甲基化的

Objective To study the effect of betaine on the DNA methylation in HepG2 genome.

目的研究甜菜碱对人肝癌细胞HepG2内基因组范围DNA甲基化的影响。

A series of diazonium salts of 4-(N-methyl-N-phenylamino)-3-amino-1,8-naphthalic anhydride 5a, its naphthalimide derivative 5b, and 5e were designed and synthesized,and it was the first time to discover that aromatic radical-induced intramolecular aromatic 1, 5-hydrogen transfer was also involved in the nitrogen-contianed system during Pschorr cyclization.

实验设计合成了4--3-氨基-1，8-萘酐的重氮盐5a、其衍生物N-丁基-4--3-氨基-1，8-萘酰亚胺的重氮盐5b和N--4--3-氨基-1，8-萘酰亚胺的重氮盐5c，并首次发现了通过普朔尔环化反应以氮甲基化的氮为桥原子的体系存在着芳香自由基诱导的芳香1，5-氢转移。

However, accidental changes in DNA methylation can be transmitted through mitosis or meiosis, leading to epiallelic variation.

但是，DNA甲基化的意外变化能够通过有丝分裂或减数分裂，导致表观变异。

Moreover, we could accomplish such silencing in a cancer cell line genetically modified to lack virtually any capacity to methylate DNA.

此外，在经过遗传改变导致无法发生DNA甲基化的癌细胞系中，我们能够成功地再现这一沉默机制。

The metals which are of particular concern are those which have been shown to be methylated in nature.

人们特别关心那些在自然界能被甲基化的金属。

Using chemical treatment, the kit converts all unmethylated cytosine residues to uracil.

使用化学处理，该套件会将所有未甲基化的胞嘧啶残留尿嘧啶。

The analysis of DNA methylation in plasma will have the powerful potentiality that applicate to noninvasive prenatal diagnosis.

血浆DNA甲基化的分析进一步应用于无创性产前诊断具有可行性。

Objective To probe into the situation and significance of p16 gene mutation and methylation in patients with arseniasis caused by coal-burning pollution.

目的 了解抑癌基因p16在燃煤型砷中毒患者中突变及甲基化的情况和意义。

Objective To probe into the situation and significance of p16 gene CPG island methylation in patients with arseniasis caused by coal-burning pollution.

目的了解抑癌基因p16启动子区CPG岛在燃煤型砷中毒患者中甲基化的情况和意义。

As we have knowen that,DNA methylation is associated with transcriptional silencing of tumor suppressors or other genes important for normal cellular function and plays an important role in the development of gastrointestinal tumor.

随着对DNA甲基化的分子机制的进一步认识，以甲基化为基础的标志在临床的应用，尤其是肿瘤的防治，展现了广阔的前景。

Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在，'歼灭战perfuming自己与胡努特，那麼，他来到和SAT 。