甲基化作用

In addition, hypermethylation at a region next to such a critical region might indicate an early signal of carcinogenesis.

另外，紧靠这些临界区域的超甲基化可能暗示致癌作用的早期信号。

Methylation of histone H3 at lysine 9 has a well-established role in heterochromatin formation and gene transcription regulation.

研究表明，组蛋白H3K9甲基化在异染色质形成及基因转录调控中具有重要的作用。

The changes of epigenetics such as DNA methylation and histone modification can regulate the expression of genes and play an important role in the development of tumors.

表遗传学改变，如DNA甲基化和组蛋白修饰改变可以调节基因的表达，在肿瘤的发生和发展中可能起关键作用。

This article summarized the development of molecular mechanism and application of DNA methylating inhibitor in plants.

本文综述了DNA甲基化抑制剂作用机理及其在植物发育生物学研究中的应用。

In conclusion,this research has gotten some significant results:firstly Kail gene is highly related with the metastasis potential of colorectal carcinoma cells,secondly mutation of Kail gene,methylation of CpG islands in the promoter and abnormal expression of p53 have no important effects in the down-regulation of Kail gene.

本研究结果表明：Kai1基因与大肠癌细胞转移潜能有关；基因点突变、启动子CpG岛甲基化与p53异常在Kai1基因表达下调中不起重要作用。

Objective: With umbilic blood from the mature newborns, to screen CpG-ODN, which can markly boost up the immunity response, from some designed CpG-ODNs; to compare the effect of CpG-ODN on the lymphopoiesis of umbilic blood from the premature, mature newborns and the peripheral blood from the adults; to observe the infulence of CpG-ODN on the immune function of the pregnant mices and their newborns, the immune-inhibited and aged mices.

目的：设计含非甲基化胞嘧啶和鸟嘌呤的寡聚脱氧核糖核苷酸，以期用足月新生儿脐血筛选出具有较强免疫增强作用的CpG-ODN；比较CpG-ODN对新生儿脐血和成人外周血单个核细胞的增殖效应；观察CpG-ODN对孕鼠及其新生鼠、免疫抑制鼠和老年鼠体液免疫功能的影响。

DNA methylation is an important modifiable manner of epigenetic dominating the correct expression of gene. It is a main instrument of regulating genome function and plays a prominent part in the embryonic normal development.

DNA 甲基化是支配基因正常表达的一种重要的表观遗传修饰方式，是调节基因组功能的重要手段，在胚胎的正常发育过程中具有显著作用。

DNA methylation plays an important role in the process of development and gene expression.

DNA甲基化在生物的基因表达调控与发育调节过程中具有重要作用。

DNA methylation that was a kind of modification of DNA had played an important role in the regulation of genes.

DNA甲基化是DNA的一种重要修饰，在基因的表达调控中起了重要作用。

In addition, SOCS-1 methylation may be associated with the initiation and development of pancreatic ductal carcinoma.

SOCS-1基因CpG岛甲基化在胰腺癌的发生、发展中可能具有一定的作用。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。