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AIM: To isolate bioactive secondary metabolites from the fruits of Schisandra rebriflora Rehd. et. Wils and study their effects on HIV-1 infectivity. METHODS: Inhibition of syncytia formation, HIV-1 reverse transcriptase and protease, protection of HIV-1 infected cells, level of HIV-1 p24 antigen,blockage of fusion were detected. RESULTS: A lignan compound, named rubrifloralignan A, was first isolated as a natural product with modest inhibition effects on syncytium formation and HIV- 1 replication and could protect HIV-1 infected cells with weak inhibition effects on fusion and RT, but it showed no effects on the replication of HIV-1 chronic H9 and PR. CONCLUSION: Rubrifloralignan A is an efficient anti-HIV-1 product with effect on early stage of HIV-1 replication.

目的:从红花五味子果实中寻找活性代谢产物,研究其抗HIV—1活性和作用机制方法:通过合胞体抑制、HIV-1感染细胞保护、HIV—1p24抗原测定、融合阻断、逆转录酶和蛋白酶活性分析等实验,检测分离化合物的抗HIV—1活性并探讨其作用机制一结果:红花五味子素能够抑制病毒诱导的合胞体形成,保护病毒感染细胞,抑制病毒在细胞内的复制对HIV-1感染细胞与正常CD4^+细胞间的融合,逆转录酶活性有一定的抑制作用但是红花五味子素不抑制病毒在慢性感染细胞中的复制,也不抑制蛋白酶的活性、结论:首次从天然产物中分离得到红花五味子素,它对HIV—1病毒复制早期具有抑制作用

We know that at Thermopylae few of the Spartans were equipped with linothorax but not with metal breastplates.

我们知道在温泉关的时候只有极极少数的人装备了 linothorax (布料和动物皮制成的复合)但是没有一件金属的铜胸

Results show that, by using thionyl chloride and N,N-dimethyl formamide as chlorinating reagent and dichloromethane as solvent and taking -15℃ as reaction temperature, Z-iomer crystals with pale white color and stable to temperature can be obtained with an overall yield of 70%.

以2-(2-氨基噻唑-4-基)-2-氧亚氨基乙酸为原料,经盐酸化、氯代等反应合成了Z-2-(2-氨基噻唑-4-基)-2-氧亚氨基乙酰氯盐酸盐;氯代时以用亚硫酰氯和N,N-二酰胺的混合物代替五氯化磷作氯化剂,并考察了温度和溶剂对氯代产物中Z-异构体和E-异构体收率的影响。

The hearts were extracted from rats and set up as acute hibernation models.The spontaneous and stimulationevoked releases of myocardial noradrenalin during acute hibernation were determined by using a highperformance liquid chromatography method,the effect of desipramine and tyramine on release of myocardial noradrenalin was also evaluated.

用高效液相色谱法测定急性心肌冬眠时心脏去肾上腺素的自发性和电场刺激引起的释放,并评价去丙咪嗪和酪胺对去肾上腺素释放的影响及酪胺对心率的影响。

And Arhopalus unicolor could beserved as the substitute host instead of the Monochamus alternatus Hope for thepropogation of Dastarcus helophoroides indoors.

其中松褐天牛幼虫和蛹是花绒坚的最好自然寄主,黄粉是花绒坚相对较适合的替代寄主,有关人工食料饲育研究有待进一步深入。

Methoxystilbene and 2-methoxy-4'-nitrostilbene were synthesized from benzyl chloride and nitrobenzyl chloride by the Wittig reaction, and used as intermediates for the synthesis of the final product fluorescent whitener FP4,4'-bis(2-methoxystyrylbiphenyl via reduction and diazotisation of the latter followed by reaction with the former in the presence of NaOH.

以氯化苄和对硝基氯苄为原料,经Wittig反应合成中间体:2-氧基-二苯乙烯和2-氧基-4'-硝基-二苯乙烯。后者经还原反应、重氮化反应后,在氢氧化钠存在下与前者反应生成最终产品荧光增白剂FP4,4'-双-2-(氧基苯乙烯基联苯。为该类荧光增白剂的合成开辟了一条新路线

Similar to S-adenosylmethionine decarboxylase(B26),S-adenosylmethionine methyl-transferase(B70), allene oxide synthase(B38),ethylene receptor(B96),cytochrome P450(B58) and methionine synthase (B77) were found in ovaries of Pingyi Tiancha at 1d before the blossom day,which related to plant hormone and could participate in metabolic pathways of ethylene,polyamine,jasmonate acid and gibberellin,et al.,as well as had close relationship with maturity and senescence of plants.

在平邑甜茶开花前1d的子房中发现的S-腺苷硫氨酸脱羧酶(B26)、S-腺苷硫氨酸基转移酶(B70)、丙二烯氧化合酶(B38)、乙烯受体(B96)、细胞色素P450酶(B58)、硫氨酸合酶(B77)等相似基因片段与植物体内的生长素有关,将会参与乙烯、多胺、茉莉酸、赤霉素等的代谢途径,与植物的成熟和衰老具有密切的关系。

We have not found any reports that o-toluidine and N,N-dimethylaniline can be used as antiknock. The electrochemical properties of aromatic amine are in line with its' antidetonating quality and actual application.

而实际上采用胺类化合物作抗爆剂时,一般使用N-基苯胺、苯胺、邻苯胺及间苯胺,尚未见到使用对苯胺和N,N-二基苯胺的报道。

Computationalresults indicate that the no-planar trans-benzanilide is the most stable structure. The spectra indicate that the Franck Condon region photodissociation dynamics have multidimensional character withnine activemodes. The intensity of υ24 mode in methanol is much stronger than that in acetonitrile. Compared with fatty amides and benzamide, phenyl substitution for H atom on-NH2 group makes C=O solvent effects disappear.

结果表明,苯酰苯胺的非平面反式结构为最稳定结构;在Frank-Condon区域内,苯酰苯胺主要由9个活性振动模组成;其中ν24(苯环上C=C不对称伸缩振动和CCH的面内弯曲振动,NH面内弯曲振动)振动模在醇溶剂中的强度远远大于其在乙腈的强度;与脂肪酰胺类化合物和苯酰胺的研究结果比较发现,苯基取代-NH2上的H原子使得C=O不再具有明显的溶剂效应。

A three-dimensional large pore zeolite Hβ is used in the benzoylation of anisole instead of the classical Lewis acid catalysts to synthesize the important fine chemical intermediate 4-methoxybenzophenone.

采用高硅铝比、热稳定性好的三维大孔Hβ沸石替代传统Lewis酸催化剂催化苯醚的苯酰化反应,合成了重要精细化工中间体4-氧基二苯酮,收率可达92%。

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推荐网络例句

I can not make it blossom and suits me

我不能让树为我开花

When temperatures are above approximately 80 °C discolouration of the raceways or rolling elements is a frequent feature.

当温度高于 80 °C 左右时,滚道或滚动元件褪色是很常见的特征。

The lawyer's case blew up because he had no proof.

律师的辩护失败,因为他没有证据。