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甲基吡啶

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In chapter three, molecular imprinting chiral stationary phases against amino acid derivatives utilizing 2-vinylpyridine+acrylamide (2-VP+AM) as combined functional monomers were prepared. Comparing combined functional monomer 2-VP+AM with AM and methacrylic acid+2-VP, the former, 2-VP+AM showed higher imprinting ability. Explanation was given according to the compatibleness between the functional monomer and the imprinted molecule.

第三章系统考察了复合功能单体2-乙烯基吡啶+丙烯酰胺制备氨基酸衍生物分子烙印手性固定相的情况,发现复合功能单体2-乙烯基吡啶+丙烯酰胺烙印体系与丙烯酰胺及复合功能单体2-乙烯基吡啶+甲基丙烯酸烙印体系相比,对氨基酸衍生物表现出更好的烙印能力,验证了功能单体与烙印分子之间存在着匹配性的观点。

Main products include: 1,3-dimethyl-2-imidazolone, also named dimethyl-ethenylurea, 1,3-Dimethyl-2-imidazolone、1,3- Dimethyl-3,4,5,6- four hydrogen-2-pyrimidone, 2-imid-azolidinone、methane acid amine,、pyridylmethanol、pyridylaldehyde、50% methane acid,etc series products.

公司主营:1,3-二甲基-2-咪唑啉酮,又称二甲基乙烯脲,1,3-Dimethyl-2-imidazolinone、1,3-二甲基-3,4,5,6-四氢-2-嘧啶酮、 2-咪唑啉酮、甲酸胺、吡啶甲醇、吡啶甲醛、50%甲酸等系列产品。

Main products include: 3-Dimethyl-2-imidazolidinone, also named dimethyl-ethenylurea, 3-Dimethyl-2-imidazolidinone、1,3- Dimethyl-3,4,5,6- four hydrogen-2-pyrimidone, 2-imid-azolidinone、methane acid amine,、pyridylmethanol、pyridylaldehyde、50% methane acid,etc series products.

公司主营:1,3-二甲基-2-咪唑啉酮,又称二甲基乙烯脲, 1, 3-Dimethyl-2-imidazolidinone、1,3-二甲基-3,4,5,6-四氢-2-嘧啶酮、 2-咪唑啉酮、甲酸胺、吡啶甲醇、吡啶甲醛、50%甲酸等系列产品。

Mission:"equality and mutual benefit, reputation first, unity and cooperation and friendship between the long-term" supply products: ethylenediamine; diethylamide; triethylamine; Diethylenetriamine; three ethylene diamine; three ethylene amines 40; 40 Five ethylene amines; five ethylene amines 6; caprolactam; DMF; allyl amine; N, N dimethylaniline; propylamine; are butylamine; are TOA; 3 Poly Cyanamide; 1,2 c diamine; ethanolamine; diethanolamine, triethanolamine; potassium iodide, potassium hydroxide, potassium permanganate, toluene, xylene, toluene of chlorine ; Acetone, butanone; acetylacetone; ethyl acetate, butyl acetate; Y-butyrolactone; DMC; acetyl of methyl acetate; Sanfu acetyl acid; Sanfu acetyl B Ethyl; methanol, ethanol, isopropanol; propylene glycol; glycerol; propargyl alcohol; 1.3 propylene glycol; xylitol; acetic acid; have acid; mercaptoacetic acid; vary Bitterness; adipic acid; trifluoroacetic acid; oxalic acid, the amino acid; o-amygdalin acid; DL-Acid; anhydrous piperazine; six non-piperazine, furfural, castor oil, ethylene Aldehyde; glutaraldehyde, multi-POM; isopropyl ether; anisole; tetrahydropyrrole; pure pyridine; 1.2 dichloroethane; methylene chloride, chloroform, carbon tetrachloride; hydrazine hydrate; Nonylphenol;-m-cresol; Se phenol; phenol; the tert-butyl phenol; Titanium Dioxide; iron; full Tangfen; Bisphenol A; azo two different nitrile; sodium azide; sodium carbonate ; Sodium chloride; iron oxide; cuprous chloride; thionyl chloride; D4; sodium bicarbonate; ammonia, potassium chloride; anhydrous sodium sulphite; ammonium persulfate; glycol Dingmi; B Glycol ether; calcium chloride; cyclohexanone; cyclohexane, methyl tertiary butyl ether, potassium carbonate, ferric chloride, potassium nitrate; Linsuansanna; zinc oxide; sodium nitrite; antimony oxide; Tartrate; OP-10; TX-10; tablets base; AES; sodium benzoate, sodium citrate; partial sodium silicate, sodium perborate, a sodium carbonate, sodium benzene; Asia sodium chlorate; Wuluo Care products; urea; hydrochloric acid, sulfuric acid, lactic acid; amino acid, hydrogen peroxide, ammonium bicarbonate

