生物碱类

In this thesis, we developed a new method to construct 2, 3, 6-trisubstituted piperidines using enantiopure -amino acid derivatives as the starting material and applied them to the synthesis of some piperidine alkaloids which showed interesting physiological activities.

本论文中，我们从非手性原料出发，通过手性胺对、(-不饱和酯的Michael加成来获得光学纯的-氨基酸酯，发展了一种构建2、3、6-三取代哌啶环的方法，并利用这种方法合成了一些具有重要生理活性的生物碱类天然产物。

Analysis of spectral data for 13CNMR of sixteen strychnos alkaloids.

马钱子中16个生物碱类化合物13CNMR谱的数据分析。

Commonly used alkaloidal salts may be titrated accurately with acetous HClO_4 in non-aquous media in semi-micro scale using crystal violet as visual indi- cator.

作者对常用的生物碱类药物及其注射剂片剂，试用半微量非水溶液滴定法进行测定其含量。

Aim To study the relationship between permeability coefficient and oil/water partition coefficient of 17 alkaloidal drugs.

目的研究生物碱类药物经皮吸收系数与药物油/水分配系数的关系。

Results The relationship between permeability coefficient and oil/water partition coefficient of 17 alkaloidal drugs or drugs containing 2%Azone can be described as following equations.logkp=7.35×10-2-3.079×10-2logk-8.112;logkp(2%Azo)=8.32×10-2-2.68×10-2logk-5.272,respectively.

结果生物碱类药物的经皮渗透系数与药物油/水分配系数的关系式为：logkp=7.35×10-2-3.079×10-2logk-8.112；logkp(2%Azo)=8.32×10-2-2.68×10-2logk-5.272；结论 17种药物的油/水分配系数平均最佳值为2.83，含2%氮酮后的其平均最佳值为3.17。

OBJECTIVE To establish a new TLC method for identification of some active components alkaloids in Rhizoma Arundo donax L.METHODS Rhizoma Arundo donax L.

目的 建立一种可以同时鉴别芦竹根药材中多种生物碱类成分的方法。

RESULTS In the thin-layer chromatogram of Rhizoma Arundo donax L., the spots of the main alkaloids were round, clear, and well separated.

结果 芦竹根药材薄层色谱图中，各主要生物碱类成分斑点圆整、清晰、分离度好。

Establishing experimental animal model of immunized fibrosis could contribute to research on extracellular matri and cytokine. they turns out that the ingredient of Desmodium pulchellum can relieve extra growth and deposit of ECM and adjust the level of relative cytokine, such as TGF-β1 and IFN-γ, benefit to effect of hepatic anti-fibrosis.

结果证明排钱草生物碱类成分能减轻肝纤维化的基本病理改变即减少肝细胞外基质的过度增生和沉积，调节与肝纤维化密切相关的TGF-β1、IFN-γ等细胞因子水平，向着有利于减轻肝纤维化的方向发展。

Objective: To develop an RP-HPLC method for the determination of synephrine in Pericarpium citri reticulatae viride.

目的：建立青皮药材中生物碱类成分辛弗林的含量测定方法。

The invention relates to a new strain producing taxol and a taxol preparation method. The taxol is a diterpenoid alkaloid drug which is extracted from taxaceae plants and has a plurality of anti-tumor effects. Taxus, also known as yew, is a prehistoric plant with a history of 0.2 billion years and is a rare plant species with low growing speed; the biological characteristics of the taxus have high demand on the ecological environment; the natural renewal ability is poor, so the amount of the species is very limited, belonging to an endangered protection plant with limited resource, thus, scientists at home and abroad actively research and develop new taxol sources. The new strain for producing the taxol of the invention is the strain which is first separated from the bark of T.cuspidate Sieb.

产紫杉醇的新菌种及其选育和制备紫杉醇的方法，紫杉醇是从红豆杉属植物中提取出来的具有多种抗肿瘤疗效的二萜生物碱类药物，由于红豆杉，又名紫杉，是两亿年前的史前植物，是珍稀树种，生长速度缓慢，并且其生物学特性对生态环境要求较高，天然更新能力差，所以种群数量极为有限，属濒危保护植物，资源十分有限，因此，国内外学者都在积极地研究开发紫杉醇的新药源，本发明产紫杉醇的新菌种，所述的新菌种为从东北红豆杉T.cuspidate Sieb。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。