甲醇

Tetrachloroterephthalic acid was prepared by chlorinating terephthalic acid, oleumsolvent and iodine catalyst. Tetrachloroterephthalic acid was acylated by sulphurous oxychloride in the presence of DMF to form tetrachloroterephthaloyl chloride. The acyl chloride product was fluorinated by potassium fluoride and esterified by methanol to synthesize dimethyl tetrafluoroterephthalate. The ester was reduced with potassium borohydride and lithium chloride to give tetrafluoroterephthalyl alcohol. The above product was bromated in the hydrobromic acid to obtain 4-bromomethyl-2,3,5,6-tetrafluoro-benzene methanol. 4-Methyl-2,3,5,-6-tetrafluorobenzene ethanol was obtained by reducing the bromide with magnesium. In the exist of DCC and DMAP, tefluthrin was got by the condensation reaction between 4-methyl-2,3,5,6-tetrafluoro-benzene methanol and-(1RS,3RS)- 3-(2- chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl cycolpropanecar-boxylate acid.

对苯二甲酸与氯气在碘存在下以发烟硫酸为溶剂进行氯化制备四氯对苯二甲酸；再以DMF为催化剂与二氯亚砜反应生成四氯对苯二甲酰氯；以氟化钾为氟化剂，环丁砜为溶剂置换氟化，再与甲醇酯化得到四氟对苯二甲酸甲酯；以KBH4-LiCl为还原剂二甲醚为溶剂反应制得四氟对苯二甲基苄醇；以氯苯为溶剂在溴化氢溶液中溴化得到溴化产物；在乙醇溶液中经镁粉还原得到4-甲基-2，3，5，6-四氟苄醇；甲基苄醇与功夫酸在催化剂二环己基碳二亚胺和4-二甲氨基吡啶作用下缩合得到七氟菊酯，总收率达43.6%。

Investigation of major metabolic pathways of SFZ-47 in animals The metabolites of SFZ-47 in rabbit urine following oral administration were separated and detected with HPLC and LC-MS methods. On the basis of the chromatographic behavior and mass spectra of the metabolites as well as biotransformation pathways of drugs with the partial structure of SFZ-47, the hydroxylic derivative 4-(3H-1, 2- dihydro-1-pyrrolizinone-2-methylamino benzyl alcohol and the carboxylic derivative 4-(3H-1, 2-dihydro-1-pyrrolizinone-2-methylamino benzoic acid of SFZ-47 were proposed as two potential metabolites and were synthesized.

在动物体内主要代谢途径的确定用HPLC和LC-MS对家兔口服SFZ-47后尿中的代谢物进行了分离、检测，根据代谢产物的色谱和质谱行为以及与SFZ-47有类似结构部分的其它药物的代谢途径，推测其羟基衍生物[4-（3H-1，2-二氢-1-吡咯里嗪酮-2-甲基胺基）苯甲醇]与羧基衍生物[4-（3H-1，2-二氢-1-吡咯里嗪酮-2-甲基胺基）苯甲酸]是两种可能的代谢产物，遂用化学方法合成了这两种衍生物。

The molecules involving azo and imino functional groups can coordinate with Hg2＋ to result in a large blue shift from 453 to 363 nm corresponding to a notable color change from orange to pale yellow in aqueous methanol solution (H2O/CH3OH＝1/4, V/V), which can be applied to naked eye detection of Hg2＋.

这些传感器分子包含偶氮和亚胺功能基团，在水/甲醇溶液（体积比1/4）中，可以与汞离子配位，使紫外-可见光谱中吸收峰发生由453到363 nm的蓝移，引起一个明显的溶液由橙色到淡黄的颜色变化。因而，这些传感器有肉眼检测汞离子的潜在应用。

Deriving conjugated linoleic acid under different condition often leads to incompletability and isomerization.It also affects the accuracy of analysis.

对共轭亚油酸进行三氟化硼-甲醇衍生化时，采用不同条件处理共轭亚油酸，常常导致共轭亚油酸的不完全和异构化，从而影响到分析的准确度。

MeOH extracts of Isatis indigotic of roots and leaves have better anti-oxidant ability.

