甲基化作用

Post-translational modification of proteins which contains phosphorylation, acetylation and methylation has attracted more and more attention because of its important role in organism.

蛋白翻译后修饰如磷酸化、乙酰化和甲基化等在生命活动过程中发挥的重要作用使其成为近年来的研究热点。

Protein deamidation is one of the post-translational modifications which also include phosphorylation, methylation and acetylation.

蛋白质的去胺基化是属於后转译的修饰作用，其中还包括磷酸化、甲基化及乙醯化。

The two—step sulfomethy lation and the reaction with HOCH〓SO〓Na in sulfite cooking were illustrated in this paper. The optimum technological conditions were determined on the basis of suitable amount of HCHO in sulfite pulping. The differences of delignification and paper properties of wheat straw were also studied in SFP—AQ and alkaline sulfite and AQ cooking .

对麦草粉的两步法磺甲基化反应以及与羟甲基磺酸钠的反应进行了研究，解释了甲醛在亚硫酸盐蒸煮中脱木素作用机理，从理论上确定了甲醛在SFP—AQ蒸煮中的适宜用量，并据此提出了合理的蒸煮工艺和最佳工艺条件。

Methyle β cyclodextrin was simply synthesized, and the impacts on the solubilization of methyl parathion and carbofuran were investigated.

摘 要：研究了甲基化β环糊精的一种简单制备方法及其对甲基对硫磷和呋喃丹的增溶作用。

The bacterial, mammalian and plant cytochrome P450s involved in metabolism of herbicides are reviewed in this paper. The action modes of cytochrome P450s on herbicides including dealkylation, ring-methyl hydroxylation and aromatic ring hydroxylation etc are summarized.

本文综述了代谢除草剂的细菌、哺乳动物和植物细胞色素P450酶系，概述了细胞色素P450酶系参与除草剂代谢的作用方式：脱烷基化作用、环甲基化羟基化作用和芳环的羟基化作用等。

ResultsThe rate of methylation of p15 gene was detected 37.8% in the tumor tissues and naive in the normal uro...

结论p15基因在膀胱移行细胞癌组织中的甲基化率较高，其异常高甲基化在膀胱癌的发生、发展中具有重要作用。

It was found that zymosterol in S. cerevisiae GL7 cells and cycloartenol in P. wickerhamii cells were accumulated when treated with solasodine. Zymosterol and cycloartenol are respective substrates of sterol 24Cmethyltransferase in S. cerevisiae GL7 and P. wickerhamii, hence we deduced that sterol C-24-methyltransferase is the main target of solasodine.

根据澳洲茄胺对S.cerevisiae GL7和P.wickerhamii的甾醇生物合成途径的抑制结果均积累24位甾醇甲基化转移酶的底物，分别是zymosterol和cycloartenol，初步阐明了澳洲茄胺的主要作用靶点是24位甾醇甲基化转移酶，而其它几种抗真菌生药活性成分不影响甾醇的生物合成途径。

cDNA microarray was an effective and useful method to survey gene expression profiles in pancreatic carcinoma. MBD1、EDG1 and its hyper methylating modulation may play an important role in the pathogenesis of pancreatic cancer, among which the high expression of MBD1 in pancreatic cancer would be the key modulating point in the down regulation of multiple methylation related suppression genes transcription.

cDNA微列阵技术为胰腺癌相关基因表达谱的分析提供了有力的工具，MBD1、EDG1等基因过甲基化表达调控可能在胰腺癌发病机制中起着关键作用，而MBD1在胰腺癌中高表达可能是多个甲基化相关抑癌基因转录表达下降的关键调控点。

MBD1、EDG1 and its hyper methylating modulation may play an important role in the pathogenesis of pancreatic cancer,among which the high expression of MBD1 in pancreatic cancer would be the key modulating point in the down regulation of multiple methylation related suppression genes transcription.

cDNA 微列阵技术为胰腺癌相关基因表达谱的分析提供了有力的工具，MBD1、EDG1等基因过甲基化表达调控可能在胰腺癌发病机制中起着关键作用，而MBD1在胰腺癌中高表达可能是多个甲基化相关抑癌基因转录表达下降的关键调控点。

MCA coupled with RDA is an effective technique to screen the differentially methylated sequences between MACC and normal colonic tissue.

运用MCA结合RDA分析可以有效分离结肠癌癌旁粘膜与正常结肠组织的差异甲基化DNA片段，为肿瘤等疾病的表遗传研究如DNA甲基化的作用、新抑癌基因的发现提供一个很好的研究方法。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。