生物技术的

The detection instrument is an important component of biochip technology.

生物芯片探测技术是生物芯片技术中的重要组成部分。

This showed that capacity of water-holding in biological soil crusts were obvious improve,and effected precipitation permeate or water second distribute process.The study results of"fertile islands"formation mechanism in biological crusts showed that biological crusts layer cover could increased nutrients content for below sand soil through precipitation permeate washing,and it promoted plants assimilate more nutriment.The matter import ways of biological soil crusts fertility island had many ways,including the effection of living macrobiotics metabolism in crusts levels,wind-sand flow of near surface,dust deposition and plants decomposition course,etc.Source of particle matter in biological soil crusts was wind-sand flow of near surface,and not dust deposition.Biological crusts layer cover had preserved effection for nature water content in 0-5cm soil layer,compared with the sand of no biological crusts layer,effecting precipitation permeate,and could not obvious restrained from the water evaporate process indoor experiment.

生物结皮层肥岛形成机制的研究结果表明：生物结皮层覆盖能够通过降水淋溶作用而增加下层土壤养分的含量，进而促进植物对养分的吸收；生物结皮层养分输入有结皮生物代谢、降尘、风沙流和植物分解矿化作用等多(来源：A73e3B3eC论文网www.abclunwen.com)种途径，但生物结皮层的颗粒物质来源主要是近地表风沙流，而不是大气降尘；生物结皮层覆盖对0-5cm土层自然含水量有一定的保护作用，并影响降水向深层渗透，不能有效的阻止表层水分的蒸发进程；研究表明采取人工促进技术能够在流动沙丘上形成生物结皮层，实现流动沙地的快速治理。

The biological reduction of phosphate to phosphine can be used to develop a new biotechnology for anaerobic phosphate removal from wastewater.

以磷酸盐生物还原反应为基础的厌氧生物除磷技术，是一项尚待开发的新型生物除磷技术，具有很高的应用价值。

To understand how to use differential centrifugation to separate organelle and biological molecular;microspectrophotometry;immunofluorescence technifue and immune electron microscopy;in situ hybridization; aser scanning confocal microscopy;the method to show the nucleic acid、protein、enzyme、glucide and lipid; negative staining; freeze etching and quick freeze deepetching; flow cytometry.

了解用超速离心技术分离细胞器与生物大分子；显微分光光度测定技术；免疫荧光技术与免疫电镜技术；原位杂交技术；激光共焦点扫描显微镜技术；细胞内核酸、蛋白质、酶、糖类与脂质等的显示方法；负染色技术冷冻断裂和冷冻蚀刻电镜技术；流式细胞仪。

The courses in this academic program are political theory, foreign languages, applied computational technology, experimental biology, microbiology, molecular biology, genetic engineering, bioseparation engineering, bioreaction engineering, chemical thermodynamics, mass transfer, chemical process simulation, pharmacology, preparation of finished traditional Chinese medicines, pharmaceutical chemistry, GMP in pharmaceutical industry, liquid-to-liquid extraction, pharmaceutical properties measurement and quality control, pharmacy administration, etc.

其工程硕士学位授权单位培养从事生物制药、合成制药、中药开发、药剂、药物性能检测与分析的高级工程技术人才。研修的主要课程有：政治理论课、外语课、数值分析、计算机应用技术、现代生物学与技术实验、现代微生物学、分子生物学、基因工程、生物分离工程、生物反应工程、化工热力学、化工传递过程原理、化工过程模拟、药理学新进展、中成药的制备、药物化学的进展、制药工业的GMP、液液萃取基础、药品性能检测与质量控制、药业管理学等。

The biomarkers such as the n-Alkanes, the isoprenoids, the terpane, and cholestane were detected through GC-MS analysis. Based on the study of the biomarkers, the biological evolution during Permian and Triassic can be divided as three stages, namely, the mixing source stage of low biota such as thallose and advanced plant in late Permian (below bed 63), the stage of low biota such as thallose in the boundary transitional layer (bed 63-69) and the mixing source stage of advanced plant and low biota such as thallose in early Triassic (above bed 69). What's more, the second stage near the boundary transitional layer can be subdivided into 4 stages. The stages of biota evolution is close related with sedimentary environment changing and the boundary transitional layer.

