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These beetles were identified as belonging to 19 families, among which Carabidae accounted for 30.48%, Staphylinidae 26.97%, Nitidulidae 19.23% of the total, respectively. These three families were dominant groups in the study area because of each more than 10% of the total, respectively. Curculionidae accounted for 9.73 %, Elateridae 5.9%, Chrysomelidae 2.41 % and Scarabaeidae 1.03% of the total.

本研究采集甲虫标本3104号,分属于19科,其中步甲科、隐翅甲科和露尾甲科分别占总数的30.48%、26.97%和19.23%,共同构成了研究地区地表甲虫的优势类群,象甲科、叩甲科、叶甲科和金龟科为常见类群,其余12科为比较不常见的类群。

Three formyl group functional cross-linking polystyrene resins of p -formylphenoxymethyl, p -formyl-2-methoxphenoxymethyl,and p -formyl-3-methoxphenoxymethyl were facilely and rapidly synthesized from Merrifield resin under phase transfer catalytic condition coupling with microwave irradiation in a domestic microwave oven.

以Merrifield树脂为原料,家用微波炉为反应装置,在微波照射的相转移催化条件下,简便快速地合成了3种甲酰基功能化的交联聚苯乙烯树脂——对甲酰基苯氧基甲基树脂、对甲酰基-2-甲氧基苯氧基甲基树脂和对甲酰基-3-甲氧基苯氧基甲基树脂。

Three formyl group functional cross-linking polystyrene resins of methoxphenoxymethyl, and p-formyl-3-methoxphenoxymethyl were facilely and p-formylphenoxymethyl, p-formyl-2-rapidly synthesized from Merrifield resin under phase transfer catalytic condition coupling with microwave irradiation in a domestic microwave oven.

以Merrifield树脂为原料,家用微波炉为反应装置,在微波照射的相转移催化条件下,简便快速地合成了3种甲酰基功能化的交联聚苯乙烯树脂--对甲酰基苯氧基甲基树脂、对甲酰基-2-甲氧基苯氧基甲基树脂和对甲酰基-3-甲氧基苯氧基甲基树脂。

The experiment results indicate that: the increases of catalyst concentration, feed mole ratio of methanol to formaldehyde and the decrease of total feed flow can increase the yield of methylal; the concentration of methylal in distillate also increases with the increase of catalyst concentration; that the effects of reflux ratio on the yield and concentration of methylal in distillate are different from conventional distillation process, an optimal value of reflux ratio exists between 1 and 2 for this process.

实验结果表明:回流比对甲缩醛收率和塔顶甲缩醛纯度的影响不同于一般的精馏过程,存在一个最优回流比,本过程最佳回流比在1-2之间;提高催化剂浓度,甲缩醛收率和塔顶甲缩醛纯度均增加;提高进料醇醛摩尔比也会提高甲缩醛收率;进料总流量对甲缩醛的收率的影响十分明显,进料总流量减少可以使甲缩醛的收率得到明显提高。

Goal compound synthesis namely: Take the vanillic acid as outset raw material, obtains 4- hydroxyl - 3- anisole methyl formate with the methyl alcohol reflux conditions, then after the etherification, the nitration, the return to original state, the ring closure response obtains 6- methoxy - 7- animal pen oxygen radical kui zuo lin - 4- alkone, then passes through the chlorination, the substitution aniline, to escape responses again and so on animal pen oxygen radical, etherification to obtain the goal compound; The goal compound and the diethylamine had the amine substitution reaction to obtain TM1, namely 4- benzene amino - 6- methoxy - 7- [2- hydroxyl - 3-(N, N- two ethyl aminos) third oxygen radical] kui zuo lin; Through zuo has the etherification with the Austria niter to respond obtains TM2, namely 4- benzene amino - 6- methoxy - 7- [2- hydroxyl - 3-(2- methyl - 5- nitryl imidazole) third oxygen radical] kui zuo lin.

目标化合物的合成即:以香草酸为起始原料,与甲醇回流条件下得到4-羟基-3-甲氧基苯甲酸甲酯,然后经过醚化、硝化、还原、环合反应得到6-甲氧基-7-苄氧基喹唑啉-4-酮,然后再经氯化、取代苯胺、脱苄氧基、醚化等反应得到目标化合物;目标化合物与二乙胺发生胺取代反应得到了TM1,即4-苯氨基-6-甲氧基-7-[2-羟基-3-丙氧基]喹唑啉;通过与奥硝唑发生醚化反应得到TM2,即4-苯氨基-6-甲氧基-7-[2-羟基-3-(2-甲基-5-硝基咪唑)丙氧基]喹唑啉。

Synthesis of target compounds namely: to vanillic acid as the starting material with methanol under reflux conditions for 4 - hydroxy -3 - p-methyl, then ether, and nitration, reduction, cyclization reaction 6 - methoxy -7 - benzyloxy-quinazoline -4 - one, and then by the chloride in place of aniline, benzyloxy-off, such as etherification reaction of the target compounds; target compounds with the second and third occurrence of substitution reactions of amines by the TM1, that is, 4 - amino-benzene -6 - methoxy -7 - [2 - hydroxy -3 -(N, N-diethyl amino) oxy c] quinazoline; with ether occurred Ornidazole reaction of TM2, namely, 4 - amino-benzene -6 - methoxy -7 - [2 - hydroxy -3 -(2 - methyl -5 - nitroimidazole) C oxy] quinazoline.

