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White nails, found in the accident and loss of blood and shock; chronic diseases are found in anemia, hookworm disease, chronic gastrointestinal bleeding, tuberculosis hemoptysis, pulmonary heart disease and so on; as if a nail white glass, while the characteristics of liver cirrhosis; nail change White, thin, soft, was particularly prevalent in the chronic wasting disease; yellow nail is the lack of vitamin E hypothyroidism, nephrotic syndrome, and other symbolic; gray nails are often suffering from Onychomycosis, a performance for the initial stage next to the itching, Following the nail is deformed, but was dull gray; purple nails with a small red thorn is caused by hypoxia, indicating pulmonary heart disease; nail half red, half white (commonly known as a yin and yang) is not a manifestation of renal function; white nail Flocculation, or white, zinc deficiency may be, anemia or gastrointestinal system is sick; nail spots is the emergence of the performance of the poisoning; redness around the nail, mostly lupus erythematosus and in patients with dermatomyositis; nail root A blue and a half months is a reflection of peripheral circulation; obvious red nails, is the performance of heart failure; a clear and a half months, prompted the digestive system function better absorption; On the other hand, there is no clearance on a narrow or a half months, that is, Tip of the digestive system problems.

指甲变白时,急症见于失血、休克;慢性病则见于贫血、钩虫病、消化道慢性出血、肺结核咯血、肺源性心脏病等;如果指甲白得像毛玻璃一样,则为肝硬化的特征;指甲变白、变薄、变软,多见于慢性消耗疾病;指甲变黄是缺乏维生素E甲状腺功能减退、肾病综合症等象征;指甲变灰往往是患了甲癣,表现为初期甲旁发痒,继则指甲变形,失去光泽而呈灰白色;指甲青紫伴有红色小刺是缺氧引起的,预示肺心病;指甲一半红色、一半白色是肾功能不好的体现;指甲出现白点或絮状白斑,可能是缺锌、贫血或胃肠道系统有病;指甲出现黑斑是中毒的表现;指甲周围出现红斑,多见红斑性狼疮和皮肌炎患者;指甲根部的甲半月呈蓝色是末梢循环不良的反映;指甲明显发红,是心力衰竭的表现;甲半月明显者,提示消化系统吸收功能较好;反之,没有甲关月或甲半月窄小,即提示消化系统有毛病。

The constituents of bulb of F. puqiensis were studied. Five steroid alkaloids were isolated. The plane structure and stereoscopic configuration of 4 compounds were elucidated. They are named as puqienine A (FP-33), puqienine B (FP-3), N-demethyl-puqietinone (〓 FP-34) and puqietinone (〓, FP-9). Puqienine A and N-demethyl-puqietinone are new compounds. Puqienine B is as same as FPQ-3 elucidated by Prof.

对F.puqiensis鳞茎化学成份进行了研究,分得5个甾体类生物碱成分,并采用 UV、IR、EI-MS、1D-NMR,HHCOSY、CHCOSY、HMBC和X-RAY等光谱技术和理化常数测定,鉴定出4个化合物的平面结构和立体构型,分别为蒲圻贝母碱甲(puqienineA,FP-33)、蒲圻贝母碱乙(puqienineB,FP-3)、N-去甲蒲贝酮碱(N-demethyl-puqietinone,FP-34)和蒲贝酮碱(puqietinone,FP-9),其中蒲圻贝母碱甲和N-去甲蒲贝酮碱为新化合物。

The total synthese three natural compounds to explore enantioselective synthesis of flavanol: We use phloroglucin and 2, 4, 6-trihydroxyacetophone as starting materials to synthesis distenin in two ways; Resorcin was used to synthsis 2, 5-dimethoxymethoxyacetophone though 3 steps.

对黄烷醇化合物的立体选择性全合成进行了探索:以间苯三酚和2,4,6-三羟基苯乙酮为原料,尝试用两条路线对Distenin化合物进行了全合成研究;以对苯二酚为原料,经三步制得2,5-二甲氧甲氧基苯乙酮,与2,4,6-三甲氧甲氧基苯甲醛反应,经四步反应得到天然产物3,5,7,2′,5′-二五羟基黄烷关键中间体1-(2′,6′-二甲氧甲氧基苯)-3-(2",4",6-三甲氧甲氧基苯)丙烷-1R,2R-二醇83及其对映体84;简要介绍了EGCg类化合物的生物活性和研究概况。

The charomatographic conditions of separation and direct dermination of benzophenone-4(MS40), salizyle acid sodium, salol, benzophenone-3(M40), octyl dimethyl PABA(6007), butyl methoxy dibenzoyl methane(1789), octyl methoxyl cinnamate and octyl salicylate(587) from u-Bondapak C18 Column were studied with methanol-water-THF as elution. A HPLC method for these compounds was founded.

研究了用甲醇-四氢呋喃-水作为流动相,从C18柱上分离和测定羟苯甲酮-5-磺酸(MS40)、水杨酸钠、水杨酸苯酯、羟苯甲酮(M40)、对-二甲酸氨基苯甲酸-2-乙基己酯(6007)、4-叔丁基-4-甲氧基二苯甲酸甲烷(1789)、对-甲氧基肉桂酸-2-乙基己酯、水氧酸-2-乙基己酯(587)等8种紫外线吸收剂的色谱条件,建立了用HPLC测定上述物质的方法。

Four soluble poly(p-phenylene vinylene) derivatives with asymmetric alkoxyl substituents, poly (2-methoxy-5-butoxy)-p-phenylene vinylene, poly [2-methoxy-5-(3'-methyl)butoxy]-p-phenylene vinylene, poly (2-methoxy-5-hexyloxy)-p-phenylene vinylene and poly (2-methoxy-5-octoxy)-p-phenylene vinylene, were prepared by dehydrochlorination reaction with using p-hydroxyanisole and alkyl bromide as raw materials.

