甲基化的

Vitamin E, or tocopherol, is a lipid-soluble antioxidant and essential for human health. 2-methyl-6-phytyl-1, 4-benzo- quinol methyltransferase, one of the key enzymes in vitamin biosynthetic pathway in plants, converts 2-methyl- 6-phytyl-1,4-benzoquinol to 2,3-dimethyl-6-phytyl-1,4-benzoquinol.

维生素E是一类人体必需的脂溶性抗氧化剂，具有重要的生理功能。2-甲基-6-叶绿基-1，4-苯醌甲基转移酶是天然维生素E合成途径中的关键酶之一，催化MPBQ甲基化，生成DMPBQ。

The results indicate that it is possible to identify and distinguish these siccative oils because the unsaturated acid had changed into azelaic due to oxidation and polymerization during the drying process to make the chromatogram of siccative oils have a typical peak of C9 compound and provide a finger marker of m/z 217, and the concentration ratio of palmitic acid to stearic acid remains constant with time to facilitate the differentiation of oils.

分析时采用了热裂解与甲基化同时进行的技术。分析结果显示，4种干性油的不饱和脂肪酸在成膜后的甲基化产物均为壬二酸二甲酯，离子质量与离子电荷量比值为217，是干性油的特征检测峰。4种油中不同含量的软脂酸和硬脂酸在干性油成膜前后的比值不变，为干性油的甄别提供了可能性。

Chiral centers of C5 and C8 are directly constructed in the key step of the diastereoselective propargylation from D--tartrate. The methylation and subsequent methoxycarbonylation result in desymmetrization of the terminal dialkynes. The α,β-unsaturated δ-lactone is synthesized after partial hydrogenation and lactonization.

由非天然酒石酸出发，利用双向非对映选择性的炔丙基化反应，在一步反应中同时构建C5和C8手性中心；然后通过末端炔基的甲基化、甲酯基化，延长碳链并对分子去对称化；内酯化得到关键中间体α，β-不饱和六元内酯，再经多步反应转化得到8-epi--Boronolide。

Inhibiting gene abnomal methylic P16 become higher with cervical neoplasia,it is a early event in the process of cervical cancer.So it has important clinical significance in early diagnosis of cervical cancer.

抑癌基因P16异常甲基化随宫颈瘤样病变的加重而阳性率增高，P16异常甲基化是宫颈发生的过程中的早期事件，对于宫颈癌的早期诊断具有重要意义。

On the basis of these principles and requirements,in this paper,a new modifier has been synthesized from pyromellitic dianhydride and thiosemicarbazide by the nucleophilic addition of anhydride,the cyclization of acyl thiosemicarbazide in alkaline solution,and the N-hydroxymethylation of the triazole-thione.

本文根据这一思路，以均苯四甲酸二酐和氨基硫脲为起始原料，通过酸酐的亲核加成反应、酰氨基硫脲的碱性环化反应、三唑硫酮环的N-羟甲基化反应合成出了一种新的N-羟甲基三唑硫酮酸改性剂。

The influence of the factors concerning temperature, reaction time, the kind and amount of catalyst, the amount of transmethylation agent and the amount of solvent on the yield of 2,6-DMN was investigated, and the conditions of synthesizing 2,6-DMN based on the transmethylation method were explored.

通过考察温度、反应时间、催化剂的种类及用量、转移甲基化试剂的用量、溶剂用量等因素时2，6-DMN收率的影响，探讨了转移甲基化法合成2，6-DMN的工艺条件。

DNA methylation is essential for silencing transposable elements and some genes in higher eukaryotes, which suggests that this modification must be tightly controlled.

DNA甲基化对于沉默的转座因子和真核细胞的某些基因是必不可少的，这表示DNA甲基化这一过程必须受到严格的控制。

It was found that zymosterol in S. cerevisiae GL7 cells and cycloartenol in P. wickerhamii cells were accumulated when treated with solasodine. Zymosterol and cycloartenol are respective substrates of sterol 24Cmethyltransferase in S. cerevisiae GL7 and P. wickerhamii, hence we deduced that sterol C-24-methyltransferase is the main target of solasodine.

根据澳洲茄胺对S.cerevisiae GL7和P.wickerhamii的甾醇生物合成途径的抑制结果均积累24位甾醇甲基化转移酶的底物，分别是zymosterol和cycloartenol，初步阐明了澳洲茄胺的主要作用靶点是24位甾醇甲基化转移酶，而其它几种抗真菌生药活性成分不影响甾醇的生物合成途径。

While methylcytosines serve as the fifth base encoding epigenetic information, they are also a dangerous endogenous mutagen due to their intrinsic instability.

中文摘要胞嘧啶的甲基化是遗传物质的一种重要修饰方式，增加了DNA的信息储量。但同时由于甲基化胞嘧啶本身的不稳定，它成为细胞内突变的一个重要来源。

We then used a selection process incorporating microarrays and/or real-time PCR analysis of tissue samples to further test marker candidates for maximum methylation in CRC tissue and minimum amplification in tissues from both healthy individuals and patients with other diseases.

然后，我们进行进一步的实验，就是利用芯片技术和荧光定量PCR方法发现候选标志物，这种标志物最大可能性的在结直肠癌组织的发生甲基化，而最小可能的在健康人和其他疾病时发生甲基化。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。