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The pharmacological profile of HupA is similar to that of tacrine, including the inhibition of AChE, the antagonism to the NMDA receptor, and the neuroprotection in vitro.

目前,石杉碱对离子通道的作用还知之甚少,因此本论文将着重研究石杉碱对脑内电压门控通道的作用,并探讨其可能的作用机制。

Secretion of sAPPα and expression of PKCα were found to increase after cells were incubated with HupA, suggesting a possible correlation between these two changes.

Western blotting结果显示sAPPα和PKCα蛋白水平均随着与石杉碱孵育的时间增加而增高。sAPPα的显著上升出现于PKCα上升之前,提示石杉碱对sAPPα分泌的调节可能与提高PKCα表达水平有关。

Increases of APP transcript and expression by HupA also contribute to the up-regulation of sAPPα secretion. Meanwhile, Aβ secretion was observed to decrease 2 h after HupA treatment, and after 24 h incubation, HupA can significantly inhibit the secretion of Aβ.

Real-time PCR和Western blotting结果提示石杉碱能增加APP的转录和表达,该作用也将有助于对sAPPα分泌的上调;同时Aβ的生成并未相应增加,ELISA检测结果显示石杉碱孵育2 h后即能对Aβ分泌产生抑制作用,孵育24 h后能显著降低Aβ水平。

According to the contrasts between the structure of PANI and that of POT, the conclusion could be made that steric hinderance effect of methyl groups in the poly-O-methylaniline is more prominent than induction effect and hyperconjugation.

比较聚苯胺和聚邻苯胺的结构可知,基取代苯环中的一个氢原子后,基对聚邻苯胺的空间位阻效应明显大于诱导效应和超共轭效应。

The synthesis process comprises using chiral phosphorus acid as catalysis, synthesizing 2-(4, 7-indoline) compound in high efficiency and highly enantioselective by using sulfur imide and 4, 7-indoline compound, and products can be used to prepare several 2-dimethylamino indoline compounds with high optical activity through oxidation reaction.

以手性磷酸作为催化剂,由磺酰亚胺和4,7-二氢吲哚化合物可以高效率高对映选择性的合成2-氨基(4,7-二氢吲哚)化合物;产物可以经过氧化反应用于制备多种高光学活性的2-氨基吲哚化合化合物。

An ion-pair HPLC method for determination of metronidazole and vitamin B_6 in compound metronidazole tablets was establish.

建立了同时测定复方硝唑片中硝唑和维生素B6含量的离子对HPLC方法。

A novel ionic liquid Caprolactam-trifluoromethanesulfonic acid was prepared with trifluoromethanesulfonic acid and Caprolactam as raw material. The structure of the ionic liquid was characterized by 1HNMR and FTIR.

以三氟磺酸和己内酰胺为原料制备了一种新型离子液体己内酰胺三氟磺酸,用1HNMR、FTIR对其结构进行了表征。

And each Yao have:Prosperous, Inferior prosperity, rest, jailbird, die 5 kinds of appearances,each 6 Yao Guas having a 36 multiply by 5= is 180 kinds of appearances.but 64 Guas became the Gua of the 64 X36 X5=11520 different types and appearance.if 60 cycle of sixty years day, bring into 360 cycle of sixty yearses day frame for a year,The circumstance will take place important variety!

再加上每一爻有:旺,相、休、囚、5种状态,每个6爻卦就有36X5=180种状态。而64卦就变成了64X36X5=11520个不同类型和状态的卦。如果将60子日纳入到一年的360子日构架之下,情况将会发生重大的变化!

No I do not think it would be very good to penetrate a chained mail, the I would rather user one like on the Thread: An armour piercing katar .

不,我并不以为它善于刺穿锁子,我觉得用"主题:穿的卡塔尔"会更好些。

No I don't think it would be very good to penetrate a chained mail, the I would rather user one like on the Thread: An armour piercing katar .

不,我并不以为它善于刺穿锁子,我觉得用"主题:穿的卡塔尔"会更好些。

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Do you know, i need you to come back

你知道吗,我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书,王祥生,李德昌。安徽省首次发现嗜群血蜱。

Chapter Three: Type classification of DE structure in Sino-Tibetan languages.

第三章汉藏语&的&字结构的类型划分。