以对羟基苯甲醚和溴代烷烃为原料,采用强碱诱导的脱氯化氢缩合聚合法合成了四种可溶性不对称烷氧基取代聚对苯乙炔衍生物,分别为聚(2-甲氧基-5-丁氧基)对苯乙炔、聚[2-甲氧基-5-(3'-甲基)丁氧基]对苯乙炔、聚(2-甲氧基-5-己氧基)对苯乙炔和聚(2-甲氧基-5-辛氧基)对苯乙炔。

Two novel soluble poly, poly [(3-butyrylpyrrole-2, 5-diyl) p-nitrobenzylidene] and poly [(3-butyrylpyrrole-2, 5-diyl)(3-hydroxy-4-methoxy) benzylidene], were synthesized firstly by condensation of 3-butyrylpyrrole with p-nitrobenzaldehyde and vanillin, respectively.

通过3-丁酰基吡咯单体分别与对硝基苯甲醛和香草醛的缩聚反应,成功合成了两种新型可溶性聚吡咯甲烯衍生物-策[(3-丁酰基吡咯-2,5-二)对硝基苯甲烯]和聚[(3-丁酰基吡咯-2,5-二)(3-羟基-4-甲氧基)苯甲烯]。

Results showed that planktonic Prorocentrum were assembled to onegroup while benthic Prorocentrum were assembled to another group. The percentagesof the bootstrap values were higher than 95%. The results demonstrated that theplanktonic and benthic Prorocentrum should belong to different genus. Furthermore, the resulting phlogenetic structure showed the percentages of thebootstrap values (98%-100%) of Alexandrium in NJ and ML trees were significantlevers and belong to one group, divergently with genus Gonyaulax.

通过分析 17 种甲藻 18S rDNA 序列构建的系统发育树,营浮游生活的原甲藻在显著水平上聚为一类,而底栖种聚为一类,统计置信度均高于 95%,底栖原甲藻和营浮游生活原甲藻在 NJ 树和 ML 树上均为两个分支,且底栖型的分异速度较浮游型迅速,该结果说明原甲藻属中浮游种和底栖种应分属于不同类群。

Results: For the changes of fingernails,it was found that 80 patients(13.33%) had leukonychia punctata,2 leukonychia striata,1 total finger nails dystrophy,4 pitted nails,40(6.67%) variable numbers and degrees of longitudinal crest,transverse grooves or onycholysis.

结果:600例白癜风患者中,80例(13.33%)出现点状白甲,2例出现线状白甲,1例出现双手全指甲营养不良,4例指甲出现点状凹陷,40例(6.67%)出现程度和数量不等的甲横沟、纵嵴或甲分离

The preliminary bioassays indicated that, at 500 g/mL, 1-(o-tolyl-4-(4-chloro-3-ethyl-1-methylpyrazol-5-ylcarbonyl)semicarbazide (4g) and 1-(2,4-dimethyl- phenyl)-4-(4-chloro-3-ethyl-1-methylpyrazol-5-ylcarbonyl)semicarbazide (4k) showed inhibitory activities 90% and 80% against Blumeria graminis, respectively; and at 25 g/mL, 4-phenyl-4-(4-chloro-3-ethyl-1- methylpyrazol-5-ylcarbonylsemicarbazide (4c) showed inhibitory activity 70.1% against Botrytis cinerea and 1-2-nitro-phenyl-4-(4-chloro-3-ethyl-1-methylpyrazol-5-ylcarbonylsemicarbazide (4d) showed inhibi-tory activitiy 51.3% against Pyricularia oryzae.

初步生物活性实验结果表明,在500 mg/mL浓度下,化合物1-(4-氯-3-乙基-1-甲基-1H-吡唑-5-甲酰基)-4-(2-甲基苯基)氨基脲(4g), 1-(4-氯-3-乙基-1-甲基-1H-吡唑-5-甲酰基)-4-(2,4-二甲基苯基)氨基脲(4k)对小麦白粉病菌的抑制率分别达到90%和80%;在25 mg/mL浓度下,化合物1-(4-氯-3-乙基-1-甲基-1H-吡唑-5-甲酰基)-4-苯基氨基脲(4c)对黄瓜灰霉病菌的抑制率达到70.1%;化合物1-(4-氯-3-乙基-1-甲基-1H-吡唑-5-甲酰基)-4-苯基氨基脲(4c)和1-(4-氯-3-乙基-1-甲基-1H-吡唑-5-甲酰基)-4-(2-硝基苯基)氨基脲(4d)对稻瘟病菌的抑制率均达到51.3%。

Unilateral successful number a(K\{1,n\}) has been redefined in this paper: Suppose person a and b contest on complete graph Kp. a first colors one of the edges of Kp green, b then colors another edge red. a and b color the rest edge alternately. a wins the game if what a has colored forms a star K\{1,n\} while b fails to.

给出了一方成功数 a(K\{1,n\})的新定义:甲乙二人在完全图 Kp 上博弈,首先甲用绿色把 Kp 的一条边上色,接着乙用红色染 Kp 的另一条无色边,如此甲乙交替地对 Kp 的无色边进行着色,若甲在 Kp 上染成绿星 K\{1,n\}且乙在 Kp 上没有染成红星 K\{1,n\},甲赢;否则甲输乙赢。

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