照药物金施尔康（P.01）。3。

The effect of treatment is negatively correlated with the course of disease, generally, the effect is much worse with the course of disease is much longer; The effect is positively correlated with the course of treatment, it is better if the course of treatment is longer.The group of more than one year is much excellent than the group of less one year. The ex-electroencephalogram before treatment is normal, on edge and a little abnormal, the effect is better. As regards CT or MR result, there is difference between the effective group and the ineffective group. The result of CT and MR is negative, the effect is better, and the effect to demyelination and leukoencephalopathy is most worst.However,for the tipe of much abnormality, the effect is the most worst.The effect is related to course of disease.The effect is better if the course is shorter.There is no difference in the tipe of disease the symptoms before episode, the frequency of episode, the inducing reasons, the age, sex and so on.

病程的长短与疗效存在负相关关系，病程越长疗效越差；疗程与疗效存在正相关关系，疗程越长疗效越好；疗前脑电图的异常程度与疗效存在负相关关系，正常、边缘及轻度异常者，疗效较好，重度异常者疗效最差；无效组与有效组在CT及MR检查结果上有差异，有阴性者疗效好，阳性者疗效差，脱髓鞘及脑白质病疗效最差的趋势；疗效与性别无相关性；无效组与有效组在发作类型、既往病史、辨证分型、发作先兆、疗前发作频率、诱因、发病年龄、就诊前所用药物方面无差异。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。