甲基吡啶

A method for determination of basic nitrogen-containing compounds in mainstream smoke was established. In the condition of basic substance barium hydroxide powder and extractant chloroform, 18 basic nitrogen-containing compounds were analyzed by gas chromatography-selective ion monitored-mass spectrometry, such as pyridine, 2-methylpyridine, 2-methylpyrazine, quinoline and indole, etc.

在氢氧化钡碱性环境中，以三氯甲烷为萃取剂，采用气相色谱－选择离子监测－质谱法测定吡啶、2-甲基吡啶、2-甲基吡嗪、喹啉、吲哚等18种碱性含氮化合物。

Methods Starting from 2-chloro-4-nitrophenol and 2- pyridine hydrochlorid, 3-chloro-4-(pyridin-2-ylmethoxy) aniline was obtained via etherization and reduction. The obtained aniline coupled with N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl) acetamide to give 4-[3-chloro-4-(2-pyridylmethoxy) phenylamino]-3-cyano-7-ethoxy-6-N-acetylaminoquinoline. And then it was deacetylated, followed by reacting with4- but-2-enoyl chloride to yield the target compound neratinib.

以2-氯－4-硝基苯酚和2-氯甲基吡啶为起始原料，经醚化、硝基还原得到3-氯－4-（吡啶－2-甲氧基）苯胺，3-氯－4-（吡啶－2-甲氧基）苯胺与3-氰基－6-乙酰氨基－7-乙氧基－4-氯喹啉反应得到3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉，3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉去乙酰保护基后，与-4-二甲氨基－2-丁烯酰氯经酰化反应得到ner-atinib。

Cobalt forms colored complexes with pyridire,,β-picoline and γ-picoline in aqueous solutions.

在水溶液中鈷和吡啶，3-甲基吡啶，4-甲基吡啶形成紅色的1：1絡离子。

Picoline was treated with hydrogen peroxide to form intermediate N-oxide-3- methylpyridine then chloridized with benzoyl chloride to form 2-chloro-5-methylpyridine.

以3-甲基吡啶为原料通过过氧化氢氧化得中间产物3-甲基吡啶-N-氧化物，再用苯甲酰氯氯化得到粗产品2-氯-5-甲基吡啶。

Based on broad information collection, author compared and studied on the old synthesis process, and proposed the better process that started from benzyl chloride, then according to the sequence of " synthesis of benzylamine, synthesis of N-benzyl-N--acetamine, synthesis of 2-chloro-5-methylpridine ,2-chloro-5-trichloromethylpyridine,2-chloro-5-trifluropyridine " five steps to get the final product, CTFP.

本文在查阅大量文献资料和对2-氯-5-三氟甲基吡啶合成路线进行分析比较的基础上，提出了较佳合成路线，即以氯化苄为原料，合成的反应步骤为&苄胺&合成、&N-苄基-N--乙酰胺&合成、&2-氯-5-甲基吡啶&合成、&2-氯-5-三氯甲基吡啶&合成、&2-氯-5-三氟甲基吡啶&合成五步。

Benzylidene[1,3-bis(2,6-dimethylphenyl)-4,5-dihydroimidazol-2-ylidene]dichloro(2-methylpyridine)ruthenium (62), benzylidene[1,3-bis(2,6-dimethylphenyl)-4,5-dihydroimidazol-2-ylidene] dichloro(2,4-dimethylpyridine)ruthen ium (63) introduce ortho substituted pyridine as dissociating ligand to weaken Ru-N bondand accelerate dissociation of pyridine derivative ligand through steric hindrance.

在钌卡宾配合物[1，3-二-(2，6-二甲苯基)-4，5-二氢咪唑基]-苯亚甲基-(2-甲基吡啶)-二氯合钌(62)，1，3-二-(2，6-二甲苯基)-4，5-二氢咪唑基1-苯亚甲基-(2，4-二甲基吡啶)-二氯合钌(63)中，邻位取代的吡啶作为解离配体，通过邻位基团的空间效应削弱钌-氮配位键，使配体更易解离，提高了催化剂的初活性。

But on the industry, many with the alkyl bandaging, such as bandaging , ergadebidi...

但是在工业上，多以烷基吡啶，如3-甲基吡啶、2-甲基-5-乙基吡啶以及喹啉等为原料制备烟酸。

Based on the research and development of synthesis of halogenated pyridines the paper chose the electrochemical reduction as a research direction, and to 3,4,5,6–tetrachloropicolinic acid, pentachloropyridine, 3,4,5,6-tetrachloro-2-trichloromethylpyridine for raw materials, the reduction behavior on silver and carbon -containing silver electrode was mainly studied.

全卤吡啶脱氯是卤代吡啶类化合物合成的新尝试，本文在国内外卤代吡啶合成研究的基础上，选择了以电化学还原作为研究方向，以3，4，5，6-四氯吡啶甲酸、五氯吡啶、3，4，5，6-四氯-2-三氯甲基吡啶为原料，主要研究了其在银和碳载银电极上的还原行为。

A process for synthesis of-2-{[4-(3-methoxypropoxy)-3-methyl-pyridin-2-yl]methyl- sulfinyl}-1H-benzimidazole from 2,3-lutidine was studied.

以2，3-二甲基吡啶为起始原料，经过11步反应，不对称合成了质子泵抑制剂的关键中间体：-2-{[4-(3-甲氧基丙氧基)-3-甲基吡啶-2-基]甲基亚硫酰基}-1H-苯并咪唑。

The effects of pyridine substitutive derivations on the metabolic pathway of Blakeslea Trispora, were studied such as 2,6-dimethylpyridine,2,5-dimethylpyridine, 2-amino-6-methylpyridine and tobacco dust which contains mainly 3-pyridine substitutive derivation.

主要考察了吡啶衍生物如2，6-二甲基吡啶、2，5-二甲基吡啶、2-氨基-6-甲基吡啶及烟草废弃物（主要成分为3-吡啶基衍生物）对三孢布拉氏霉菌代谢途径的影响。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失