利用GC—MS分析技术，在陆相地层中检测出正构烷烃、类异戊二烯烷烃、萜烷和甾烷类生物标志化合物并根据生物标志化合物和特征值研究，将二叠系—三叠系生物演化划分为三个大的阶段，即晚二叠世的菌藻类低等生物与高等植物混源阶段（63层以下），界线异常层的菌藻类低等生物阶段（63-69层）和早三叠世高等植物与菌藻类低等生物混源阶段（69层以上），界线附近异常层的第二阶段又进一步细分为4个次一级阶段，生物演化阶段与沉积环境变化及界线异常层具有非常密切关系。

Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

成果包括：（1）在生物组织弹性成像方面，研究了多种图像校正方法和应变估计方法，进行了弹性重构和仿体、离体及在体超声弹性成像实验研究；（2）在生物微系统和微血管血流灌注成像方面，制备了三种不同包膜超声造影微泡，研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制，并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究；（3）在阵列式高强聚焦超声治疗与监控成像技术方面，设计制作了新的HIFU换能器，解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题，并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展，具有重要应用前景；（4）在语音听觉系统特别是嗓音康复方面，研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理，建立基于神经、肌肉和空气动力系统的综合补偿调节模型，提出了相应的评价系统。

Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

中文摘要：成果包括：（1）在生物组织弹性成像方面，研究了多种图像校正方法和应变估计方法，进行了弹性重构和仿体、离体及在体超声弹性成像实验研究；（2）在生物微系统和微血管血流灌注成像方面，制备了三种不同包膜超声造影微泡，研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制，并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究；（3）在阵列式高强聚焦超声治疗与监控成像技术方面，设计制作了新的HIFU换能器，解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题，并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展，具有重要应用前景；（4）在语音听觉系统特别是嗓音康复方面，研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理，建立基于神经、肌肉和空气动力系统的综合补偿调节模型，提出了相应的评价系统。

The cardinal research work is the following: First, analyzed the reason of innovation of to "Biochemistry" curriculum by modern educational technology, the idea and principle of innovation; Second, exploit "Biochemistry" network curriculum fore-six chapter radical content by instruction of educational and psychological theory , subject to Modern Far-distance Education Resource Construction Technical Specification put forth by Far-distance Education Resource Council of Education Department, and by using many kinds of application software; Third, made up module of "Biochemistry" network curriculum, categorize this discipline into preliminary knowledge structure units, made a lot of animated and graphical multimedia stoff and try to reveal new ideas and method, etc, of network curriculum; Finally,"Biochemistry" network curriculum has been used in practical teaching , and it has brought about a good effect and won students high praise

其主要研究的工作为：一、分析了为什么要用现代教育技术革新&生物化学&课程以及革新的观念和原则；二、在具体实践中，以教育心理学理论为指导，以教育部远程教育资源委员会提出的《现代远程教育资源建设技术规范》为依据，结合多种应用软件系统地开发了&生物化学&网络课程前六章的基础内容；三、构建了&生物化学&网络课程的模块结构，并对刻学科的基础知识部份内容作了初步的知识单元结构的化分，加工制作了相当数量的动画类素材及图形类素材，并力求通过&生物化学&网络课程开发的实践揭示网络课程开发中新的理念和方法等；四、将已开发的部份课程内容用于实际教学，效果较好，学生评价较高

The biological hydrogen is very important to solute the energy crisis and the environmental pollution. Our country works out the organic waste water zymotechnics biological hydrogen technology by the tired of oxygen active sludge and the organic waste water as produces raw material. It is proved by the experiment in HIT. This research was discovered first in our country and foreign and realized the experimental scale non-fossilization mold mushroom spawn for a long time to continue producing the biological hydrogen technology. It also realized the experimental scale continue to produce the hydrogen for a long time. It was a domain significant breakthrough in biological hydrogen.

生物制氢对于解决能源危机和环境污染都具有十分重要的意义，我国以厌氧活性污泥和有机质废水为生产原料的有机废水发酵法生物制氢技术在哈工大通过实验研究验证，该项研究在国内外首创并实现了中试规模连续非固定化菌种长期持续生物制氢技术，并实现了中试规模连续流长期持续产氢，是生物制氢领域的一项重大突破。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。