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甘氨酸

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I have found that the cross-talk between GABA_ARs and GlyRs is regionally regulated and shaped by receptor expression level.

作者发现,GABA_A和甘氨酸受体之间的对话与区域相关和受体表达水平相关。

The productions of glycin oxidation are complicated and the cost is high. The cyanogenesis is poisonous and unsafe.

国内外合成羟基乙酸的方法主要有甘氨酸氧化法、氰化法、醛类羧化法、甲醛和甲酸甲酯偶联法、草酸电解法、氯乙酸水解法等。

The resultant was hydrogenised to remove protective group of amino group, then the product was reacted with NaNO2 to give diazonium salt, which was conjugated with salicylic acid, hydroxybenzene, N-salicyloyl glycine acid to get azo derivatives of 4-ASA.

本文首先对4-ASA的氨基和羟基进行了选择性保护,通过氢化还原法选择性脱除氨基的保护基,然后将氢化产物制成重氮盐,通过与水杨酸、苯酚和水杨酰甘氨酸发生反应生成4-ASA的偶氮衍生物,最后在碱性条件下水解得到最终产物。

According to the experimental product, the X-ray powder diffraction bread peak curve derived from it is amorphous, with no diffraction peak of copper in glycine template.

根据实验所得的产物其X-射线粉末衍射曲线呈馒头峰是非晶态,没有出现模板甘氨酸铜的衍射峰。

In this report, the 59Tc labelling of Annexin V fragment modified with HYNIC (HYNIC-Anx13) using Tricine, EDDA or EDDA/Tricine as coligands was described. The effect of various factors on 99Tc labelling was investigated. Biodistribution studies in normal mice and gamma imaging of apoptosis in rats induced by cyclophosphamide were performed.

为探讨99Tc标记的HYNIC-Anx13用于细胞凋亡显像的可能性,分别以N-[三甲基]甘氨酸,乙二胺-N,N'-二乙酸和EDDA/Tricine为协同配体,对经6-肼基烟酰基修饰的膜联蛋白V片段(HYNIC-Anx13)的99Tc标记条件和主要影响因素进行了研究,并完成了HYNIC-Anx13的99Tc标记物在正常小鼠体内的生物分布和大鼠细胞凋亡模型的显像实验。

Methods: TOCA was labeled with (superscript 99m)Tc using HYNIC as bifunctional chelator, EDDA and trieine as coligand. The nude mice bearing human small cell lung cancer underwent static whole body planar imaging after the injection of (superscript 99m)Tc-HYNIC-TOCA or (superscript 99m)Tc-P829. ROIs were drawn and the radioactivity ratios of target to non-target were calculated in every planar imaging. The dynamic biodistribution study was operated in Kunming mice and the percent uptake ratios of two imaging agents in different tissue at different time were measured.

以HYNIC为双功能螯合剂(bifunctional chelator, BFC),乙二胺-N,N'-二乙酸和三甲基甘氨酸为协同配体进行TO-CA的(上标 99m)Tc标记;以(上标 99m)Tc-HYNIC-TOCA和(上标 99m)Tc-P829为显像剂,对荷人类小细胞肺癌裸鼠进行显像,通过感兴趣区技术进行半定量分析,计算并比较两种显像剂的靶/非靶比值;在昆明鼠体内进行动态生物学分布实验,测定并比较不同时点两种显像剂在各脏器的克组织百分摄取率。

OBJECTIVE: To explore the effect of glycine on serum levels of IL-1 and IL-6 in rats with necrotizing enterocolitis induced by endotoxin and hypoxia.

目的:探讨甘氨酸对内毒素和缺氧诱导的坏死性肠炎鼠血清炎性因子IL-1与IL-6的作用。

In presence of this catalyst,ethanolamine reacted with alkali water at 140-170 ℃ and H2 pressure of 0.8-1.2 MPa.The conversion was over 98% and selectivity for glycine was higher than 95%.

实验结果表明:在温度140170 ℃,H2压力0.81.2 MPa,一乙醇胺与碱水催化反应,其转化率可达98%以上,甘氨酸的选择性高于95%。

Sodium salt of ethylenediamine tetraacetic acid and glycine).

乙二胺四醋酸和甘氨酸的钠盐。

AIM: To study the effect of glycine on body weight and lipid metabolism in mice.

目的: 观察甘氨酸对正常饮食和高脂饮食小鼠体重及血脂代谢的影响。

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