甲基化的

These results indicated some differences from other investigated autopolyploid plants in autopolyploid watermelon. Autotriploid watermelon, in particular, showed unusual characters of genome structure and DNA methylation status, which may be closely associated with the oddploidy effect and the excellent traits present in triploid plants.

综上结果证明，西瓜同源多倍化过程中发生的遗传和表观遗传改变与已报导的一些植物的同源多倍化有所不同，特别是三倍体西瓜，其表现出独特的基因组结构及DNA甲基化状态变化特徵，而这可能与植物的奇倍性效应及三倍体西瓜优良性状的形成密切相关。

The two—step sulfomethy lation and the reaction with HOCH〓SO〓Na in sulfite cooking were illustrated in this paper. The optimum technological conditions were determined on the basis of suitable amount of HCHO in sulfite pulping. The differences of delignification and paper properties of wheat straw were also studied in SFP—AQ and alkaline sulfite and AQ cooking .

对麦草粉的两步法磺甲基化反应以及与羟甲基磺酸钠的反应进行了研究，解释了甲醛在亚硫酸盐蒸煮中脱木素作用机理，从理论上确定了甲醛在SFP—AQ蒸煮中的适宜用量，并据此提出了合理的蒸煮工艺和最佳工艺条件。

Hydroxy-5, 10-dihydrophenophosphazine 10-oxide (1) reacted with SOCl2, and then with MeONa in MeOH to give a methyl phosphinate (2) which can be converted to a dinitro compound 3 (62%) by nitration and the resulting dinitro compound 3 can further be converted to 2, 8-diamino-10-methoxy-5, 10-dihydrophenophosphazine 10-oxide (4, 71%) by hydrogenation over Pd/C (w = 0.05). And the effect of amount of Pd/C (w = 0.05) on the reduction was also studied.

10－羟基－5，10－二氢磷杂吖嗪－10－氧化物（1）经醯氯化、甲基化得到10－甲氧基－5， 10－二氢磷杂吖嗪－10－氧化物（2），2经硝化得到10－甲氧基－2，8－二硝基－5，10－二氢磷杂吖嗪－10－氧化物（3，62%）。3在Pd／C（w = 0.05）存在下，用氢气还原为2，8二氨基－10－甲氧基－5，10－二氢磷杂吖嗪－10－氧化物（4，71%），考察了Pd／C（w = 0.05）用量对氢化还原反应的影响。

One route was that the amino-groups on the silica gel were transformed to tertiary amines by Eschweiler-clarke reaction that amine-groups react with formaldehyde and methanoic acid to prepare tertiary amines; the silica gel intermediates with tertiary amine groups reacted with chorohydrocarbons to prepare insoluble silica gel quaternary ammonium salt bactericides. Another route was that the amino-groups on the silica gel reacted with excessive chlorohexadecane; the preparing intermediates were quaternized with iodomethane to obtain insoluble silica gel quaternary ammonium salt bactericides.

一条路线是根据埃施韦勒-克拉克(Eschweiler-clarke)胺甲基化反应，进行胺基叔胺化反应，制成带有叔胺官能团的硅胶中间体，此中间体上的叔胺与卤代烷反应生成杀菌活性官能团季铵盐，制成硅胶类水不溶性季铵盐杀菌剂；另一条路线是带有胺反应活性中心的硅胶与过量正氯代十六烷反应，得到的中间体再用碘甲烷季铵化，得到最终产品——水不溶性季铵盐杀菌剂。

Still identified another kind of H3K27me3 recently only the gender goes methylic enzymatic Jumoji3(JMJD3). Of H3K27 2 and 3 methylic change intention, basically be to be located in development adjustment gene (start mover division like what Hox) gene forms a cluster.

最近还识别了另一种H3K27me3的专性去甲基酶jumoji3(JMJD3)。H3K27的2和3甲基化功能，主要是位于发育调节基因基因簇的启动子区。

P16 gene is composed of two intervening sequences and three exons , and encodes p16 protein , which is the inhibiter of CDK4 and CDK6 . They can together prevent phosphorylation deactivation of pRB , and make the cell cycle blocked in G1 stage. P16 gene promoter region has a great of CpG islands , which can be methylated when some adverse factor appears , and so the genetic transcription of p16 can be inhibited , which leads to gene silencing, cell paraplasm, and tumor generate.

抑癌基因p16编码蛋白P16 ，是细胞周期蛋白CDK4和CDK6抑制剂，它阻止pRB磷酸化失活，使细胞周期阻滞于G1期。P16基因启动子区域富含CpG岛，当受到各种有害因素影响时，容易发生甲基化，从而抑制P16基因转录，导致基因沉默，细胞异常增生，导致肿瘤的发生[5]。

In order to find highly active pesticide, three series of 5--12-substituent-benzo phenanthridine derivatives were synthesized through the reaction of 2-methylbenzonitrile with dif-ferent aldehyde, and further dehydration with DDQ or N-methylation with NaH and CH3I, respectively.

为了寻找新的高活性农药，利用2-甲基苯甲腈与不同的醛反应，再通过2，3-二氯－5，6-二氰基－1，4-苯醌脱氢或NaH和CH3I氮甲基化，合成了3个系列共18个5-取代氨基－12-取代苯并菲啶衍生物，其中15个是未见文献报道的化合物。

The specific inhibitor of DNA methylation that is available currently is 5-Aza-2'-deoxycytidine (5Aza-dc), which forms a covalent bond with the DNA methyltransferase, thus, limiting the number of free DMT molecules for methylating DNA and then decreasing its biology activity.

目前研究较多的甲基化抑制剂是胞苷类似物5-氮杂-2'-脱氧胞苷(5-Aza-2'-deoxycytidine， 5Aza-dc)。5Aza-dc的作用机制是与DNA甲基转移酶共价结合，降低酶的生物活性。

A DNA demethylating agent. This finding suggests that Met induce the flowering of detached cotyledon culture perhaps through acting as a methyl donor of DNA methylating not as the precursor of ethylene synthesis.

上述结果说明：10^(-5)M Met浸种3 h能显著促进子叶培养物的花芽形成，Met对离体子叶成花的诱导作用可能是作为甲基供体通过DNA甲基化途径来实现的。

The shorter variant mHemk2 is 1696 bp in length encoding a putative mouse protein of 14.7 kDa, consisting of 138 amino acid residues.In protein data bank annotations, Hemk has previously been classed among methyltransferases methylating N6-adenine or N4-cytidine in DNA because of the presence of S-adenosyl-L-methionine binding motif and of an NPPY motif in the protein.

在蛋白数据库的注释中，由于在Hemk蛋白中存在S-腺苷-L-甲硫氨酸结合基序和一个NPPY基序，因此，在蛋白库的说明中已经将Hemk蛋白归类于能甲基化DNA中N6-腺嘌呤或N4-胞嘧啶的甲基转移酶。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。