生物活性的

On the one hand,Magnetic Polymer Microsphere could covalent active materials—enzymes,cells and antibodies;on the other hand,they could show strong magnetic responsibility for their directional movement in the magnetic field.

一方面磁性聚合物微球可通过共价键来结合酶、细胞和抗体等生物活性物质；另一方面因其具有"在外界磁场存在下能定向运动"这一特殊性能，可对外加磁场表现出强烈的磁响应性，因此它被用作酶、细胞、药物等的载体，广泛地应用到生物医学、细胞学和生物工程等领域。

Taking advantage of the research basis on indole and furan derivatives in our group, a series of 2-substituted 6-benzyloxyindole derivatives was designed and synthesized.

通过初步的体外生物活性试验，测试了所合成化合物对稻瘟霉菌等真菌和细菌的抑制活性，以及对肿瘤细胞株的细胞毒活性。

In order to find active pesticide leading compounds, thinking about that triazolothiadiazoles had various biological activities, this paper designed and synthesized 11 novel title compounds from 3-substituted-4-amino-5-mercapto-1,2,4-triazoles with heterocyclic carboxylic acid via cyclization in the presence of phosphoryl chloride by the princple of combination of active strucural moieties. The structures of the title compounds were characterized by melting point, IR, 1HNMR and elemental analysis.

为了寻找高活性农药先导化合物，考虑到三唑并噻二唑衍生物具有广泛的生物活性，本文利用活性亚结构拼接原理，将活性基团分别引入1，2，4-均三唑并[3，4-b]-1，3，4-噻二唑杂环的3位和6位，合成了未见文献报道的3，6-二取代均三唑并[3，4-b]-1，3，4-噻二唑类化合物11个，并用IR、1HNMR及元素分析测试技术对其进行了结构表征。

Aim at more than 20 kinds of poisonous plants process the identify of biological activity to extract. Results showed: abstract of Ranunculus japonicas Thunb., Pharbitis nil Choisy, Cicuta virose L., Aconitum coreanum Raipares, Aconitum kusnezoffii Reichb.

针对其中的20余种有毒植物进行提取物的生物活性鉴定试验结果表明：毛茛、牵牛子、毒芹、黄花乌头、北乌头几种有毒植物的粗提取物具较高杀螨活性；59种有毒植物提取物中有31种对菜青虫的拒食活性在50%以上。

The preliminary bioassay showed that some title compounds exhibited certain fungicidal activities and cucumber cotyledon root-formation promoting activities.

初步的生物活性测试结果表明，部分化合物具有一定的杀菌活性和促进黄瓜子叶生根活性。

The preliminary biological activity tests show that the title compounds have some fungicidal activities using Gibberella zeae, Rhizoctonia solani, Fusarium oxysporium and Sclerotinia sclerotiorum as the target fungus, but all of them have poor fungicidal activity to Fusarium oxysporium.

生物活性测试结果表明：所合成的目标化合物对受试菌种小麦赤霉病菌，水稻纹枯病菌、棉枯萎病菌和油菜菌核病菌均表现出一定的抑制活性，但对棉枯萎病菌的抑制活性均较差。

The experiments of the biological activity for target molecula were accomplished. The experiment results of inhibiting activity against COX-2 indicated that the compound TM-II-5f had the highest inhibition rate, up to 95.59%, and yet the compound TM-II-5g exhibits weakly inhibiting activity.

对目标产物TM-II-5a~5g进行了生物活性研究，人环氧酶-2(COX-2)活性抑制实验结果表明：目标产物TM-II-5f对人环氧酶-2(COX-2)有很强的抑制活性，抑制率高达95.59%，目标产物TM-II-5g具有较弱的抑制率(0.61%)。

Thus, introduction of statine has become an efficient strategy for the the design of aspartic protease inhibitors.The unique properties of the ferrocenyl group has made ferrocene and its derivatives very popular molecules for biological applications.Among them there are compounds with antiproliferative effect,antibiotics,pesticidal activity,ect.

二茂铁自被合成以来因其具有许多独特的性质而受到广发的应用，许多二茂铁化合物具有抗菌、抗肿瘤、杀虫等活性，用它取代具有生物活性分子中某些芳香环或杂环可以提高整个分子的活性。

Study the bioactivity of the n-HA/PA66 composite and the effects it would be to body's metabolism of calcium and phosphorus ion in vivo.(3) Study the osteo-conductivity and the ability to repair bone defect of the porous n-HA/PA66 composite and the feasibility use it as the scaffold of bone tissue engineering. Objects and Methods as follows: 1.To evaluate the biocompatability of nano-hydroxyapatite crystals and polyamide composite (n-HA/PA66) with the L929 cells.To proceed the morphological observation and take pictures of L929 cells after 1d,2d,4d,and 7d of co-cultured with extract of n-HA/PA66 ,and direct contact with n-HA/PA66.To determine light absorbtion value of every hole under 500 nm with enzyme linked immunity instrument after 1 d,2 d,4 d,and 7 d of contact of n-HA/PA66 extract with L929 cells,and direct contact with n-HA/PA66.In the meanwhile calculate the relative multiplication rate of cells,and evaluate them by six degree tests for cytotoxicity. To investigate the acute and chronic toxic reaction on the whole body induced by the new nano-hydroapatite crystals and polyamide composite(n-HA/PA66)after implanting in vivo and its effects on partial constitution of animal organs after implanting in vivo,and evaluate the potential and degree of subcuticular stimulation reaction.

本实验主要由以下三部分组成：一、n-HA/PA66 复合材料在动物体内、体外的生物相容性及生物安全性评价二、n-HA/PA66 复合材料植入动物体内的生物活性及近期对机体钙、磷代谢影响的实验研究三、网孔 n-HA/PA66 复合材料作为支架修复兔桡骨节段缺损的动物实验研究主要研究目标及方法如下：参照 GB/T16886.5-1997-ISO 10993-5：1992《医疗器械生物学评价细胞毒性试验体外法》之评价标准和要求，采用规定的 L929 细胞(小鼠结缔组织成纤维细胞)，分别经直接接触和材料浸提液与细胞共培养等方式对 n-HA/PA66 复合材料进行细胞毒性测试，采用细胞形态观察法观察两种细胞各组在 24h、48h、72h、5 天后各时相点的细胞形态学变化，并在显微镜下照相，从而对细胞与材料的生物相容性进行定性评价；同时采用细胞生长抑制法，以酶标仪定量测定评价各组 1，2，4，7 天 L929 细胞的相对增殖率，以定量测定并判别材料对细胞的毒性程度。

For researching the fungistasis activity of broom cypress seed, this experiment used the tracing method of bioactivity to investigate fungistasis active component. Its ingredient were separated by column chromatography.

为探索藜科地肤属植物地肤种子的杀菌抑菌活性，本试验采用生物活性跟踪法对该植物的杀菌抑菌活性成分进行了初步的研究，并采用柱层析法对其成分进行分离。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。