畸胎瘤

Methods Two cases of AT/RT were studied by hematoxylin-eosin, reticulin and immunohistochemical staining.

目的 探讨中枢神经系统非典型畸胎样／横纹肌样瘤的临床病理特征、诊断及鉴别诊断。

Results Histologically, AT/RT was characterized by the presence of rhabdoid cells associated with various degrees of primitive neuroectodermal, epithelial or mesenchymal differentiation.

结果 非典型畸胎样／横纹肌样瘤具有特征性的横纹肌样细胞，伴有不同程度的原始神经外胚叶、上皮和间质分化。

RM has special morphological characteristics; it should be differentiated from gemis tocytic astrocytoma, atypical teratoid/rhabdoid tumor, and malignant melanocytoma.

RM有特殊的组织学特点，应注意与胖细胞型星形细胞瘤、非典型畸胎样瘤/横纹肌样瘤、恶性黑色素瘤等鉴别。

For tumors which have been well sampled and exhibit (1) a microcystic pattern and regions with lobulated cellular masses with intervening, sometimes hyalinized fibrous stroma,(2) an absence of morphologic features enabling any other specific diagnosis in the sex cord-stromal category,(3) an absence of epithelial elements, and (4) an absence of teratomatous or other germ cell elements, we propose the designation microcystic stromal tumor.

我们很好地抽样调查了4例肿瘤，显示：（1）微囊样式和有时插入玻璃样变的纤维间质中的分叶状细胞团区，（2）能造成在性索间质这个大类中其他具体诊断的形态特征缺失，（3）上皮成分缺失，（4）畸胎或其他胚芽细胞成分缺失，我们提议定其名为微囊性间质瘤。

There were all kinds of tissue cells in the teratomas acquired from in-vitro differentiation, such as, neuro epithelium, skeletal muscle, respiratory epithelium. This further proved the isolated mouse ES cells could differentiate into three germ layers of tissue types.

体内分化实验所获得的畸胎瘤中存在各种组织细胞，如一些神经上皮样组织；横纹肌；呼吸上皮样组织等，这进一步证明所分离获得的小鼠ES细胞具有三个胚层的分化能力。

After prolonged culture, the cells formed teratomas when injected into seere combined immunodeficient beige mice and expressed markers characteristic of undifferentiated human ES cells.

经过长时间的培养，在注射到合并严重免疫缺陷的beige小鼠体内后，这些细胞仍可形成畸胎瘤并表达未分化的人ES细胞的特征性标记物。

TVS combining with CDE appears more predictive value in hemorrhagic corpora luteum and mature cystic teratomas.

TVS结合CDE对卵巢良性畸胎瘤及黄体血肿有较高的诊断价值。

At the end of 8 weeks, subcutaneous teratoma was detected in two nude mice, including 3 layers of tissues: sebaceous gland, fat, glandular organ, glandular epithelium and squamous epithelium. At day 4, embryoid body was found and cells were positive for actin, nestin and keratin.

接种8周末，2只小鼠均形成皮下畸胎瘤，其内存在囊括3个胚层的组织结构，包括皮脂腺、脂肪、腺体及腺上皮、鳞状上皮等。

The parthenogenetic blastocysts and morulas were seeded on MEF feeder respectively to examine the primary ICM appearance and compare the derivation rate, Results: Twelve batches of mouse parthenogenetic embryonic stem cells were established.

结果：共建立了12株小鼠孤雌胚胎干细胞系，这些细胞SSEA-1抗原阳性，SSEA-4，TRA-1-81，TRA-1-60表面抗原阴性，具有AKP活性，保持正常染色体核型，体内外分化分别形成畸胎瘤和拟胚体。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。