公司宗旨:"平等互利,信誉至上,团结合作,友谊长久"乙二胺;二乙胺;三乙胺;二乙烯三胺;三乙烯二胺;三乙烯四胺;四乙烯五胺;五乙烯六胺;己内酰胺;二甲基甲酰胺;烯丙基胺;N,N二甲基苯胺;正丙胺;正丁胺;正辛胺;三聚氰胺;1,2丙二胺;一乙醇胺;二乙醇胺;三乙醇胺;碘化钾;氢氧化钾;高锰酸钾;甲苯;二甲苯;对氯甲苯;丙酮;丁酮;乙酰丙酮;醋酸乙酯;醋酸丁酯;Y-丁内酯;碳酸二甲酯;乙酰乙酸甲酯;三伏乙酰乙酸;三伏乙酰乙酸乙酯;甲醇;无水乙醇;异丙醇;丙二醇;丙三醇;丙炔醇;1.3丙二醇;木糖醇;冰醋酸;己醛酸;巯基乙酸;异辛酸;己二酸;三氟乙酸;乙二酸;对氨基苯乙酸;邻氯苦杏仁酸;DL-扁桃酸;无水哌嗪;六无哌嗪;糠醛;蓖麻油;乙二醛;戊二醛;多聚甲醛;异丙醚;苯甲醚;四氢吡咯;纯吡啶;1.2二氯乙烷;二氯甲烷;三氯甲烷;四氯化碳;水合肼;壬基酚;纯间甲酚;硒酚;苯酚;对叔丁基苯酚;钛白粉;铁粉;全糖粉;双酚A;偶氮二异丁腈;叠氮化钠;碳酸钠;氯化钠;三氧化二铁;氯化亚铜;氯化亚砜;D4;碳酸氢钠;氨水;氯化钾;无水亚硫酸钠;过硫酸铵;乙二醇丁醚;乙二醇乙醚;氯化钙;环己酮;环己烷;甲基叔丁基醚;碳酸钾;三氯化铁;硝酸钾;磷酸三钠;氧化锌;亚硝酸钠;氧化锑;酒石酸;OP-10;TX-10;粒碱;AES;苯甲酸钠;柠檬酸钠;偏硅酸钠;过硼酸钠;过碳酸钠;苯磺酸钠;亚氯酸钠;乌洛托品;尿素;盐酸;硫酸;乳酸;氨基磺酸;双氧水;碳酸氢铵

Two kinds of dsDNA intercalating fluorescent dyes, [Ru2]2+(phen = 1,10-phenanlinthroline; dppz = dipyrido [3,2-a:2',3'-c] phenazine) and BOBO-3 2,2\'-1,3-propanediylbis[(dimethyliminio-3,1-propanediyl -1(4H)-pyridinyl-4-ylidenemethy-lidynebis[3-methyl]-benzothiazoe were employed in this chapter, and two non-covalent labeled fluorescence sensing systems for thrombin determination were successfully developed and compared based on its 29-mer aptamer.

本章利用dsDNA嵌入式荧光染料[Ru2]2+(phen = 1,10-二氮菲; dppz =吡啶[3,2-a:2',3'-c]吩嗪)及BOBO-32,2\'-1,3-丙二基二[(二甲基亚氨基-3,1-丙二基-1(4H)-吡啶基-4-(丙-1,3-二烯基二[3-甲基]-苯并噻唑),基于适配体29-mer,分别建立了两种凝血酶检测体系[Ru(phen2]2+及BOBO-3检测体系。

This invention is directed to the-tartaric acid salt of 2-amino-N-{1-(2,4-difluoro-benzyloxymethyl)-2-oxo-2-3-oxo-3a-pyridin-2-ylmethyl-2-(2,2,2-trifluoroethyl-2,3,3a, 4,6,7-hexahydro-pyrazolo(4,3-c) pyridin-5-yl-ethyl}-2-methyl-propionamide which is a growth hormone secretagogue and as such is useful for increasing the level of endogenous growth hormone.

