甲基化的

Methods Using a modified semi-nested methylation-specific PCR, the status of methylation of the p16 was investigated in bronchia rinse and whole blood DNA from 26 lung cancer patients.

方法利用半巢式甲基化特异性PCR技术，检测26例肺癌患者支气管灌洗液及相应全血中DNAp16基因的异常甲基化状态。

Methylation assay showed that these sequences are heavily methylated in the Fritillaria ussuriensis.Maxim genome.

甲基化分析则表明这些序列在平贝母的基因组中均被高度甲基化。

Objectives To detect the methylation of P15(superscript INK4B) gene in patients with myelodysplastic syndromes and to investigate the demethylating effects of decitabine and arsenic trioxide (As2O3). Methods The bone marron mononuclear cells from 14 MDS patients were collected.

目的 检测骨髓增生异常综合征患者P15(上标 INK4B)基因甲基化状况；探讨5-氮杂－2'-脱氧胞嘧啶和三氧化二砷(As2O3)对MDS患者细胞的去甲基化作用。

The titled compound as an intermediate for preparing muscone is obtained by reacting a tetradecanedioic acid as the starting material with a chlorinating agent——chlorosulfoxide,followed by reacting the resultant reaction product on halogenomethylzinc .

采用直链十四碳二元酸为起始原料，先以氯化亚砜进行酰化，所得酰氯直接与甲基锌试剂反应进行甲基化，从而制得了合成麝香酮的重要中间体2，15-十六烷二酮，产物结构经1HNMRI、R确认。

Results: No methylation was found at 5'CpG island of exon 1 of p16 gene in normal tissue specimens whereas hypermethylation was found in 3 specimens of rhabdomyosarcoma.

结果： 对照7例p16基因第1外显子5'CpG岛3个酶切位点无甲基化， 3例肉瘤组织中存在这3个酶切位点的甲基化现象。

In the mutant plant,a genecalled Lcyc is extensively methylated and thus not expressed--and thismethylated state is heritable by subsequent generations of toadflax plants.

在突变体植物中，一个叫Lcyc基因广泛甲基化，因此不能表达。这一甲基化状态在云兰属植物中是能遗传的。

The DNA methylation level in stem apices treated with 5-azaC was comparable to that of seedlings treated at 5℃ for 10 days.

本文研究了去甲基化因子5-氮杂胞苷(5-azaC)对萝卜开花及幼苗茎尖DNA甲基化水平的影响。

Methods PCR-SSCP and PCR product cloning, sequencing were performed to detect mutation of p16 gene exon 2 in peripheral blood of 60 patients with arseniasis caused by coal-burning pollution,at the same time,PCR-based methylation assay was performed to analyze the methylation of p16 gene exon 1. Results No p16 gene exon 2 mutation was found in 60 cases.

采用聚合酶链反应-单链构象多态性分析和PCR产物克隆测序技术对60例砷中毒患者外周血中p16基因第2外显子突变情况进行检测，同时采用甲基化敏感的限制性内切酶方法对p16基因第1外显子甲基化情况进行分析。

The improved preparation method for carboxy methylation of konjac glucomannan was proposed in this paper according to molecular structural characteristics of KGM.

针对魔芋葡甘聚糖分子结构特性进行羧甲基化方法的改进，在乙醇介质中先混合醚化试剂，再进行碱化催化反应制备羧甲基魔芋葡甘聚糖。

In the second part of the study, it was speculated that E2 might exert a similar demethylation effect on MGMT hypermethylation to restore MGMT transcription.

本研究的第二部分在探讨雌性素是否会如参与 ER 去甲基化一样造成MGMT去甲基化？

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。