甲基苯胺

A process for preparingp-fluo-2-(2-methyl-3-propionyl)-4-oxy-N,3-diphenyl-phenylbutylamide includes such steps as Friedle-Craft acylating of newly prepared phenylacetyl chloride and fluorobenzene under catalysis of AlCl3 to obtain 4-fluoro-phenylbenzyl ketone, brominating at carbonyl alpha position under catalysis of less AlCl3 to obtain alpha-bromo-4-fluo-phenylbenzyl ketone, and condensing with isobutyryl acetanilide under action of sodium ethoxide.

本发明涉及一种制备对氟－2－(2－甲基－3－氧丙基)－4－氧－N，3－二苯基－苯丁酰胺(1)的方法，其包括以下步骤：新制的苯乙酰氯与氟苯在AlCl3催化下进行Friedle－Craft酰化反应，得到对4－氟－苯基苄基酮(4)；化合物(4)在少量AlCl3催化下进行羰基α位溴化，得到α－溴－4－氟－苯基苄基酮(5)；然后(3)异丁酰乙酰苯胺在乙醇钠作用下与化合物(5)进行缩合。

Methods Tarry stools from 38 cases definited upper gastrointestinal bleeding and 16 stomach strains confirmed including red blood cells by test under microscope respectively tested by colloidal gold indicator paper, orthotolidine method and tetramethyl benzidine indicator paper.

将38例临床确诊为上消化道出血患者的&柏油&样粪便和16份经镜检证实含红细胞的胃引流物标本分别用胶体金试纸、邻联甲苯胺和四甲基联苯胺尿隐血试纸测试其是否含有隐血。

Adsorpytion of congo red and crystal violet can be described using the Langmuir isotherm, on the other hand, adsorption of methylene blue and aniline blue can be described using a Freundlich isotherm.

对刚果红和结晶紫的吸附服从Langumir吸附等温线，而对于亚甲基蓝和苯胺蓝的吸附则服从Freundlich吸附等温线，图4，表2，参9。

Second, the solthe solthe sol-gel solution did not contain alcohol, instead, poly methyl methacrylate, aniline and phosphate salt(calcium phosphate dibasic, manganese phosphate or zinc phosphate) were added.

第二部分是在未加入酒精的状况下，将有机高分子聚甲基丙烯酸甲酯(poly methyl methacrylate， PMMA)加入含有磷酸盐(磷酸氢钙、磷酸锰或磷酸锌)的溶胶中，并利用苯胺的催化，得到奈米级的有机-无机复合皮膜。

TpRu(PPh3)(CH3CN)2PF6 (10mol%) catalyst effected the nucleophilic addition of water,alcohols,aniline, acetylacetone, pyrroles, and dimethyl malonate to unfunctionalized enediynes under suitable conditions (100 °C, 12 24 h) and gave functionalized benzene products in good yields.

TpRu 2PF6 （ 10mol ％）催化剂的影响的亲核加成的水，醇，苯胺，丙酮，吡咯和二甲基丙二酸对unfunctionalized enediynes适当的条件下（ 100 ℃， 12日24小时），并官能苯产品良好的收益。

Optimum conditions are as follows: DMF is used as solvent, compound quaternary ammonium salt as catalyst, n(p-nitrochloro benzene):n=1: 1.2, m:m(p-nitrochloro benzene)=4%, m:m(p-nitrochloro benzene)1:1, and reacted under 155~160℃ for 18 h; reduction reaction is carried out in methanol with Raney nickel, which is used as catalyst; the raw product is added an antioxidant, and distilled simply under reduced pressure to obtain 4-fluoroaniline with excellence quality, purity is over 99.5%, total yield is 89.3%.

实验结果表明，氟化反应的最佳条件为：二甲基甲酰胺为溶剂、复合季铵盐为催化剂，n：n=1：1.2，m（催化剂：m=4%，m：m=1：1，于155~160℃下反应18h；还原反应在甲醇中进行，以阮内镍为催化剂；粗产品加入抗氧剂，减压条件下简单蒸馏得高品位的对氟苯胺。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。