生物芯片

This research is helpful for the development of microarray research and application and it amplify the content of bioinformatics.

该领域的研究促进了基因芯片的研究与应用，丰富了生物信息学的研究内容。

Projects included: Cloning and functional studies of diabetes related genes;Structural studies of thermostable Catechol 2,3-Dioxygenase by anomalous scattering; Prevention and cure, and influence factor studies of major child bearing blemish of national minority in Guizhou province.

该课题组的主要研究方向包括大规模高通量人类基因克隆及功能研究；基因芯片技术、生物信息学及功能基因组学研究；蛋白质晶体结构与功能；蛋白质热稳定机制；疾病相关基因的研究。

The electronic and spraying biochip is a new biochip, it is used for analyzing pharmacologic variability by linking mass spectrograph, the micro-nozzle is key part.

生物电喷芯片是和质谱仪连用，用于药理分析的一种新型芯片，其中微喷嘴是制备的关键。

To this end,we used the Transwell system to select two highly invasive subcell lines SNU5-P3 and PAMC82-P3 from minimally invasive parent cells,and compared gene expression in paired cell lines wit...h high and low invasive potentials.38 genes were commonly upregulated in the two highly invasive subcell lines.

通过全基因组芯片比较SNU5-P3和PAMC82-P3与其亲本细胞的基因表达谱，获得了38个在两张芯片共同上调表达的差异基因，其中16/38(42%)已报道是与侵袭转移功能相关的基因。LOXL2是一个在两张芯片共同上调表达的基因，通过生物信息学分析和细胞表达谱分析，表明LOXL2可能是胃癌侵袭转移密切相关的功能基因。

As MEMS (Micro Electro-Mechanical Systems) technology progresses rapidly, the synergism between MEMS and biomedical technology becomes closer than ever before. When the uTAS was introduced in the last two decades, many microfluidic chips, microelectrodes, and microreactors are being studied for drug detection, environment detection, gene analysis etc. Due to its small volume, low pollution, low consumable and good portability, uTAS plays a very important role in biomedical, biochemical, environment engineering fields.

随着MEMS(Micro Electro-Mechanical System，微机电系统)制造技术的不断发展，生物医学与其之间的联系越来越紧密，自上世纪90年代初提出uTAS(Micro Total Analysis System，微全分析系统)之后，各种各样的微流控芯片、微反应器、微电极、微分离器等便大量涌现，广泛应用于药物检测、环境监测、基因分析等诸多领域中，并且由于其试剂消耗量少、检测效率高、环境污染小、体积小、易于携带等优点，在生物医学、化学、环境工程等领域受到越来越多的重视。

It combines microelectric technique with molecular biology, erects a bridge between the life sciences and the information science, which is the most important technology of the gen

基因在芯片的研制在我国也已起步并取得了重要的进展。我国已经在少数民族基因组的保存、致病基因的分离、生物信息学以及基因组新技术开发等方面取得了良好的开端，但达到临床应用的水平还不是很高。本文主要就基因芯片原始图像用计算机图像分析

The possibility of researching gene mutation with the technique of gene chip was discussed. A new imagination to randomly determine DNA sequence in different living beings with the technique of gene chip was advanced. In this way, whether the encoding sequence gene in DNA of eukaryon organism has some regularity was studied.

进而提出新设想——采用基因芯片技术对不同生物群体随机抽样进行DNA测序，从而探讨在真核生物DNA分子链上编码序列遗传基因的变化是否有规则而非随机的，非编码序列遗传基因是否为生物进化过程中曾经有表达能力的结构基因，并分析可能获得的结果。

ANALOGIES are often drawn between the fields of computer science and biology. The information-processing abilities of DNA are a form of natural molecular computing, and computer viruses leap from machine to machine in ways reminiscent of their disease-causing namesakes. At the International Solid-State Circuits Conference in San Francisco this week, a trio of mighty information-technology firms—Sony, Toshiba and IBM—pushed the analogy a little further. They unveiled a much anticipated new computer chip, four years in the making, the very name of which is a biological metaphor: the Cell.

人们经常把计算机科学和生物学进行类比，DNA的信息处理能力是一种自然分子的计算形式，而计算机病毒则让人想起致病性生物病毒，从一台机子感染另一台机子，而这个星期，信息技术的三巨头——索尼、东芝和IBM在旧金山召开的国际晶体管集成电路会议上，把两者间的这种类比作了进一步的推进，他们披露了一种已经研制了四年的、非常有希望的新型计算机芯片，这种芯片的名字来自生物学：细胞。

Computers have so far been based on two-dimensional chips made from silicon, but there are developments already well advanced to make three-dimensional chips with vastly improved performances, and even to construct them out of biological molecules that can be miniaturised even more than metal-based computer chips.

目前，二维芯片主要用硅制造，现在已经开发了更先进，能量更大的三维芯片，甚至能够用生物分子制造比金属芯片体积更小芯片。

Genechip is the cross-link between biotechnology and microelectronical technology, which has the advantage of high efficiency.

基因芯片作为生物技术与微电子芯片技术融合的结晶，具有信息量大、效率高的优点，可以实现对基因数据的大规模检测。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。