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To study the applicable prospect of suicide gene on tumor therapy in clinic,we cloned the gene of D-amino acid oxidase and the gene of yeast cytosine deaminase.We hope to establish the transgenic mices of DAAO gene and YCD gene,and the two transgenic strain mices are valuable animal system for studying the biological characteristic of DAAO gene and YCD gene ,for studing the killing activity of DAAO/D-Ala and YCD/5-FC gene therapy systems on tumor.The D-amino acid oxidase gene derived from R.gracilis and it could oxidize D-amino acids. Hydrogen peroxide(H2O2) is a reactive oxygen species generated in the deamination of D-Ala catalyzed by DAAO.

为了探讨自杀基因在临床肿瘤治疗中的应用前景,建立自杀基因肿瘤治疗评价的动物模型,我们克隆了D-氨基酸氧化酶(D-amino acid oxidase,DAAO)基因和酵母菌胞嘧啶脱氨酶(yeast cytosine deaminase,YCD)基因,希望建立DAAO基因及YCD基因转基因小鼠,为研究DAAO及YCD基因的生物学特性、开发和评价DAAO/D-Ala及YCD/5-FC自杀基因系统进行肿瘤治疗建立良好的实验动物模型。

Aging is a biological phenomenon that causes debilitation and death.

老化是一种生物学现象,它引起虚弱和死亡。

The applied of the chitosan was very extensive, it was in biology , medical science realm and food, cosmetics, environmental protection, spin and weave, print to dye, deckle industry all contain bigger application value.

壳聚糖的应用面广,它在生物学、医学领域以及食品、化妆品、环保、纺织、印染、造纸等工业上均有较大的应用价值。

Oleic acid 18:1(△9)dehydrogenate to linoleic acid 18:2(△9,12)at the action of FAD2. With the developing of molecular biotechnology,antisense FAD2 gene is widely introduced into oil plants by genetic manipulation of fatty acid metabolism.

近年来随着分子生物学技术的发展,反义FAD2基因在油料作物脂肪酸调控基因工程中得到广泛应用,获得了油酸含量很高的转基因玉米、大豆、花生、油菜等。

The research results can provide some bask information on the morphology, biology, manual domestication, propagation and protection of demoiselle cranes.

通过本文的研究,为蓑羽鹤的形态学、生物学、人工驯养、繁殖与保护提供一些基础资料。

In recent years, with the development of modern science and technology, people have put forward a great many new neutral difference equations in natural science and social science as biology, economics, demology, physics and control theory, etc.

近年来,随着科学技术的发展,在自然科学与社会科学的许多学科中,如生物学、经济学、人口学、物理学以及控制论等,人们不断提出大量新的中立型差分方程。

Old difficulties against the existence of God or its demonstrability, against the dogma of Creation, miracles, the human soul, and supernatural religion have been dressed in a new garb and urged by a modern school of scientists principally from the discoveries in geology, paleontology, biology, astronomy, comparative anatomy, and physiology.

旧的困难,针对存在的上帝或其demonstrability ,反对教条的创作,屡创奇迹,人的灵魂,是与神灵,宗教一直穿着一个新的外衣,并敦促所现代学校的科学家们主要是从发现,在地质学,古生物学生物学,天文学,比较解剖学,生理学。

The denaturation of the physical chemical and/or biological properties of collagen will lead to the risk of deformation and fracture in bone.

骨中胶原的物理化学和生物学性质的变化均会导致骨的变形和断裂的危险性的增加。

PCR is one of the common techniques in molecular biology, which can amplify nucleic acids through the cycle of denaturation, annealing and extension.

PCR是最常用的分子生物学技术之一,通过变性、退火和延伸的循环来完成核酸分子的大量扩增。

On the basis of analyzing the reservoir status of ZHAN 3 block in Shengli Oilfield, different nutrients were used to activate the indigenous microorganisms by utilizing the denature gradient gel electrophoresis under the condition of stratum.

在对胜利油田沾3区块油藏状况分析的基础上,模拟地层高温高压的条件利用分子生物学技术研究了不同激活剂对内源微生物的激活效果。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口,替代木托盘,免薰蒸,符合欧盟、北美各国对出口货物包装材料的法令要求;喷涂钢托盘适用于重载上货架之用,托盘表面根据需要制作成平板状、波纹状及间隔形式,满足不同的使用要求。

A single payment file can be uploaded from an ERP system to effect all pan-China RMB payments and overseas payments in all currencies.

付款指令文件可从您的 ERP 系统上传到我们的电子银行系统来只是国内及对海外各种币种付款。