板蓝根、大青叶的甲醇层萃取物具有较好的抗氧化效果。

A new eucaryotic expression system of recombinant PoIFN-γ was also constructed so that the denaturalization and refolding process is avoided. The target gene coding PoIFN-γ2 mature protein was subcloned into expression vector, transformed into Pichia pastoris, The His〓 Mut〓 phenotype transformants were screened, fermented in flasks and induced by 1％methanol. The expressed product in culture solution and sedimentation have antiviral activity on VSV and immunological activity proved by indirected immunofluorescence antibody and Dot blotting assay.

为了构建可对表达产物修饰、加工的真核表达系统，使表达产物具有自然干扰素的活性，无需变性、复性，我们将PoIFN-γ2成熟蛋白基因连接酵母整合表达载体，电转化毕赤酵母，筛选了His〓Mut〓表型转化子，摇瓶培养，1％甲醇诱导表达，培养上清和菌体裂解上清均有抗VSV病毒活性，经间接免疫荧光抗体检测和Dot blotting鉴定，重组酵母菌诱导表达产物具有免疫活性。

Results demonstrated that the molecular connectivity indices and quantum chemical parameters could be used to predict the k'for 18 substituted indoles, and the molecular connectivity indices MCI method was more accurate.

成功地利用色谱保留预测有机污染物的Kow和Sw等环境行为参数，发现甲醇含量为60%时容量因子同化合物Kow相关性最好。

The results showed that the use of tourmaline could increase alcoholic fermentation speed of molasses, the fermentation speed kept increasing with the increase of the use level of tourmaline, however, as its use level was above 11 %, the increase of fermentation speed was inevident; the use of tourmaline had no side-effects on the content of the main impurities including methanol, n-propyl alcohol, isobutyl alcohol, isoamyl alcohol; though it had weight loss after a period of use, it could still promote alcoholic fermentation of molasses.

结果表明，电气石对提高酵母酒精的发酵速率有促进作用，随着使用量的增加，发酵速率也随着提高，当使用量超过11 %时，发酵速率的继续提高不明显；电气石对发酵过程主要杂质甲醇、正丙醇、异丁醇、异戊醇等没有影响；电气石在使用一段时间后，重量减轻，但仍有促进发酵的作用。

A batch sorption experiments showed that JX-101 had high sorption capacities for benzyl alcohol. While NaCl existed in the solution, equilibrium adsorption data fitted Freundlich isotherms in the studied concentration range, as well as NaCl was inexistent. And the adsorption capacity increased when the content of NaCl rose.

结果表明，JX-101树脂对苯甲醇具有良好的吸附性能，在研究的浓度范围内，吸附平衡符合Freundlich吸附等温式，NaCl存在时不影响吸附等温式的适用，且吸附量随NaCl含量的提高而增大。

Quercetin, quercetin rhamnoside, hyperin, syringoside and eleutheroside E wereisolated from the flower of Acanthopanax senticosus. Searching bioactive natural compound and establishing quality evaluation standard arefocused on this experiment. Using cold immersing of 70% methanol to extract from flower ofAcanthopanax senticosus and integrating macroporous resin, silica gel column chromatography,sephadex gel to abstract. We obtained five monomer compounds (compoundⅠ-compoundⅤ),quercetin, quercetin rhamnoside, hyperin, syringoside and eleutheroside E. That five compoundswere determined by HPLC in eight parts of Acanthopanax senticosus (flower, root, leaf fruit,shoot, new shoot, phloem of shoot, skin of shoot), which provide science bases for establishingquality evaluation system and settle infarctate foundation.

本文以从刺五加花蕾中寻找具有重要生物活性的天然化合物和建立质量评价标准为主要目的，对其化学成分进行研究，采用70％甲醇冷浸的方法对刺五加花蕾中的成分进行提取，运用大孔树脂吸附色谱法、硅胶柱层析法以及葡聚糖凝胶柱层析相结合的方法进行分离，得到5种单体化合物，分别为槲皮素、槲皮素鼠李糖苷、金丝桃苷、紫丁香苷和刺五加苷E；利用高效液相色谱法对这5种化合物在刺五加花蕾中的含量进行了测定；考察了8个部位(花蕾、根、叶、果、茎干、新枝、茎韧皮部、茎皮)中这5种化合物的含量分布情况，并作一比较，为今后建立刺五加质量评价体系提供了科学依据，奠定了坚实的基础。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。