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The invention relates to a chirality sensor based on bovine serum albumin and the manufacture method.

不同的手性异构体在生物体内的生物活性,药理作用,代谢过程等有着明显的差别,因此发展简单,准确,快速的手性识别方法成为近年来手性分析的主要方向。

In this thesis, researches have been made on the structure of membrane protein and the process of protein aggregation and disaggregation by employing the two advantages of atomic force microscopy : nanometer resolution in liquids and in situ observation following a biological dynamical process during a long period. This thesis consists of four parts.

本论文利用原子力显微镜能够在溶液中观察生物大分子的结构并可以达到纳米级分辨率和能够在近生理的环境中对生物样品的活性过程进行跟踪观察的两大优势分别对膜蛋白的结构和蛋白质积聚、解聚的过程进行了研究。

At last, HF/4-31G means was used to calculate the model molecules of the 4 complexes, the calculated results revealed the relationships between the bioactivity of Huperzine A analogues and the Mullicken Bonding Populations, Lowest Unoccupied Molecular Orbital energies of HupA analogues.

四个复合物模型分子的量子化学研究结果揭示了化合物的生物活性与复合物中化合物和酶之间的Mullicken键级、活性状态化合物的LUMO轨道能量等量子化学参数之间的联系,初步指出了阳离子-π作用的重要性。

The authers give a brief account of the present situation and prospects for the application of immunochemical methods to agricultural sciences, inculding identification of species, diagnosis of animal and plant diseases, quantitative and locative analysis of substances of biological activity in living things, determinat...

本文介绍了农业科学研究中,在物种鉴定、快速诊断和检疫、生物活性物质的测定、性状标记物和次生代谢物的测定、食品和环境中残毒的检测、生物物质的定位等方面血清学技术的应用现状和前景。

Three electrochemical processes of circulating voltammetry,alternating impedance and differential pulse are adapted to study the synthetic Schiff alkali matcher and its effective mechanism with DNA.Results: The Schiff alkali matcher has a sensitive oxygenated and reduction climax at 0.4 and 0.8 v.

研究具有抗癌活性的小分子与DNA的相互作用,对于认识它们的生物活性、药物作用机制以及高效低毒的新药设计、新药筛选、化疗药物的改型换代具有十分重要的意义[3]。

Producing PHAs,and then were orientationally inserted into a prokaryotic expression vector pBV220. By analyzing the bioactibity and function of their products, the biological function of phaA, phaB and phaC was confirmed. These have been done in our laboratory. To make better use of the three genes by plant bioreactor, two groups of different plant expression vectors that can be used to produce PHAs in different plants were constructed, and the transformation of PHA in Oxalis triangnlaris has been preliminarily reseached.The following is the main results:Three plant expression vectors pBI121-A,pBI121-B and ubquiting-C, which can be used to be transformed into Oxalis triangularis were respectively constructed by using the phaA, phaB and phaC.

菌株的亚克隆基因组片段中,分离出phaA、phaB和phaC三个基因片段,定向克隆至原核表达载体pBV220,通过对其生物活性与功能分析,确证了基因phaA、phaB和phaC的生物学功能;为了通过植物生物反应器对这三个基因进一步研究利用,本实验利用这三个基因构建了两组可用于不同植物生产PHA的真核表达载体,并对紫叶酢浆草进行PHA基因遗传转化的初步研究,获得主要结果如下:利用克隆的phaA、phaB、phaC三个基因分别构建了可用于转化紫叶酢浆草表达载体pBI121-A、pBI121-B、uBquiting-C;可用于玉米转化的种子特异性表达载体p7S-A、pBI121-S-B、uBquiting-C。

Currently activities involve (1) Investigation of dye-DNA interaction by using spectroscopic methods to probe the binding sites between chromophore and DNA and to identify various DNA conformational structures, particularly the telomeric DNA;(2) Investigation of the structure-activity correlation of anti-telomerase agents;(3) Design and synthesis new compounds for antitumor agents and fluorescence biomarkers;(4) Monitoring the folding and unfolding of quadruplex structure, tracing the pathway of drug delivery and probing drug-target interaction by using single molecule microscopy and spectroscopy.

目前 的研究重点分别是(1)利用光谱方法探讨探针分子与DNA的交互作用,特别是作用位置与结构变化;(2)研究抗端粒酵素作用分子之结构与生物活性之关系;(3)设计及合成抗肿瘤药剂或萤光生物标记;(4)建立单分子萤光光谱与影像技术,研究 DNA的多变型结构之变化机制,监测药物输送的路径过程及其在细胞中与标的物的作用。

Then PLGA Micro spheres can promotes the proliferation of osteoblast in a long perlod because of the controlled release of bFGF from microspheres. The PELA microspheres satisfied the proprty reguirement of controlled release, but the biological activity of the released bFGF is partially destroyed.

2体外细胞试验中,游离bFGF对成骨细胞具有促分裂增殖的作用,但效应期很短;而PLGA微球通过持续释放活性bFGF,可在较长时期内促进成骨细胞的分裂增殖;PELA微球虽然达到了缓释的性能要求,但释放出的bFGF的生物活性受到了破坏。

Isolation nematocidal compounds from nematophagous fungal strain K14: It is important to search for metabolites from microbes in controlling nematode because the effect of biotic and abiotic factors of soil to mycelium of microbes is evident.

一株产毒杀线虫菌物活性化合物的分离:由于活体菌对线虫的生防受土壤生物和非生物因素的影响较大,激发人们努力探索微生物次生代谢产物来防治线虫。

The effects of electronic and steric effect of substituted groups, the structure of chiral catalysts and chiral reagents and the reaction system on optical activity of products are summarized.

文章概述了芳香酮取代基的电子效应与空间效应、手性催化剂和手性试剂的结构、反应体系等对产物光学活性的影响,以及全细胞酶、分离酶等不同生物催化体系中芳香酮结构对产物光学活性的影响,并展望了不对称还原的研究及应用前景。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。