疏

On the basis of the initial mechanism of deiodinase and the idea of hapten design derived from the method of"hydrophobic pocket modification", three haptens of thyroxine derivatives, o-methyl-〓, o-benzyl-〓 and o-p-nitro-benzyl-〓 with successively-raising hydrophobicity, were designed and synthesized, and their structures characterized.

以天然脱碘酶的初步催化机制和疏水腔修饰法的半抗原设计思想为依据，设计合成了三种疏水性不同的甲状腺素衍生物半抗原：o-methyl-〓，o-benzyl-〓和o-p-nitro-benzyl-〓，并对其结构进行了表征。

The so-called own steam consumption of steam traps, generally refers to steam leak, the steam trap is the action necessary steam amount and the sum of heat loss.

所谓蒸汽疏水阀自身的蒸汽消耗量，一般是指蒸汽泄漏而言，是蒸汽疏水阀动作需要的蒸汽量和散热损失量之和。

Organics which could be volatilised easily or difficultly decreased fast at the early days, then decreased slow, but the organics which can volatilised easily decreased faster. Hydrophilic organics in the raw water decreased , while hydrophobe organics incresed. 4 Stainless steel and acid-resistant keramics showed less effect on the water's qulity, while the fiber steel which had used for storage in the experiment showed great effect.

随着贮存时间的延长，水中4KD～10KD所占比例升高，而4KD以下的有机物所占比例则下降；水中难吹脱性有机物与水中易吹脱性有机物都减少，且初期下降快后期下降慢，但易吹脱性有机物减少速度快于难吹脱性有机物；水中亲水性有机物所占比例下降，而疏水性有机物所占比例上升，发生了亲水性TOC向疏水性TOC转化。

In order to find screening rules suitable for lead compounds of pesticide,five descriptors:logarithm of partition coefficient of octanol/water,relative molar weight,number of hydrogen-bond donors,number of hydrogen-bond acceptors,polar surface areaand carcinogenic and mutagenic toxicities of 242 fungicides,512 herbicides and 399 insecticides were calculated and analyzed.

1996年，Lipinski通过对2000多种口服药物进行分析，提出了用于药物分子筛选的&5规则&，即化合物疏水常数(CLogP≤5或MLogP≤4.5)，相对分子质量不大于500，氢键给体数不大于5和氢键受体数不大于10[1]。2003年，Andrew等报道了从高通量筛选结果中获取先导化合物的规则：化合物疏水常数≤3，相对分子质量小于450[2]。

Secondly, the experimental research advances of cyclopeptide nanotubes using as the templets to produce biosensors by synthesis with functional nanomaterials such as electronic, optical and magnetic ones.

首先介绍了带合适疏水性侧链的环肽纳米管在模拟生物跨膜离子通道方面的实验和理论研究进展，重点论及环肽纳米管的结构、极性和侧链的疏水性等对离子通道传输行为的影响以及分子动力学模拟研究水通道的进展。

Unique inverted bucket steam traps with drain sumps are adopted to assure sound operation of the steam traps under extremely atrocious conditions.

为了使蒸汽疏水阀在极端恶劣的工况下也能正常工作，采用一种独特的带有集水仓的倒吊桶型疏水阀。

Sythesis and application of chlorostyrene-DVB strongly acidic cation exchange resin ;2. For this study,a series of poly( p -amino styrenes) with various amounts of supported hydrogen chloride,and a series of strongly acidic cation exchange resin s with various exchange capacity were synthesized,and their catalytic property for ketalization of cyclohexanone and glycol were investigated.

通过测定固载了不同量的氯化氢的聚和不同交换量的强酸性阳离子交换树脂催化的环己酮与乙二醇的缩酮化反应缩酮的收率，研究了聚合物固体酸催化剂的疏水性对其催化缩酮化反应性能的影响；发现在一定范围内增加催化剂的疏水性，可提高缩酮化反应的收率。

Very good results were obtained in logP modeling for carboxylic acid, ethanol, phenol, aldehyde, ketone, ether, ester and amine. A QSPR model of logP for many kinds of substances was established by multi-linear regression with the first-order molecular connectivity valent index 〓 and the number of hydrogen bonds N as two patameters.

利用这两类结构参数，分别建立了脂肪族羧酸、芳香族羧酸、醇、酚、醛、酮、醚、酯、胺类物质的疏水性常数定量模型；在此基础上，建立了包含8类基本有机物144种物质的疏水性常数的定量模型，并提出logP的简化模型。

The results of its fluorescence probe showed that when the guanidine hydrochloride concentration in denaturation solution was about 1.0 mol/L,there existed some stable hydrophobic regions,which could interact with a hydrophobic reagent 8-anilino-1-naphthalene sulfonic acid,in the partially folded intermediate of Bacillus amyloliquefaciensα-amylase;with the denaturation concentration increasing,the stable hydrophobic regions disappered.the results of fluorescence quenching using acrylamide and potassium iodide as quenchers showed that using acrylamide as quenchers,with the protein denaturation extent increasing,the number of Trp that can be quenched increased untill all the Trp residues were quenched;Using potassium iodide as quenchers,with the maximum number(8) of tryptophan residues in a partially folded intermediate Bacillus amyloliquefaciensα-amylase molecule could be quenched by potassium iodide;with the denaturation concentration increasing,the number of Trp that can be quenched decreased to 5.the results of their protein electrophoreses and SEC showed that no aggregate or aggregate precipitation of Bacillus amyloliquefaciensα-amylase formed during the whole unfolding/refolding procedure of Bacillus amyloliquefaciensα-amylase induced by guanidine hydrochloride or urea.

ANS外源荧光探针结果表明：盐酸胍诱导的芽孢杆菌α-淀粉酶分子去折叠过程中存在着能够与探针分子1-苯胺基-8-萘磺酸结合的稳定的疏水区域；而随着芽孢杆菌α-淀粉酶分子在盐酸胍溶液中变性程度的加深，这一疏水区域逐步被瓦解。丙烯酰胺和碘化钾猝灭结果表明：在盐酸胍溶液中，随着芽孢杆菌α-淀粉酶分子变性程度的进一步加深，其分子内能够被丙烯酰胺接近的色氨酸残基逐渐增多，直至全部被猝灭。但位于芽孢杆菌α-淀粉酶分子表面的能够被碘化钾猝灭的色氨酸残基，在中间态芽孢杆菌α-淀粉酶分子中数目达到最大的8个，而随着其分子变性程度的进一步加深，反而减少至5个。

Objective : To observe clinical study of Shuxuetong injection (puring material of shuizhi and dilong) on treating Primary nephritic syndrome, to investigate clinical effect of Shuxuetonginjection on treating Primary nephritic syndrome, provide objectiveunder on treating Primary nephritic syndrome.

目的：通过对疏血通注射液治疗PNS的临床观察，探讨疏血通注射液治疗PNS的临床疗效，为临床治疗PNS提供客观依据。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。