本发明涉及2-氨基-N-{1--(2,4-二氟-卞氧甲基)-2-氧代-2-3-氧代-3a-(R-吡啶-2-基甲基-2-(2,2,2-三氟-乙基)-2,3,3a,4,6,7-六氢化-吡唑子基(4,3-c)吡啶-5-基-乙基}-2-甲基-丙酰胺的--酒石酸盐,它是一种生长激素促分泌素,并且可用于提高内源性生长激素水平。

Hrough copolymerization of styrene with few quantity of methacrylic acid, maleic anhydrate or 4-vinyl pyridine respectively and of butyl methacrylate with maleic anhydrate, the functional groups carboxyl, simple anhydride and pyridyl have been introduced respectively to the chain of PS or PBma.

通过苯乙烯与少量的甲基丙烯酸、马来酸酐或4—乙烯基吡啶的共聚及甲基丙烯酸正丁酯与马来酸酐的共聚,可在聚苯乙烯及聚甲基丙烯酸丁酯链上分别引入功能基因羧基、酸酐基和吡啶基对共聚物进行了红外光谱、酸碱滴定、元素分析、玻璃化转变温度、粘度及紫外光谱的测定。

In this paper, the host-guest relationship between a general cucurbit [n=7] uril (Q[7]) or a new ellipsoid-host-symmetric tetramethyl-cucurbituril (TMeQ[6]) with hydrochloride salts of 4,4'-dipyridyl (44) or N,N'-dimethyl-4,4'-dipyridyl(dm44) was examined for confirming the interaction between cucurbituril (Q[6]) and these guests.

以七元瓜环(Q[7])和新型椭圆型改性瓜环―对称四甲基取代六元瓜环(TMeQ[6])为主体,4,4'-联吡啶的盐酸盐(44)以及N,N'-二甲基4,4'-联吡啶的盐酸盐(dm44)为客体的主客体相互作用进行了考察。

Methods:2-Hydroxy-4-methyl-3-nitropyridine was reacted with phosphorous pentachloride to give 2-chloro-4-methyl-3-nitropyridine.

以4-甲基-3-硝基-2-羟基吡啶为起始原料,与五氯化磷进行卤代反应制得4-甲基-3-硝基-2-氯吡啶。

A compound of formula wherein R1 is hydrogen, halo or methoxy; R2 is hydrogen, halo, methyl, ethyl or methoxy; R3 is carboxy, tetrazolyl, or -CONHSO2R where R is methyl, ethyl, phenyl, 2,5-dimethylisoxazolyl or trifluoromethyl; T is -CH2- or -SO2-; and ring A is 3-chlorophenyl, 4-chlorophenyl, 3-trifluoromethylphenyl, 3,4-dichlorophenyl, 3,4-difluorophenyl, 3-fluoro-4-chlorophenyl, 3-chloro-4-fluorophenyl or 2,3-dichloropyrid-5-yl; or a pharmaceutically acceptable salt or prodrug thereof, as well as pharmaceutical compositions containing them are described and claimed.

本发明涉及一种式化合物,其中R 1 是氢原子、卤素或甲氧基;R 2 是氢原子、卤素、甲基、乙基或甲氧基;R 3 是羧基、四唑基或-CONHSO 2 R 4 ,其中R 4 是甲基、乙基、苯基、2,5-二甲基异∴唑基或三氟甲基;T是-CH 2 -或-SO 2 -;环A是3-氯苯基、4-氯苯基、3-三氟甲基苯基、3,4-二氯苯基、3,4-二氟苯基、3-氟-4-氯苯基、3-氯-4-氟苯基或2,3-二氯吡啶-5-基;或其药用允许的盐或前药,还包括所阐述和要求权利的含有它们的药用组合物。

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