本论文以嘌呤类似物喹唑啉为母核,分别在其4位和7位引入结构多样的取代苯氨基和柔性侧链,设计了一系列4-取代苯胺基-6-甲氧基-7-(2-羟基取代丙氧基)喹唑啉类化合物。目标化合物的合成即:以香草酸为起始原料,与甲醇回流条件下得到4-羟基-3-甲氧基苯甲酸甲酯,然后经过醚化、硝化、还原、环合反应得到6-甲氧基-7-苄氧基喹唑啉-4-酮,然后再经氯化、取代苯胺、脱苄氧基、醚化等反应得到目标化合物;目标化合物与二乙胺发生胺取代反应得到了TM1,即4-苯氨基-6-甲氧基-7-[2-羟基-3-丙氧基]喹唑啉;通过与奥硝唑发生醚化反应得到TM2,即4-苯氨基-6-甲氧基-7-[2-羟基-3-(2-甲基-5-硝基咪唑)丙氧基]喹唑啉。

Five Butenafine's analogues were designed and synthesized according to the structure-activity relationship and operating mechanism of benzylamine antimycotics.

根据苄胺类抗真菌化合物的构效关系、作用机理,设计合成了 5个布替萘芬类似物,N (2 氯 5 吡啶甲基) N 甲基 1 萘甲胺,N ,N 二(4 叔丁基苄基) 1 萘甲胺,N (4 叔丁基苄基) N (2 氯 5 吡啶甲基) 1 萘甲胺,N ,N 二苄基 4 叔丁基苯甲胺,N (2 氯 5 吡啶甲基) N 苄基 4 叔丁基苯甲胺。

Our company supply raw materials and related intermediates as follows: Second dibutyryl cAMP calcium, voriconazole, terbinafine, vecuronium amines, cAMP, thiamphenicol, a chlorophenol hydrochloride esters, card network sodium phosphate tilmicosin, foscarnet, lornoxicam, Tilmicosin, Cephalosporium aspirin acid, ceftiofur hydrochloride, ceftiofur sodium, Ozagrel, ondansetron hydrochloride ketones, hydroxyurea, ticarcillin sodium, telmisartan, esmolol hydrochloride, hydrochloric acid Daguan Nikkomycin, adefovir dipivoxil, buflomedil hydrochloride, granisetron hydrochloride, warfarin sodium,-methyl gabexate acid, nicergoline, pantoprazole sodium,·, tegafur, cefepime hydrochloride, vecuronium bromide, hydrochloric acid meclofenoxate, sertraline hydrochloride, Cefonicid amine salt, aztreonam, ticarcillin, cefdinir, cefodizime sodium, sodium ferulate, colloidal pectin secretion, 2,3 - cyclopentene and pyridine, Piperacillin acid, cefetamet US-acid, hydrochloride Cefmenoxime ,3-TZ, 2 - deoxy-D-glucose, two-amidine urea benzene, sodium Cefonicid, Cefonicid intermediates, ester Cefamandole sodium, Cefalotin acid, intermediates cefpirome, cefepime sulphate, cefepime intermediate nucleus of cefepime, cefpirome nucleus, Cefamandole sodium, ceftriaxone new active ester, oxaliplatin, cyclophosphamide vary gland amines, polyene match him.

我公司供应的原料药及相关中间体为:二丁酰环磷腺苷钙、伏立康唑、盐酸特比萘芬、维库溴胺、环磷腺苷、甲砜霉素、盐酸甲氯酚酯、卡络磺钠、磷酸替米考星、膦甲酸钠、氯诺昔康、替米考星、头孢匹胺酸、头孢噻呋盐酸盐、头孢噻呋钠、奥扎格雷、盐酸恩丹西酮、羟基脲、替卡西林钠、替米沙坦、盐酸艾司洛尔、盐酸大观霉素、阿德福韦酯、盐酸丁咯地尔、盐酸格拉司琼、华法林钠、甲磺酸加贝酯、尼麦角林、泮托拉唑钠、普拉洛芬、替加氟、盐酸头孢吡肟、维库溴铵、盐酸甲氯芬酯、盐酸舍曲林、头孢尼西胺盐、氨曲南、替卡西林、头孢地尼、头孢地嗪钠、阿魏酸钠、胶体果胶泌、2,3-环戊烯并吡啶、哌拉西林酸、头孢他美酸、头孢甲肟盐酸盐、3-TZ、2-脱氧-D-葡萄糖、双脒苯脲、头孢尼西钠、头孢尼西中间体、头孢孟多酯钠、头孢噻吩酸、头孢匹罗中间体、头孢吡肟硫酸盐、头孢吡肟中间体、头孢吡肟母核、头孢匹罗母核、头孢孟多钠、头孢曲松新型活性酯、奥沙利铂、异环磷腺胺,多烯他赛。

The main subtypes of onychomycosis are distal lateral subungual onychomycosis, white superficial onychomycosis, proximal subungual onychomycosis, endonyx onychomycosis, and candidal onychomycosis.

甲真菌病的主要亚型是远端外侧甲下甲癣(康乐事务办事处或DSO),白色表面的甲真菌病,近端甲下甲真菌病的,endonyx甲真菌病和念珠菌甲癣。

For the pentagonal, the fifth block fan-shaped, and the remaining three triangular rib angle plate on each side 4, edge angle plate 11 on each side; carapace brown, with three black longitudinal edges; shell and black, its edge angle plate with yellow; both sides of the carapace and the plastron to ligaments connected plastron in the chest, abdomen corner cubicle of the ligaments connected to the Trans-Yi Yi; means, and between the toes with webbed; tail short and pointed.

金钱龟的外型特征是头部光滑无鳞,鼓膜明显而圆;颈角板狭长,椎角板第一块为五角形,第五块呈扇形,余下3块呈三角形,肋角板每侧4块,缘角板每侧11块;背甲棕色,具3条黑色纵棱;腹甲黑色,其边缘角板带黄色;背甲与腹甲两侧以韧带相连,腹甲在胸、腹角板间亦以横贯的韧带相连;指和趾间具蹼;尾短而尖。

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