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生物合成

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Since C6 and higher alcohols are not obtainable by a direct biochemical route, it is proposed to synthesize these using known chemical reactions, wherein the raw material for synthesis is biogas and lower C2-C5 alcohols obtained by the inventive method wherein the amino acids leucine, isoleucine, and valine, or a mixture thereof, optionally obtained from yeast autolysate, is used as a biocatalyst at the stage of fermentation.

因为C6和更高级醇类不能通过直接生物化学途径制得,所以提出用已知的化学反应合成这些化合物,其中合成的原料为本发明方法制得的生物气和C2-C5醇类,其中任选从酵母自溶作用得到的亮氨酸、异亮氨酸和缬氨酸或其混合物的氨基酸在发酵阶段用作生物催化剂。

In fact, the application of chiral ILs in asymmetric catalytic transformations is still at a preliminary stage.Benzoin is an important intermediate in organosynthesis. And more than, chiral benzoin is important structure unit of many bioactive compounds and building blocks of many enantioselective synthesis.

苯偶姻是一种重要的有机合成中间体,而且光学活性苯偶姻是许多生物活性化合物的重要结构单元,是可用于立体选择性合成生物活性有机分子的重要合成砌块。

Preliminary antitumor activity in vitro of the new compounds indicated that the compounds have obvious inhibitory effect on human leukaemia cell (HL-60) and human galactophore cancer cell (MDA-MB-468) in the concentration of 10-4 mol/L. This result is a basis for further study on the synthesis and biological activity of this kind of compounds.

对所合成的10个新化合物进行了抗肿瘤体外生物活性试验,初步生物活性实验结果表明,该类化合物在浓度为10-4 mol/L时对人白血病细胞株(HL-60)和人乳腺癌细胞株(MDA-MB-468)有明显的抑制作用,在浓度为10-5 mol/L时没有明显的抑制作用,这一研究结果为进一步研究此类化合物的合成、生物活性的研究奠定了基础。

The present dissertation reviews the total synthesis of biotin, particularly on Hoffmann-La Roche\'s Lactone-Thiolactone approach. The Lactone-Thiolactone approach is presently the most competitive commercial route, which gives an excellent illustration of the gradual construction of the functionalized skeleton with the simultaneous solution of the stereochemical issues in a minimal number of steps.In 1970, Gerecke etc. of Roche Corp.

论文对生物素全合成的文献进行了综述,重点讨论了目前工业上最有竞争力的内酯—硫代内酯路线,展示了生物素是如何以最少的步骤去逐步构建目标产物的官能团骨架并同时解决立体化学问题的。1970年,Roche公司的Gerecke等报道了一条通过手性内酯,以较高收率并保持构型得到手性硫代内酯,从而直接合成d-生物素的方法后,该中间体内酯(3aS,6aR)-1,3-二苄基。

In this article,the tripeptide RGD is synthesized by the method of liquid synthesis .

采用液相合成法合成了RGD 三肽并对其进行了生物活性检测,证实用液相合成的 RGD 短肽具有促进材料与内皮细胞粘附的生物活性。

The progress in waste oil and grease collection and disposal, especially the conversion technol- ogy of grease trap waste, the development of oil-rich plantation, advancement in bio-diesel synthesis technology, results of engine and road test are presented in this article. As a result, It forecasts that, two conversion technological process including bio-diesel made by waste grease especially from grease trap waste and wild oil-rich tree nuts to make bio-diesel will be the two main technologies, and which w...

分析了我国生物柴油产业在废弃油脂收集处理、植物原料开发、生物柴油合成技术、生物柴油车辆实验等方面的技术进步;提出利用野生树木种子和隔油池垃圾为主的废弃油脂生产生物柴油两条工艺路线是中国生物柴油发展的方向,这两条工艺路线将主导未来世界生物柴油产业,从而极大促进世界生物柴油产业的发展,生物柴油产量将会大幅度增加。

As a result, It forecasts that, two conversion technological process including bio-diesel made by waste grease especially from grease trap waste and wild oil-rich tree nuts to make bio-diesel will be the two main technologies, and which w.

分析了我国生物柴油产业在废弃油脂收集处理、植物原料开发、生物柴油合成技术、生物柴油车辆实验等方面的技术进步;提出利用野生树木种子和隔油池垃圾为主的废弃油脂生产生物柴油两条工艺路线是中国生物柴油发展的方向,这两条工艺路线将主导未来世界生物柴油产业,从而极大促进世界生物柴油产业的发展,生物柴油产量将会大幅度增加。

Then, the behavior properties of synthetic musks as POPs were analyzed on the basis of their biological accumulation, environmental degradation and biological transformation. Some visible adverse ecological effects including environmental hormone toxicity, genetic toxic effects, and physiological ecotoxicity of synthetic musks, and their influences on enzymatic activity, and their toxic effects on microorganisms were also summarized.

在此基础上,从人工合成麝香的生物蓄积行为、环境降解行为和生物转化行为等3个方面,对人工合成麝香所具有的持久性有机污染物的行为特征进行了分析;概述了人工合成麝香的环境激素毒性、遗传毒性效应、生理生态毒性、对酶活性的影响以及对微生物毒性效应的研究进展,展示了人工合成麝香所可能产生的不良生态效应。

Then, the behavior of synthetic musks as POPs is analyzed on the basis of their biological accumulation, environmental degradation and biological transformation. Some visible adverse ecological effects including environmental hormone toxicity, toxic genetic effects, and physiological ecotoxicity, plus the influence of synthetic musks on enzymatic activity, and their toxic effects on microorganisms are also summarized.

在此基础上,从人工合成麝香的生物蓄积行为、环境降解行为和生物转化行为等3个方面,对人工合成麝香所具有的持久性有机污染物的行为特征进行了分析;概述了人工合成麝香的环境激素毒性、遗传毒性效应、生理生态毒性、对酶活性的影响以及对微生物毒性效应的研究进展,展示了人工合成麝香所可能产生的不良生态效应。

The inhibited biological synthesis of NO and increased level of free radical can aggravate liver injury.

抑制NO的生物合成,自由基水平增高,从而加重了肝损伤。

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