甘草酸

The yield of monoammonium glycyrrhizinate was 1.30% and content was 95% by the lixiviation, ammoniation, acidation, decoloration and recrystal.

经过浸提、氨化、酸化、脱色、重结晶过程可得到含量为95%的甘草酸铵，甘草酸铵的最终提取率为1.30%。

The Gaoshawo provenience showed a better growth status in plain region by comparing with the Hangjinqi provenience of the seedling physiological characterization and the medicinal composition content of the annual root.

对一年生直播甘草的分析表明，主根长度与甘草苷含量达到显著正相关水平，根重与甘草酸和甘草苷含量均呈一定程度的正相关；甘草苷含量与甘草酸含量呈极显著正相关关系，说明甘草酸和甘草苷的积累速度具有协同性。

The optimum process was as follows : solvent is 0.3% ammonia solution , ratio of solvent to solid ratio is 10:1 , vacuum-cavitated time is 15 minutes , GA extraction yeild is 2.0%, the crude extract is 30.3%, and in which the content of GA is 6.6%.

采用负压空化方法对超临界萃取后固形物中甘草酸的提取工艺进行了研究，并研究了甘草酸纯化的工艺，通过影响因素试验和正交试验得出最佳工艺条件为：0.3%的稀氨水为溶剂，液固比为10：1，负压空化提取15min，甘草酸提取率为2.0%，含量6.6%。

AIM:To study the therapeutic effect of Diammonium Glycyrrhizinate lipid ligand on alcoholic fatty liver.

目的 ：观察新一代甘草酸制剂甘草酸二铵脂质配位体对酒精性脂肪肝的治疗作用。

The temperature affects partition of dipotassium glycyrrhizinat but the effect is minor. On the same time pH has major impact on the partition of dipotassium glycyrrhizinat. The coefficient is eight times higher when pH reaches 2. The improved Diamond-Hsu model can be used to correlate the partition coefficient of dipotassium glycyrrhizinat in the system of water/ethanol/isobutanol. The result of Infrared and TG analysis indicate the extraction product has the same characteristic features with dipotassium glycyrrhizinat.

结果表明：体系的初始点越靠近临界点，甘草酸二钾的分配系数越大；温度对甘草酸二钾的分配有～定的影响，但分配系数随温度变化不大；pH值对甘草酸二钾的分配有较大的影响，在pH=2附近，分配系数高出其他位置达8倍；改进的Diamond-Hsu模型可以用于关联甘草酸二钾在水+乙醇+异丁醇体系中的分配系数；红外和TG分析结果表明萃取产物与甘草酸二钾样品的性质特征相同。

The product includes the licorice frost, licorice paste, licorice acid, Acetyl Glycyrrhetic Acid, Crude Disodium Glycyrrhizininate, Dipotassium Glycyrrhizininate, Monopotassium Glycyrrhizininate, Diammonium GlycyrrhizininateDiammonium Glycyrrhizininate, Monoammonium Glycyrrhizininate etc.

产品有甘草霜、甘草膏、甘草酸、乙酰甘草次酸、甘草酸单铵盐、甘草酸单钾盐、甘草酸二钾盐、甘草酸三钾盐、甘草酸二钠盐、高纯甘草酸等品种。

Monoaminonium Glycyrrhizinate、Diammonium Glycyrrhizinate、Monopotassium Glycyrrhizinate、Glycyrrhinic Acid、Glycyrrhetinic Acid、Dipotassium Glycyrrhizinate、Licorice Extract Block、Licorice Extract Powder、Matrine、Oxymatrine、Astragalus、Black Cohosh、Epimedium、Ginkgo Biloba、Maitake Mushroom、Red Clover、Glabridin.

甘草酸单铵、甘草酸二铵、甘草酸单钾、甘草酸二钾、甘草黄酮、甘草酸、甘草次酸、甘草浸膏、苦参碱、氧化苦参碱、植物提取物（黄芪、黑升麻、淫羊藿、银杏、灰树花、红东轴等等）、光甘草定。

The results showed that the content of glycyrrhizic acid in wild glycyrrhiza is higher than that in cultivated glycyrrhiza.

结果表明，野生甘草中甘草酸的含量要高于人工栽培，三年生甘草中甘草酸的含量最高，根中甘草酸的含量要高于茎和叶。

The present invention discloses one kind of compound preparation comprising monopotassium glycyrrhizunate 20-75 weight portions, glycine 1-800 weight portions, L-cysteine hydrochloride 10-28 weight portions, and one or two of sodium chloride 10-30 weight portions, anhydrous sodium sulfite 10-28 weight portions and disodium edetate 1-9 weight portions.

本发明公开了一种含甘草酸单钾盐的复合制剂，由下述重量配比的组分制成：甘草酸单钾盐20-75份，甘氨酸1-800份，L-盐酸半胱氨酸10-28份，和氯化钠10-30份，无水亚硫酸钠10-28份，依地酸二钠1-9份中的一种或两种以上的混合。

The glycyrrhizic acid antigen is prepared through the process including following steps: dissolving glycyrrhizic acid in N, N-dimethyl formamide, dioxane or dimethyl sulfoxide, heliophobically adding N-hydroxy succinimide, reacting with dicyclohexylcarbodiimide at 0-10 deg.c for 2-5 hr; and reacting with carrier protein at normal temperature for 4-6 hr to obtain glycyrrhizic acid antigen.

本发明所提供的甘草酸抗体，是用甘草酸抗原免疫动物，然后从被免疫动物的血清中分离得到的；所述甘草酸抗原按如下过程制备：先将甘草酸溶解在N，N-二甲基甲酰胺、二氧六环或二甲基亚砜中，避光加入N-羟基琥珀酰亚胺，然后在0-10℃条件下与二环己基碳二亚胺反应2-5小时；接着与载体蛋白常温反应4-6小时，得到甘草酸抗原。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。