生物素

Biochemistry ; daidzein ; phospholipid ; phospholipid complex ; action spectrum analysis ; antioxidant ; immune function ; cellular metabolism

生物化学；大豆黄素；大豆卵磷脂；磷脂复合物；光谱分析；抗氧化；免疫机能；细胞代谢

Currently activities involve (1) Investigation of dye-DNA interaction by using spectroscopic methods to probe the binding sites between chromophore and DNA and to identify various DNA conformational structures, particularly the telomeric DNA;(2) Investigation of the structure-activity correlation of anti-telomerase agents;(3) Design and synthesis new compounds for antitumor agents and fluorescence biomarkers;(4) Monitoring the folding and unfolding of quadruplex structure, tracing the pathway of drug delivery and probing drug-target interaction by using single molecule microscopy and spectroscopy.

目前 的研究重点分别是(1)利用光谱方法探讨探针分子与DNA的交互作用，特别是作用位置与结构变化；(2)研究抗端粒酵素作用分子之结构与生物活性之关系；(3)设计及合成抗肿瘤药剂或萤光生物标记；(4)建立单分子萤光光谱与影像技术，研究 DNA的多变型结构之变化机制，监测药物输送的路径过程及其在细胞中与标的物的作用。

The rules of photo bioactivities are: Without illumination, the tested xanthene derivatives showed almost the same level of inherent toxicity to the same organism, which showed the inherent toxicity of xanthene derivatives were primarily dependent on the structure of parent molecule. Upon illumination, the photosensitizers showed obvious phototoxicity to all organisms. The xanthene derivatives showed stronger phototoxicity to Gram-positive bacteria. With the increasing number of halogen substituents, the singlet oxygen yields increased and the phototoxic activity increased too.

呫吨类化合物的生物活性的变化规律为：未经光照的条件下，呫吨类化合物的对同种待测微生物的固有生物活性基本相同，说明固有毒性可能主要决定于化合物分子的母核结构，其卤素取代基团对其影响较小；经实验光源照射下，所测MLC值明显低于未经光照条件下的值，表明呫吨类化合物对三种微生物的光敏活性明显强于对其相应的固有活性；呫吨类化合物对革兰氏阳性菌能发挥较大的光敏活性。

In order to overcome the problem of multidrug resistance in human epidemic carcinomata anti-adriamycin cells (KB-A-1), the antisense and antigene oligonucleotides were used to investigate their effectiveness on inhibiting the mdr1 gene expression. The effectiveness of antisense or antigene oligonucleotide on inhibiting the multidrug resistance was detected by MTT colometric assay and ELISA.

中文题名反义与反基因寡核苷酸及其萘二酰亚胺偶联物对靶基因表达的抑制作用研究副题名外文题名 The inhibition of the targeted gene expression by the antisense or antigene oligonucleotides and their naphthylimide-conjugated derivatives 论文作者李军生导师张元兴魏东芝教授学科专业生物化工研究领域\研究方向生物化学与分子生物学学位级别博士学位授予单位华东理工大学学位授予日期2001 论文页码总数106页关键词基因表达基因治疗反义寡核苷酸反基因寡核苷酸核酸馆藏号BSLW /2001 /Q78 /264 针对人表皮癌抗阿霉素细胞株（KB-A-1）的多药抗药性问题，本文从反义核酸和反基因核酸角度，通过MTT法检测细胞生长情况，ELISA法检测基因表达产物P-gp表达水平的变化，对寡核苷酸抑制肿瘤细胞MDR1基因表达的机制进行了探讨。

The active ingredient in rennet is chymosin. Chymosin can also be produced by other means, including biotechnology. Chymosin produced using biotechnology is halal.

凝乳酵素中的活性成份是凝乳酶，凝乳酶还可以用包括生物技术的其他方法生产出，使用生物技术生产的凝乳酶是符合Halal 要求的。

B. Antepartum fetal surveillance can include the nonstress test, BPP, oxytocin challenge test, or modified BPP.

B。产前胎儿监护包括无应激试验，生物物理评分，催产素应激试验，或改良的生物物理评分。

This article sums up and analyzes many clinical and experimental study which using biological toxin preparation such as phrynin, scorpion venom, snake venom, bee venom and cantharidin to prevent and cure primary carcinoma of liver, funds out that the biological therapeutics of using toxin to treat disease has good effect in hepatic carcinoma's prevention and cure.

1山东医学高专，2临沂市肝胆病医院山东临沂276002本文通过对生物毒素制剂蟾毒、蝎毒、蛇毒、蜂毒和斑蝥素防治原发性肝癌的临床和实验研究资料进行总结和分析，发现&以毒攻毒&生物疗法对防治肝癌有较好效果。

Cells from the resulting soup were placed in a biodegradable polymer scaffolding and implanted in the abdomens of immunosuppressed rats, close to blood-rich tissues.

在美国波士顿的福塞斯研究院，由分子生物学者叶里克领导的研究团队从六个月大的猪嘴中取出尚未长出的臼齿，用酵素加以溶解，再从中取出细胞，置于生物可分解聚合物制成的支架中，植入免疫力遭抑制的大鼠腹内、近血管分布密集的部位。

Would like to mention biological carcinogens, inevitably referred to aflatoxin, which is known to cause cancer is the most poisonous biological macromolecules.

要提到生物致癌物质，必然提到黄曲霉素，它是知道的最毒的致癌生物大分子。

The topics in this lab course include the following areas: Microscope and cell morphology, Cell Physiology, Enzymes, Mitosis and meiosis, Cellular respiration, Photosynthesis, Mendelian genetics, Prokaryotes, Protists, Fungi and lower Plants.

本学期课程包含显微镜介绍、各种动、植物细胞形态及构造、细胞生理现象、酵素反应、细胞有丝及减数分裂、遗传性状、细胞呼吸作用、光合作用、原核生物形态、原生生物形态、真菌形态及苔藓植物形态。

What would he tell Judith and the children?

他将怎样告诉朱迪丝和孩子们呢？

I this is at that time, the opinion with peacockish true girl is full of in a heart.

这就是当时的我，一个心中布满虚荣的女孩子真实的想法。