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甲状旁腺功能亢进

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Objective To study the effect of parathyroid cells proliferation and apoptosis in severe renal secondary hyperparathyroidism.

目的 探讨甲状旁腺细胞增生和凋亡在严重肾性继发性甲状旁腺功能亢进发病机制中的作用。

Objective: To investigate the application and criteria of intraoperative parathyroid hormone assay during surgery of secondary hyperparathyroidism.

目的:探讨甲状旁腺激素测定在继发性甲状旁腺功能亢进手术中的应用和标准。

Objective To observe the curative effect of total parathyroidectomy with forearm autograft on the uremic patients suffering from severe secondary hyperparathyroidism.

目的 观察甲状旁腺全切除加自体前臂移植术治疗尿毒症维持性透析患者严重继发性甲状旁腺功能亢进的临床疗效。

Objective To evaluate the changes in bone mass and markers of bone metabolism and the clinical manifestations in patients with primary hyperparathyroidism after parathyroidectomy.

原发性甲状旁腺功能亢进可引起人体钙磷代谢紊乱,其后果可导致继发性骨质疏松、骨痛、骨折及骨骼畸形,严重影响患者的生活质量。

The Ca level was also significantly decreased after the operations but it only had statistic significances in group Ⅰ. Conclusion Both subtotal parathyroidectomy and total parathyroidectomy with parathyroid tissue transplantation in the forearm have therapeutic effects for renal secondary hyperparathyroidism and the effects had no significant differences in the short term.

对内科治疗无效的肾性继发性甲状旁腺功能亢进患者,甲状旁腺次全切除术及甲状旁腺全切+前臂移植术都是有效的治疗方法,且两种手术方式在术后短期内(术后1天及6个月)的治疗效果无统计学差异。

To overcome this potential problem in some cases of hyperparathyroidism, the assay must be carried out in multiple dilutions of the serum sample to fully assess the PTH level.

为了克服这个问题,在部分甲状旁腺功能亢进的病人中,血样必须先经过稀释,才能测定甲状旁腺素。

Objective and Methods:The size of parathyroid gland in 52 patients who received long term hemodialysis were measured with ultrasonography and compared with normal control.

目的:探讨B型超声对继发性甲状旁腺功能亢进的诊断价值。方法:选择52例不同时期维持性血液透析患者,应用B型超声测算甲状旁腺体积,并与正常人对照。

Also, cinacalcet, a new medication that stimulates the calcium sensing receptor in the parathyroid gland and causes negative feedback on PTH production and release, can be used to treat secondary hyperparathyroidism.

另外4,这些新的维生素D类似物的事业少血清钙,磷浓度升高。5此外,cinacalcet,一个新的刺激的药物检测中的钙甲状旁腺受体,造成对生产和释放甲状旁腺负反馈,可用于治疗继发甲状旁腺功能亢进

Hypocalcemia stimulates the parathyroid gland to excrete PTH, a process termed secondary hyperparathyroidism.

低血钙刺激甲状旁腺分泌甲状旁腺素的,这个过程被称为继发甲状旁腺功能亢进

All patients with secondary osteoporosis caused by all endocrine diseases including Cushing's disease, hyperthyrosis, hyperparathyroidism, capsula glandulae thyroideae or thyroid hypofunction and diabetes, and patients whose bone metabolism was interfered by grave diseases were excluded. Three months before the trial, the patients did not receive any drug that could interfere the bone metabolism or affect endothelin, such as estrogenic hormone, calcitionin, nitrogen monoxidum, glucocorticoid. In addition, the patients suffering from bone fracture within 1 year or grave cardio-cerebrovascular disease, which had intimate correlation with endothelin, liver and kidney disfunction were eliminated.

所有纳入病例均排除以下患有引起继发性骨质疏松症的各种内分泌疾病者(如柯兴氏病、甲状腺功能亢进、甲状旁腺功能亢进、甲状腺囊肿或机能低下、糖尿病等);其他严重疾病干扰骨代谢者;测试前3个月内未使用过雌激素、降钙素、一氧化氮、糖皮质激素等干扰骨代谢或对内皮素有影响作用的药品;测试前1年内无骨折;患有严重心脑血管等与内皮素水平相关密切之疾病及肝肾功能异常者。

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