生物化学的

The principle fields of the Institute's activity are related to molecular genetics, cytogenetics, immunogenetics, embryology, biochemistry, the physiology of animal stress and ethology, embryo biotechnology and biotechnics, introductions of the results of basic investigations into animal improvement programmes, determination of animal genotypes and their adaptation to environmental conditions and production demands.

该所的主要活动领域是关于分子遗传学、细胞遗传学、免疫遗传学、胚胎学、生物化学、动物胁迫和动物行为方面的生理学、胚胎生物技术和应用生物学、改善动物的项目基础研究结果的介绍、动物基因型的决定及其对环境条件的适应与产品要求等方面的内容。

On the basis of this system andpreviously morphological, physiological and biochemical studies on cucumber in vitrogynogenesis. Materials from both typical gynogenesis using M99 as induction medium andnon gynogenesis using W5 as induction medium were collected. The activities anddistribution of peroxidase and its isoenzymes, content of soluble protein and distribution of allprotein during early stage of cucumber in vitro gynogenesis and non gynogenesis wereinvestigated by biochemistry and histochemistry technology.

本试验在前期有关离体黄瓜雌核发育形态学和生理生化研究的基础上，以诱导离体雌核发育的 M99 培养基上和非雌核发育的 W5 培养基上培养的黄瓜未受精子房为试材，采用生物化学技术和组织化学技术，深入研究了离体雌核发育早期外植体内的标志酶——过氧化物酶及其同工酶的活性及分布的变化、可溶性蛋白质的含量和总蛋白质分布的变化及核酸和多糖分布的变化，为揭示离体雌核发育早期的细胞分化机制提供科学依据。

Titin is recently known as the largest protein which exists in the stiated muscle sarcomere and is dynamic both in biomechanics properties and biochemical functions. Four possible disease-associated mutations located in three exons(3,14,49) of titin gene have been identified in Japanese DCM patients in 2002. But we did nothing about the creative titin and DCM.

目的：肌联蛋白是由单基因编码的最大蛋白，普遍存在于心肌和骨骼肌，被称为第三肌丝，具有复杂的生物力学性质和生物化学功能。2002年日本研究人员报道了肌联蛋白基因第3、14、49外显子的4个基因突变可能与扩张性心肌病发病相关，而我国没有相关的研究报道。

This paper reviews the recent progress on the Chinese syntheic research of marine natural products according to type classifications: marine cyclopeptides, cembranes, cembrenss, cembranolides, quinolone derivativcs, triacetonamine and subergorgic acid analogues.

由于海洋中的生物资源非常丰富，海洋中的生态环境与陆地显著不同，因此海洋天然产物具有独特的化学·结构和多种多样的生理活性。对这些物质的合成进行深入地研究，必将丰富天然产物化学的内容，促进有机化学基础

The courses in this academic program are political theory, foreign languages, applied computational technology, experimental biology, microbiology, molecular biology, genetic engineering, bioseparation engineering, bioreaction engineering, chemical thermodynamics, mass transfer, chemical process simulation, pharmacology, preparation of finished traditional Chinese medicines, pharmaceutical chemistry, GMP in pharmaceutical industry, liquid-to-liquid extraction, pharmaceutical properties measurement and quality control, pharmacy administration, etc.

研修的主要课程有：政治理论课、外语课、数值分析、计算机应用技术、现代生物学与技术实验、现代微生物学、分子生物学、基因工程、生物分离工程、生物反应工程、化工热力学、化工传递过程原理、化工过程模拟、药理学新进展、中成药的制备、药物化学的进展、制药工业的 GMP、液液萃取基础、药品性能检测与质量控制、药业管理学等。

In order to overcome the problem of multidrug resistance in human epidemic carcinomata anti-adriamycin cells (KB-A-1), the antisense and antigene oligonucleotides were used to investigate their effectiveness on inhibiting the mdr1 gene expression. The effectiveness of antisense or antigene oligonucleotide on inhibiting the multidrug resistance was detected by MTT colometric assay and ELISA.

中文题名反义与反基因寡核苷酸及其萘二酰亚胺偶联物对靶基因表达的抑制作用研究副题名外文题名 The inhibition of the targeted gene expression by the antisense or antigene oligonucleotides and their naphthylimide-conjugated derivatives 论文作者李军生导师张元兴魏东芝教授学科专业生物化工研究领域\研究方向生物化学与分子生物学学位级别博士学位授予单位华东理工大学学位授予日期2001 论文页码总数106页关键词基因表达基因治疗反义寡核苷酸反基因寡核苷酸核酸馆藏号BSLW /2001 /Q78 /264 针对人表皮癌抗阿霉素细胞株（KB-A-1）的多药抗药性问题，本文从反义核酸和反基因核酸角度，通过MTT法检测细胞生长情况，ELISA法检测基因表达产物P-gp表达水平的变化，对寡核苷酸抑制肿瘤细胞MDR1基因表达的机制进行了探讨。

Recent study proved that the thickness, microstructure, chemistry composition of oxide film can affected the biological corrosion-resistance ability, hydrophile property and bioactive macro molecule absorption, then affected the biocompatibility and the match process in the body.

目前的研究认为钛表面氧化膜的厚度、微观结构、化学成分及TiO_2的结构类型等，与材料的耐腐蚀性、表面亲水性和生物大分子的选择性吸附有着直接的关系，进而影响到钛的生物相容性以及在体内的愈合过程。

In order to transform Spartina alterniflora, an invasive species widely distributing on Chinese coast, into clean energy, the feasibility of anaerobic digestion of S. alterniflora was analyzed by its biological structure using the SEM and its chemical composition using the Elementor and ICP-AES, at the same time the anaerobic batch digestion experiments were carried out at 35℃.

针对互花米草这一广泛分布在中国海滩上的外来植物的资源化利用问题，通过对其生物结构的SEM观察，以及化学组成的测试分析，探讨了对其进行厌氧生物转化利用的可行性；同时，在35℃条件下采用批量发酵方式进行了厌氧发酵试验。

The research on artificial nucleases has been one of the most active frontiers of biochemistry and molecular biology. The investigation on DNA and transition metal complexes as the potential artificial nucleases is the significant branch of bioinorganic chemistry, and is of important theory and application values.

人工核酸切割试剂的研究一直是生物化学和分子生物学最为活跃的研究领域之一，过渡金属配合物作为潜在的人工核酸酶与DNA的作用是生物无机化学研究领域的重要分支，具有很重要的理论价值和应用价值。

His current research interests include: biochemical studies of metallothionein-like metal binding proteins and phytochelatins in plants; immobilised algal biotechnology; and conservation strategies for mangroves and their application in sewage treatment.

目前他致力於研究以下项目：类金属硫蛋白的金属结合蛋白的生物化学以及植物的鳌剂研究；固定化微藻的生物工艺学研究；研究保护红树林策略以及利用红树林进行废水处理。

Fancy gold-plated dangling earrings with facetted White Opal crystals.

花式镀金悬垂耳环与facetted白欧泊水晶。

This essay chooses the study aim from biology teachers in middle school in Shi Jiazhuang which tells us that most of the middle school biology teachers in Shi Jiazhuang have the"burnout", lower successfulness, individualize.

本文选取石家庄市初中生物教师作为研究对象，运用问卷调查的方法对石家庄市初中生物教师职业倦怠的现状进行调查，调查结果发现，石家庄市初中生物教师这一群体普遍存在职业倦怠，情感枯竭程度偏高，成就感偏低，去个性化程度最为严重。